PDB: 12060 resultsInfo pagesStatus searchChemie searchBIRD

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4ATM	Crystal structure of the BAR domain of human Amphiphysin, isoform 1 at 1.8 Angstrom resolution featuring increased order at the N- terminus. Descriptor: 1,2-ETHANEDIOL, AMPHIPHYSIN, GLYCEROL Authors: Allerston, C.K, Krojer, T, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O. Deposit date: 2012-05-08 Release date: 2012-05-30 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.783 Å) Cite: Crystal Structure of the Bar Domain of Human Amphiphysin, Isoform 1 To be Published
7ATM	Structure of P. aeruginosa PBP3 in complex with a phenyl boronic acid (Compound 1) Descriptor: (3-(1H-tetrazol-5-yl)phenyl)boronic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Newman, H, Bellini, B, Dowson, C.G. Deposit date: 2020-10-30 Release date: 2021-08-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.582 Å) Cite: High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes. J.Med.Chem., 64, 2021
8ATO	Structure of the giant inhibitor of apoptosis, BIRC6 bound to the regulator SMAC Descriptor: Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein Authors: Dietz, L, Elliott, P.R. Deposit date: 2022-08-23 Release date: 2023-03-08 Last modified: 2023-03-29 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science, 379, 2023
6ATM	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox Descriptor: Potassium channel toxin alpha-KTx 3.10 Authors: Gewe, M.M, Rupert, P, Strong, R.K. Deposit date: 2017-08-29 Release date: 2018-08-22 Last modified: 2019-11-06 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox To Be Published
6RPE	Structure of 5% reduced KpDyP in complex with cyanide Descriptor: CYANIDE ION, GLYCEROL, Iron-dependent peroxidase, ... Authors: Pfanzagl, V, Beale, J, Hofbauer, S. Deposit date: 2019-05-14 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner. J.Biol.Chem., 295, 2020
6RR5	Structure of 50% reduced KpDyP Descriptor: GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... Authors: Pfanzagl, V, Beale, J, Hofbauer, S. Deposit date: 2019-05-17 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner. J.Biol.Chem., 295, 2020
6RPD	Structure of ferrous KpDyP in complex with cyanide Descriptor: CYANIDE ION, GLYCEROL, Iron-dependent peroxidase, ... Authors: Pfanzagl, V, Beale, J, Hofbauer, S. Deposit date: 2019-05-14 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.52 Å) Cite: X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner. J.Biol.Chem., 295, 2020
1MAP	CRYSTAL STRUCTURES OF TRUE ENZYMATIC REACTION INTERMEDIATES: ASPARTATE AND GLUTAMATE KETIMINES IN ASPARTATE AMINOTRANSFERASE Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE Authors: Malashkevich, V.N, Jansonius, J.N. Deposit date: 1993-09-10 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase. Biochemistry, 32, 1993
1MAQ	CRYSTAL STRUCTURES OF TRUE ENZYMATIC REACTION INTERMEDIATES: ASPARTATE AND GLUTAMATE KETIMINES IN ASPARTATE AMINOTRANSFERASE Descriptor: ASPARTATE AMINOTRANSFERASE, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid Authors: Malashkevich, V.N, Jansonius, J.N. Deposit date: 1993-09-10 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase. Biochemistry, 32, 1993
1AMA	DOMAIN CLOSURE IN MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE Authors: Vincent, M.G, Genovesio-Taverne, J.-C, Jansonius, J.N. Deposit date: 1992-02-05 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Domain closure in mitochondrial aspartate aminotransferase. J.Mol.Biol., 227, 1992
1AKB	STRUCTURAL BASIS FOR THE CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE K258H LACKING ITS PYRIDOXAL-5'-PHOSPHATE-BINDING LYSINE RESIDUE Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE Authors: Malashkevich, V.N, Jansonius, J.N. Deposit date: 1994-02-28 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry, 34, 1995
1AKA	STRUCTURAL BASIS FOR THE CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE K258H LACKING ITS PYRIDOXAL-5'-PHOSPHATE-BINDING LYSINE RESIDUE Descriptor: ASPARTATE AMINOTRANSFERASE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE Authors: Malashkevich, V.N, Jansonius, J.N. Deposit date: 1994-02-28 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry, 34, 1995
1AKC	Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking its pyridoxal-5'-phosphate-binding lysine residue Descriptor: 4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM, ASPARTATE AMINOTRANSFERASE Authors: Malashkevich, V.N, Jansonius, J.N. Deposit date: 1994-02-28 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry, 34, 1995
1TAS	CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE Authors: Hohenester, E, Jansonius, J.N. Deposit date: 1993-10-04 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystalline mitochondrial aspartate aminotransferase exists in only two conformations. J.Mol.Biol., 236, 1994
1TAT	CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Hohenester, E, Jansonius, J.N. Deposit date: 1993-10-04 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystalline mitochondrial aspartate aminotransferase exists in only two conformations. J.Mol.Biol., 236, 1994
1TAR	CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Hohenester, E, Jansonius, J.N. Deposit date: 1993-10-04 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystalline mitochondrial aspartate aminotransferase exists in only two conformations. J.Mol.Biol., 236, 1994
1OXO	ASPARTATE AMINOTRANSFERASE, H-ASP COMPLEX, OPEN CONFORMATION Descriptor: 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE Authors: Hohenester, E, Schirmer, T, Jansonius, J.N. Deposit date: 1995-12-23 Release date: 1996-06-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase. Eur.J.Biochem., 236, 1996
1OXP	ASPARTATE AMINOTRANSFERASE, H-ASP COMPLEX, CLOSED CONFORMATION Descriptor: 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE Authors: Hohenester, E, Schirmer, T, Jansonius, J.N. Deposit date: 1995-12-23 Release date: 1996-06-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase. Eur.J.Biochem., 236, 1996
1JDX	CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH L-NORVALINE Descriptor: NORVALINE, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE) Authors: Fritsche, E, Humm, A, Huber, R. Deposit date: 1998-10-12 Release date: 1999-02-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study. J.Biol.Chem., 274, 1999
1FH0	CRYSTAL STRUCTURE OF HUMAN CATHEPSIN V COMPLEXED WITH AN IRREVERSIBLE VINYL SULFONE INHIBITOR Descriptor: CATHEPSIN V, Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide, SULFATE ION Authors: Somoza, J.R. Deposit date: 2000-07-30 Release date: 2001-07-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of human cathepsin V. Biochemistry, 39, 2000
1JDW	CRYSTAL STRUCTURE AND MECHANISM OF L-ARGININE: GLYCINE AMIDINOTRANSFERASE: A MITOCHONDRIAL ENZYME INVOLVED IN CREATINE BIOSYNTHESIS Descriptor: BETA-MERCAPTOETHANOL, L-ARGININE:GLYCINE AMIDINOTRANSFERASE Authors: Humm, A, Fritsche, E, Steinbacher, S, Huber, R. Deposit date: 1997-01-22 Release date: 1998-01-28 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis. EMBO J., 16, 1997
1IVR	STRUCTURE OF ASPARTATE AMINOTRANSFERASE Descriptor: ASPARTATE AMINOTRANSFERASE, N-PYRIDOXYL-2,3-DIHYDROXYASPARTIC ACID-5-MONOPHOSPHATE Authors: Graf Von Stosch, A. Deposit date: 1996-10-11 Release date: 1997-07-23 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Aspartate aminotransferase complexed with erythro-beta-hydroxyaspartate: crystallographic and spectroscopic identification of the carbinolamine intermediate. Biochemistry, 35, 1996
7AAT	X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Mcphalen, C.A, Vincent, M.G, Jansonius, J.N. Deposit date: 1991-12-02 Release date: 1993-10-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J.Mol.Biol., 225, 1992
6RQY	Structure of % reduced KpDyP Descriptor: GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... Authors: Pfanzagl, V, Beale, J, Hofbauer, S. Deposit date: 2019-05-16 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner. J.Biol.Chem., 295, 2020
6RR6	Structure of 100% reduced KpDyP Descriptor: GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... Authors: Pfanzagl, V, Beale, J, Hofbauer, S. Deposit date: 2019-05-17 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner. J.Biol.Chem., 295, 2020

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