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1NHO
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BU of 1nho by Molmil
Structural and Functional characterization of a Thioredoxin-like Protein from Methanobacterium thermoautotrophicum
Descriptor: Probable Thioredoxin
Authors:Amegbey, G.Y, Monzavi, H, Habibi-Nazhad, B, Bhattacharyya, S, Wishart, D.S.
Deposit date:2002-12-19
Release date:2003-08-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and Functional Characterization of a Thioredoxin-like Protein (Mt0807) from Methanobacterium thermoautotrophicum
Biochemistry, 42, 2003
6RD7
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BU of 6rd7 by Molmil
CryoEM structure of Polytomella F-ATP synthase, c-ring position 1, focussed refinement of Fo and peripheral stalk
Descriptor: ASA-10: Polytomella F-ATP synthase associated subunit 10, ASA-9: Polytomella F-ATP synthase associated subunit 9, ATP synthase associated protein ASA1, ...
Authors:Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W.
Deposit date:2019-04-12
Release date:2019-07-03
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
6UQS
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BU of 6uqs by Molmil
Serendipitous Discovery of Aryl Boronic Acids as beta-Lactamase Inhibitors
Descriptor: 2-hydroxyethyl hydrogen phenylboronate, Beta-lactamase, CHLORIDE ION
Authors:Scapin, G.
Deposit date:2019-10-21
Release date:2019-10-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Serendipitous discovery of aryl boronic acids as beta-lactamase inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
5COV
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BU of 5cov by Molmil
Structure and mechanism of a eukaryal nick-sealing RNA ligase K170M+Mn
Descriptor: MANGANESE (II) ION, Naegleria gruberi RNA ligase
Authors:Unciuleac, M.C, Goldgur, Y, Shuman, S.
Deposit date:2015-07-20
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
5C2M
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BU of 5c2m by Molmil
The de novo evolutionary emergence of a symmetrical protein is shaped by folding constraints
Descriptor: Predicted protein
Authors:Smock, R.G, Yadid, I, Dym, O, Clarke, J, Tawfik, D.S.
Deposit date:2015-06-16
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints.
Cell, 164, 2016
1IT4
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BU of 1it4 by Molmil
Solution structure of the prokaryotic Phospholipase A2 from Streptomyces violaceoruber
Descriptor: CALCIUM ION, phospholipase A2
Authors:Ohtani, K, Sugiyama, M, Izuhara, M, Koike, T.
Deposit date:2002-01-08
Release date:2002-09-04
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:A novel prokaryotic phospholipase A2. Characterization, gene cloning, and solution structure.
J.BIOL.CHEM., 277, 2002
6RD5
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BU of 6rd5 by Molmil
CryoEM structure of Polytomella F-ATP synthase, focussed refinement of Fo and peripheral stalk, C2 symmetry
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ATP synthase associated protein ASA1, ...
Authors:Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W.
Deposit date:2019-04-12
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
1J41
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BU of 1j41 by Molmil
Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed)
Descriptor: BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ...
Authors:Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-02-21
Release date:2003-07-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Direct observation of photolysis-induced tertiary structural changes in hemoglobin
Proc.Natl.Acad.Sci.USA, 100, 2003
6X2A
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BU of 6x2a by Molmil
SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X29
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BU of 6x29 by Molmil
SARS-CoV-2 rS2d Down State Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
3AKB
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BU of 3akb by Molmil
Structural basis for prokaryotic calcium-mediated regulation by a Streptomyces coelicolor calcium-binding protein
Descriptor: CALCIUM ION, Putative calcium binding protein
Authors:Zhao, X, Pang, H, Wang, S, Zhou, W, Yang, K, Bartlam, M.
Deposit date:2010-07-09
Release date:2011-01-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium binding protein
Protein Cell, 1, 2010
1YYZ
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BU of 1yyz by Molmil
R-State AMP Complex Reveals Initial Steps of the Quaternary Transition of Fructose-1,6-bisphosphatase
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase, ...
Authors:Iancu, C.V, Mukund, S, Fromm, H.J, Honzatko, R.B.
Deposit date:2005-02-25
Release date:2005-03-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:R-state AMP complex reveals initial steps of the quaternary transition of fructose-1,6-bisphosphatase.
J.Biol.Chem., 280, 2005
1J3Y
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BU of 1j3y by Molmil
Direct observation of photolysis-induced tertiary structural changes in human hemoglobin; Crystal structure of alpha(Fe)-beta(Ni) hemoglobin (laser photolysed)
Descriptor: BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ...
Authors:Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-02-21
Release date:2003-07-22
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Direct observation of photolysis-induced tertiary structural changes in hemoglobin
Proc.Natl.Acad.Sci.USA, 100, 2003
3AKA
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BU of 3aka by Molmil
Structural basis for prokaryotic calcium-mediated regulation by a Streptomyces coelicolor calcium-binding protein
Descriptor: CALCIUM ION, Putative calcium binding protein
Authors:Zhao, X, Pang, H, Wang, S, Zhou, W, Yang, K, Bartlam, M.
Deposit date:2010-07-09
Release date:2011-01-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium binding protein
Protein Cell, 1, 2010
5L44
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BU of 5l44 by Molmil
Structure of K-26-DCP in complex with the K-26 tripeptide
Descriptor: K-26 dipeptidyl carboxypeptidase, MAGNESIUM ION, N-ACETYL-L-ILE-L-TYR-(R)-1-AMINO-2-(4-HYDROXYPHENYL)ETHYLPHOSPHONIC ACID, ...
Authors:Masuyer, G, Acharya, K.R, Kramer, G.J, Bachmann, B.O.
Deposit date:2016-05-24
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor.
FEBS J., 283, 2016
3HFV
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BU of 3hfv by Molmil
Crystal structure of human mitochondrial phenylalanyl-tRNA synthetase complexed with m-tyrosine
Descriptor: META-TYROSINE, Phenylalanyl-tRNA synthetase, mitochondrial
Authors:Klipcan, L, Moor, N, Kessler, N, Safro, M.G.
Deposit date:2009-05-12
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
3HFZ
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BU of 3hfz by Molmil
Crystal structure of Thermus thermophilus Phenylalanyl-tRNA synthetase complexed with m-tyrosine
Descriptor: META-TYROSINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain
Authors:Klipcan, L, Moor, N, Kessler, N, Safro, M.G.
Deposit date:2009-05-13
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
9GKT
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BU of 9gkt by Molmil
Crystal structure of artificial enzyme LmrR_pAF variant RGN
Descriptor: Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H, Leveson-Gower, R.B, Rozeboom, H.J, Roelfes, G.
Deposit date:2024-08-26
Release date:2025-02-26
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Evolutionary Specialization of a Promiscuous Designer Enzyme.
Acs Catalysis, 15, 2025
9GKR
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BU of 9gkr by Molmil
Crystal structure of artificial enzyme LmrR_pAF variant RMH in crystal form 1
Descriptor: Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H, Leveson-Gower, R.B, Rozeboom, H.J, Roelfes, G.
Deposit date:2024-08-26
Release date:2025-02-26
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Evolutionary Specialization of a Promiscuous Designer Enzyme.
Acs Catalysis, 15, 2025
9GKS
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BU of 9gks by Molmil
Crystal structure of artificial enzyme LmrR_pAF variant RMH in crystal form 2
Descriptor: Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H, Leveson-Gower, R.B, Rozeboom, H.J, Roelfes, G.
Deposit date:2024-08-26
Release date:2025-02-26
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Evolutionary Specialization of a Promiscuous Designer Enzyme.
Acs Catalysis, 15, 2025
1H6F
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BU of 1h6f by Molmil
Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site
Descriptor: 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX3
Authors:Coll, M, Muller, C.W.
Deposit date:2001-06-13
Release date:2002-04-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome
Structure, 10, 2002
5L43
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BU of 5l43 by Molmil
Structure of K26-DCP
Descriptor: K-26 dipeptidyl carboxypeptidase, MAGNESIUM ION, SULFATE ION, ...
Authors:Masuyer, G, Acharya, K.R, Kramer, G.J, Bachmann, B.O.
Deposit date:2016-05-24
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor.
FEBS J., 283, 2016
9E7C
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BU of 9e7c by Molmil
TRK-fused Gene (TFG) PB1 Domain D60A/D62R Variant
Descriptor: Protein TFG
Authors:Schuh, A.L, Bhattacharyya, B, Keck, J.L, Audhya, A.
Deposit date:2024-11-01
Release date:2024-11-20
Last modified:2024-12-04
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Multiple roles for TFG ring complexes in neuronal cargo trafficking.
Biorxiv, 2024
9DBO
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BU of 9dbo by Molmil
Crystal structure of a synthetic Fab (R3E9) in complex with the FRB domain of mTOR
Descriptor: Fab heavy chain, Fab light chain, Serine/threonine-protein kinase mTOR
Authors:O'Leary, K.M, Slezak, T, Kossiakoff, A.A.
Deposit date:2024-08-23
Release date:2025-06-11
Last modified:2025-06-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Conformation-specific synthetic intrabodies modulate mTOR signaling with subcellular spatial resolution.
Proc.Natl.Acad.Sci.USA, 122, 2025
9DL0
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BU of 9dl0 by Molmil
Crystal structure of a synthetic Fab (R3H8) in complex with the FRB domain of mTOR
Descriptor: Fab heavy chain, Fab light chain, Serine/threonine-protein kinase mTOR
Authors:O'Leary, K.M, Slezak, T, Kossiakoff, A.A.
Deposit date:2024-09-10
Release date:2025-06-11
Last modified:2025-06-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformation-specific synthetic intrabodies modulate mTOR signaling with subcellular spatial resolution.
Proc.Natl.Acad.Sci.USA, 122, 2025

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數據於2025-07-23公開中

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