7NKH
| Mycobacterium smegmatis ATP synthase F1 state 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-18 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NJR
| Mycobacterium smegmatis ATP synthase state 3b | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NJL
| Mycobacterium smegmatis ATP synthase state 1b | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NJM
| Mycobacterium smegmatis ATP synthase state 1c | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6MOA
| C-terminal bromodomain of human BRD2 in complex with 4-(2-cyclopropyl-7-(6-methylquinolin-5-yl)-1H-benzo[d]imidazol-5-yl)-3,5-dimethylisoxazole inhibitor | Descriptor: | 4-(2-cyclopropyl-7-(6-methylquinolin-5-yl)-1H-benzo[d]imidazol-5-yl)-3,5-dimethylisoxazole, Bromodomain-containing protein 2, GLYCEROL | Authors: | Lansdon, E.B, Newby, Z.E.R. | Deposit date: | 2018-10-04 | Release date: | 2019-01-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.271 Å) | Cite: | Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor. Bioorg. Med. Chem., 27, 2019
|
|
5UVK
| Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation | Descriptor: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN | Authors: | Martin-Garcia, J.M, Conrad, C.E, Nelson, G, Stander, N, Zatsepin, N.A, Zook, J, Zhu, L, Geiger, J, Chun, E, Kissick, D, Hilgart, M.C, Ogata, C, Ishchenko, A, Nagaratnam, N, Roy-Chowdhury, S, Coe, J, Subramanian, G, Schaffer, A, James, D, Ketawala, G, Venugopalan, N, Xu, S, Corcoran, S, Ferguson, D, Weierstall, U, Spence, J.C.H, Cherezov, V, Fromme, P, Fischetti, R.F, Liu, W. | Deposit date: | 2017-02-20 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. Iucrj, 4, 2017
|
|
7NJN
| Mycobacterium smegmatis ATP synthase state 1d | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NJS
| Mycobacterium smegmatis ATP synthase state 3c | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
1D4E
| CRYSTAL STRUCTURE OF THE FLAVOCYTOCHROME C FUMARATE REDUCTASE OF SHEWANELLA PUTREFACIENS STRAIN MR-1 COMPLEXED WITH FUMARATE | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C FUMARATE REDUCTASE, FUMARIC ACID, ... | Authors: | Leys, D, Tsapin, A.S, Meyer, T.E, Cusanovich, M.A, Van Beeumen, J.J. | Deposit date: | 1999-10-03 | Release date: | 1999-12-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1. Nat.Struct.Biol., 6, 1999
|
|
1D4Z
| CRYSTAL STRUCTURE OF CHEY-95IV, A HYPERACTIVE CHEY MUTANT | Descriptor: | CHEMOTAXIS PROTEIN CHEY, SULFATE ION | Authors: | Schuster, M, Zhao, R, Bourret, R.B, Collins, E.J. | Deposit date: | 1999-10-06 | Release date: | 1999-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Correlated switch binding and signaling in bacterial chemotaxis. J.Biol.Chem., 275, 2000
|
|
6I37
| Crystal structure of nv1Pizza6-AYW, a circularly permuted designer protein | Descriptor: | SULFATE ION, nv1Pizza6-AYW | Authors: | Mylemans, B, Noguchi, H, Deridder, E, Voet, A.R.D. | Deposit date: | 2018-11-05 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Influence of circular permutations on the structure and stability of a six-fold circular symmetric designer protein. Protein Sci., 2020
|
|
7NKD
| Mycobacterium smegmatis ATP synthase b-delta state 1 | Descriptor: | ATP synthase subunit alpha, ATP synthase subunit b, ATP synthase subunit b-delta, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-11-03 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6I8L
| Crystal structure of Spindlin1 in complex with the inhibitor TD001851a | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-(cyclopropylmethoxy)-6'-[3-(1,3-dihydroisoindol-2-yl)propoxy]spiro[cyclopentane-1,3'-indole]-2'-amine, ... | Authors: | Johansson, C, Fagan, V, Brennan, P.E, Sorrell, F.J, Krojer, T, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. | Deposit date: | 2018-11-20 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019
|
|
2B0M
| Human dihydroorotate dehydrogenase bound to a novel inhibitor | Descriptor: | 3-AMIDO-5-BIPHENYL-BENZOIC ACID, Dihydroorotate dehydrogenase, mitochondrial, ... | Authors: | Hurt, D.E, Sutton, A.E, Clardy, J. | Deposit date: | 2005-09-14 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase. Bioorg.Med.Chem.Lett., 16, 2006
|
|
7NKQ
| Mycobacterium smegmatis ATP synthase b-delta state 3 | Descriptor: | ATP synthase subunit alpha, ATP synthase subunit b, ATP synthase subunit b-delta, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-18 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NKL
| Mycobacterium smegmatis ATP synthase b-delta state 2 | Descriptor: | ATP synthase subunit alpha, ATP synthase subunit b, ATP synthase subunit b-delta, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-18 | Release date: | 2021-11-03 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NJQ
| Mycobacterium smegmatis ATP synthase state 3a | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
5IK4
| Laminin A2LG45 C-form, Apo. | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | Deposit date: | 2016-03-03 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
|
|
7NK7
| Mycobacterium smegmatis ATP synthase F1 state 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.11 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6V9I
| cryo-EM structure of Cullin5 bound to RING-box protein 2 (Cul5-Rbx2) | Descriptor: | Immunoglobulin G-binding protein G,Cullin-5, RING-box protein 2, ZINC ION | Authors: | Komives, E.A, Lumpkin, R.J, Baker, R.W, Leschziner, A.E. | Deposit date: | 2019-12-13 | Release date: | 2020-04-29 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Structure and dynamics of the ASB9 CUL-RING E3 Ligase. Nat Commun, 11, 2020
|
|
7NJP
| Mycobacterium smegmatis ATP synthase state 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8J6J
| Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound with GSK256073 | Descriptor: | 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yuan, Q, Zhu, S, Duan, J, Xu, H.E, Duan, X. | Deposit date: | 2023-04-26 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2. Cell Rep, 42, 2023
|
|
7NJO
| Mycobacterium smegmatis ATP synthase state 1e | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
9EOX
| SARS-CoV2 major protease in covalent complex with a soluble inhibitor. | Descriptor: | 3C-like proteinase nsp5, POTASSIUM ION, Soluble inhibitor | Authors: | Moche, M, Lennerstrand, J, Nyman, T, Strandback, E, Akaberi, D. | Deposit date: | 2024-03-15 | Release date: | 2024-09-04 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries. Antimicrob.Agents Chemother., 68, 2024
|
|
5MCM
| Radiation damage to GH7 Family Cellobiohydrolase from Daphnia pulex: Dose (DWD) 20.6 MGy | Descriptor: | Cellobiohydrolase CHBI, GLYCEROL, SULFATE ION | Authors: | Bury, C.S, McGeehan, J.E, Ebrahim, A, Garman, E.F. | Deposit date: | 2016-11-10 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | OH cleavage from tyrosine: debunking a myth. J Synchrotron Radiat, 24, 2017
|
|