3CGF
| IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding | Descriptor: | Mitogen-activated protein kinase 10, N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine | Authors: | Ceska, T.A, Platt, A, Fortunato, M, Dickson, K.M, Buckley, G. | Deposit date: | 2008-03-05 | Release date: | 2008-06-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding Bioorg.Med.Chem.Lett., 18, 2008
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3ARL
| Cl- binding hemoglobin component V form Propsilocerus akamusi under 500 mM NaCl at pH 5.5 | Descriptor: | CHLORIDE ION, Hemoglobin V, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kuwada, T, Hasegawa, T, Takagi, T, Shishikura, F. | Deposit date: | 2010-12-02 | Release date: | 2011-04-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Involvement of the distal Arg residue in Cl- binding of midge larval haemoglobin Acta Crystallogr.,Sect.D, 67, 2011
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3AYC
| Crystal structure of galectin-3 CRD domian complexed with GM1 pentasaccharide | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, Galectin-3, ... | Authors: | Bian, C.F, Li, D.F, Wang, D.C. | Deposit date: | 2011-05-04 | Release date: | 2011-10-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for distinct binding properties of the human galectins to thomsen-friedenreich antigen Plos One, 6, 2011
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3AYF
| Crystal structure of nitric oxide reductase | Descriptor: | (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Matsumoto, Y, Tosha, T, Pisliakov, A.V, Hino, T, Sugimoti, H, Nagano, S, Sugita, Y, Shiro, Y. | Deposit date: | 2011-05-06 | Release date: | 2012-01-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus Nat.Struct.Mol.Biol., 19, 2012
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3AYG
| Crystal structure of nitric oxide reductase complex with HQNO | Descriptor: | (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, CALCIUM ION, ... | Authors: | Matsumoto, Y, Tosha, T, Pisliakov, A.V, Hino, T, Sugimoti, H, Nagano, S, Sugita, Y, Shiro, Y. | Deposit date: | 2011-05-06 | Release date: | 2012-01-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus. Nat.Struct.Mol.Biol., 19, 2012
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3AX6
| Crystal structure of N5-carboxyaminoimidazole ribonucleotide synthetase from Thermotoga maritima | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphoribosylaminoimidazole carboxylase, ATPase subunit | Authors: | Miyazawa, R, Kanagawa, M, Baba, S, Nakagawa, N, Ebihara, A, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2011-03-30 | Release date: | 2012-04-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of N5-carboxyaminoimidazole ribonucleotide synthetase, PurK, from thermophilic bacteria To be Published
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3AZO
| Crystal structure of puromycin hydrolase | Descriptor: | Aminopeptidase, SULFATE ION | Authors: | Matoba, Y, Sugiyama, M. | Deposit date: | 2011-05-27 | Release date: | 2011-07-27 | Last modified: | 2011-09-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural evidence that puromycin hydrolase is a new type of aminopeptidase with a prolyl oligopeptidase family fold Proteins, 79, 2011
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1QKP
| HIGH RESOLUTION X-RAY STRUCTURE OF AN EARLY INTERMEDIATE IN THE BACTERIORHODOPSIN PHOTOCYCLE | Descriptor: | BACTERIORHODOPSIN, RETINAL | Authors: | Edman, K, Nollert, P, Royant, A, Belrhali, H, Pebay-Peyroula, E, Hajdu, J, Neutze, R, Landau, E.M. | Deposit date: | 1999-07-30 | Release date: | 1999-10-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | High-resolution X-ray structure of an early intermediate in the bacteriorhodopsin photocycle. Nature, 401, 1999
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3AZP
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1QMD
| calcium bound closed form alpha-toxin from Clostridium perfringens | Descriptor: | CALCIUM ION, PHOSPHOLIPASE C, ZINC ION | Authors: | Naylor, C.E, Miller, J, Titball, R.W, Basak, A.K. | Deposit date: | 1999-09-27 | Release date: | 2000-02-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterisation of the Calcium-Binding C-Terminal Domain of Clostridium Perfringens Alpha-Toxin J.Mol.Biol., 294, 1999
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1QM6
| Closed form of Clostridium perfringens alpha-toxin strain NCTC8237 | Descriptor: | PHOSPHOLIPASE C, ZINC ION | Authors: | Naylor, C.E, Miller, J, Titball, R.W, Basak, A.K. | Deposit date: | 1999-09-21 | Release date: | 1999-09-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Characterisation of the Calcium-Binding C-Terminal Domain of Clostridium Perfringens Alpha-Toxin J.Mol.Biol., 294, 1999
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3B3P
| Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2-diamine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine, ... | Authors: | Igarashi, J, Li, H, Poulos, T.L. | Deposit date: | 2007-10-22 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors. J.Med.Chem., 52, 2009
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1QK1
| CRYSTAL STRUCTURE OF HUMAN UBIQUITOUS MITOCHONDRIAL CREATINE KINASE | Descriptor: | CREATINE KINASE, UBIQUITOUS MITOCHONDRIAL, PHOSPHATE ION | Authors: | Eder, M, Schlattner, U, Fritz-Wolf, K, Wallimann, T, Kabsch, W. | Deposit date: | 1999-07-08 | Release date: | 2000-04-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of Human Ubiquitous Mitochondrial Creatine Kinase Proteins: Struct.,Funct., Genet., 39, 2000
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3B4N
| Crystal Structure Analysis of Pectate Lyase PelI from Erwinia chrysanthemi | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Endo-pectate lyase, ... | Authors: | Creze, C, Castang, S, Derivery, E, Haser, R, Shevchik, V, Gouet, P. | Deposit date: | 2007-10-24 | Release date: | 2008-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Crystal Structure of Pectate Lyase PelI from Soft Rot Pathogen Erwinia chrysanthemi in Complex with Its Substrate. J.Biol.Chem., 283, 2008
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3BD9
| human 3-O-sulfotransferase isoform 5 with bound PAP | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Heparan sulfate glucosamine 3-O-sulfotransferase 5 | Authors: | Xu, D, Moon, A.F, Song, D, Liu, J, Pedersen, L.C. | Deposit date: | 2007-11-14 | Release date: | 2008-01-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Engineering sulfotransferases to modify heparan sulfate. Nat.Chem.Biol., 4, 2008
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1QMY
| FMDV LEADER PROTEASE (LBSHORT-C51A-C133S) | Descriptor: | 1,2-ETHANEDIOL, PROTEASE | Authors: | Guarne, A, Tormo, J, Glaser, W, Skern, T, Fita, I. | Deposit date: | 1999-10-08 | Release date: | 2000-10-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Biochemical Features Distinguish the Foot-and-Mouth Disease Virus Leader Proteinase from Other Papain-Like Enzymes J.Mol.Biol., 302, 2000
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3COK
| Crystal structure of PLK4 kinase | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, Serine/threonine-protein kinase PLK4 | Authors: | Atwell, S, Burley, S.K, Houle, A, Leon, B, Pelletier, L.A, Sauder, J.M, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-03-28 | Release date: | 2008-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of PLK4 kinase. To be Published
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3CSM
| STRUCTURE OF YEAST CHORISMATE MUTASE WITH BOUND TRP AND AN ENDOOXABICYCLIC INHIBITOR | Descriptor: | 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, CHORISMATE MUTASE, TRYPTOPHAN | Authors: | Straeter, N, Schnappauf, G, Braus, G, Lipscomb, W.N. | Deposit date: | 1997-07-10 | Release date: | 1998-01-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures. Structure, 5, 1997
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3A2P
| Structure of 6-aminohexanoate cyclic dimer hydrolase | Descriptor: | 6-aminohexanoate-cyclic-dimer hydrolase, GLYCEROL | Authors: | Shibata, N. | Deposit date: | 2009-05-26 | Release date: | 2009-11-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystallographic analysis of the 6-aminohexanoate cyclic dimer hydrolase: catalytic mechanism and evolution of an enzyme responsible for nylon-6 byproduct degradation J.Biol.Chem., 285, 2010
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3A5D
| Inter-subunit interaction and quaternary rearrangement defined by the central stalk of prokaryotic V1-ATPase | Descriptor: | V-type ATP synthase alpha chain, V-type ATP synthase beta chain, V-type ATP synthase subunit D, ... | Authors: | Numoto, N, Hasegawa, Y, Takeda, K, Miki, K. | Deposit date: | 2009-08-06 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.8 Å) | Cite: | Inter-subunit interaction and quaternary rearrangement defined by the central stalk of prokaryotic V1-ATPase Embo Rep., 10, 2009
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3A9Y
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3ADC
| Crystal structure of O-phosphoseryl-tRNA kinase complexed with selenocysteine tRNA and AMPPNP (crystal type 2) | Descriptor: | L-seryl-tRNA(Sec) kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Itoh, Y, Chiba, S, Sekine, S, Yokoyama, S. | Deposit date: | 2010-01-18 | Release date: | 2010-07-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine Mol.Cell, 39, 2010
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3A2B
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3AMV
| ALLOSTERIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG | Descriptor: | 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, GLYCEROL, PROTEIN (GLYCOGEN PHOSPHORYLASE), ... | Authors: | Oikonomakos, N.G, Tsitsanou, K.E, Zographos, S.E, Skamnaki, V.T. | Deposit date: | 1999-02-18 | Release date: | 1999-02-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate. Protein Sci., 8, 1999
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365D
| STRUCTURAL BASIS FOR G C RECOGNITION IN THE DNA MINOR GROOVE | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*GP*(CBR)P*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE | Authors: | Kielkopf, C.L, Baird, E.E, Dervan, P.B, Rees, D.C. | Deposit date: | 1997-12-17 | Release date: | 1998-02-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for G.C recognition in the DNA minor groove. Nat.Struct.Biol., 5, 1998
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