6R5Q
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![BU of 6r5q by Molmil](/molmil-images/mine/6r5q) | Structure of XBP1u-paused ribosome nascent chain complex (post-state) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2019-03-25 | Release date: | 2019-07-10 | Last modified: | 2019-10-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6RAX
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![BU of 6rax by Molmil](/molmil-images/mine/6rax) | D. melanogaster CMG-DNA, State 1B | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-11 | Last modified: | 2019-09-18 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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7CXY
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![BU of 7cxy by Molmil](/molmil-images/mine/7cxy) | Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (zinc-bound form) | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | Deposit date: | 2020-09-02 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7NPR
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![BU of 7npr by Molmil](/molmil-images/mine/7npr) | Structure of an intact ESX-5 inner membrane complex, Composite C3 model | Descriptor: | ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ... | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7SN2
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![BU of 7sn2 by Molmil](/molmil-images/mine/7sn2) | Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pan, J, Abraham, J, Yang, P, Shankar, S. | Deposit date: | 2021-10-27 | Release date: | 2021-12-08 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
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7DQV
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![BU of 7dqv by Molmil](/molmil-images/mine/7dqv) | Crystal structure of a CmABCB1 mutant | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, MAGNESIUM ION, NITRATE ION, ... | Authors: | Matsuoka, K, Nakatsu, T, Kato, H. | Deposit date: | 2020-12-24 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The crystal structure of the CmABCB1 G132V mutant, which favors the outward-facing state, reveals the mechanism of the pivotal joint between TM1 and TM3. Protein Sci., 30, 2021
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7DRQ
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![BU of 7drq by Molmil](/molmil-images/mine/7drq) | Crystal structure of polysaccharide lyase Uly1 | Descriptor: | CALCIUM ION, Uly1 | Authors: | Chen, X.L, Cao, H.Y, Xu, F, Dong, F. | Deposit date: | 2020-12-29 | Release date: | 2021-03-31 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Mechanistic Insights into Substrate Recognition and Catalysis of a New Ulvan Lyase of Polysaccharide Lyase Family 24. Appl.Environ.Microbiol., 87, 2021
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7CXX
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![BU of 7cxx by Molmil](/molmil-images/mine/7cxx) | Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (disulfide-bonded form) | Descriptor: | ACETATE ION, Carbonic anhydrase, SULFATE ION | Authors: | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | Deposit date: | 2020-09-02 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7CXW
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![BU of 7cxw by Molmil](/molmil-images/mine/7cxw) | Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (C116 flipped form) | Descriptor: | ACETATE ION, Carbonic anhydrase | Authors: | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | Deposit date: | 2020-09-02 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7D2V
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![BU of 7d2v by Molmil](/molmil-images/mine/7d2v) | Crystal Structure of BACE1 in complex with N-{3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide | Descriptor: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | Authors: | Fujimoto, K, Yoshida, S, Tadano, G, Asada, N, Fuchino, K, Suzuki, S, Matsuoka, E, Yamamoto, T, Yamamoto, S, Ando, S, Kanegawa, N, Tonomura, Y, Ito, H, Moechars, D, Rombouts, F.J.R, Gijsen, H.J.M, Kusakabe, K.I. | Deposit date: | 2020-09-17 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective beta-Secretase (BACE1) Inhibitors over BACE2. J.Med.Chem., 64, 2021
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6RAL
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![BU of 6ral by Molmil](/molmil-images/mine/6ral) | Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAY
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![BU of 6ray by Molmil](/molmil-images/mine/6ray) | D. melanogaster CMG-DNA, State 2A | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-11 | Last modified: | 2019-09-18 | Method: | ELECTRON MICROSCOPY (4.28 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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7DDW
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![BU of 7ddw by Molmil](/molmil-images/mine/7ddw) | Crystal structure of a mutant Staphylococcus equorum manganese superoxide dismutase S126C | Descriptor: | MANGANESE (II) ION, Superoxide dismutase | Authors: | Retnoningrum, D.S, Yoshida, H, Razani, M.D, Meidianto, V.F, Hartanto, A, Artarini, A, Ismaya, W.T. | Deposit date: | 2020-10-30 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | The role of S126 in the Staphylococcus equorum MnSOD activity and stability. J.Struct.Biol., 213, 2021
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7DJ1
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![BU of 7dj1 by Molmil](/molmil-images/mine/7dj1) | Crystal structure of the G26C mutant of LeuT | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.528 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7DII
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![BU of 7dii by Molmil](/molmil-images/mine/7dii) | Crystal structure of LeuT in lipidic cubic phase at pH 7 | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7DIX
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![BU of 7dix by Molmil](/molmil-images/mine/7dix) | Crystal structure of LeuT in lipidic cubic phase at pH 5 | Descriptor: | Na(+):neurotransmitter symporter (Snf family), SELENOMETHIONINE, SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7D2E
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![BU of 7d2e by Molmil](/molmil-images/mine/7d2e) | Tetrameric coiled-coil structure of liprin-alpha2_H3 | Descriptor: | Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
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6R84
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![BU of 6r84 by Molmil](/molmil-images/mine/6r84) | Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | Deposit date: | 2019-03-31 | Release date: | 2019-06-26 | Last modified: | 2019-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature, 570, 2019
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4G26
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![BU of 4g26 by Molmil](/molmil-images/mine/4g26) | Crystal Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana with Ca | Descriptor: | CALCIUM ION, Pentatricopeptide repeat-containing protein At2g32230, mitochondrial, ... | Authors: | Koutmos, M, Howard, M.J, Fierke, C.A. | Deposit date: | 2012-07-11 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing. Proc.Natl.Acad.Sci.USA, 109, 2012
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7CZH
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![BU of 7czh by Molmil](/molmil-images/mine/7czh) | PL24 ulvan lyase-Uly1 | Descriptor: | CALCIUM ION, GLYCEROL, Uly1 | Authors: | Zhang, Y.Z, Chen, X.L, Dong, F, Xu, F. | Deposit date: | 2020-09-08 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Mechanistic Insights into Substrate Recognition and Catalysis of a New Ulvan Lyase of Polysaccharide Lyase Family 24. Appl.Environ.Microbiol., 87, 2021
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7NKU
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![BU of 7nku by Molmil](/molmil-images/mine/7nku) | diazaborine bound Drg1(AFG2) | Descriptor: | 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL, ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Prattes, M, Bergler, H, Haselbach, D. | Deposit date: | 2021-02-19 | Release date: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nat Commun, 12, 2021
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7D2H
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![BU of 7d2h by Molmil](/molmil-images/mine/7d2h) | Tetrameric coiled-coil structure of liprin-alpha2_H2 | Descriptor: | GLYCEROL, Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
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6RCQ
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![BU of 6rcq by Molmil](/molmil-images/mine/6rcq) | PfRH5-binding monoclonal antibody R5.011 | Descriptor: | ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... | Authors: | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | Deposit date: | 2019-04-11 | Release date: | 2019-06-26 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
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6RCS
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![BU of 6rcs by Molmil](/molmil-images/mine/6rcs) | PfRH5-binding monoclonal antibody R5.016 | Descriptor: | ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... | Authors: | Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. | Deposit date: | 2019-04-11 | Release date: | 2019-06-26 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
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7D35
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![BU of 7d35 by Molmil](/molmil-images/mine/7d35) | Human LC8 bound to ebola virus VP35(67-76) | Descriptor: | Dynein light chain 1, cytoplasmic, Peptide from Polymerase cofactor VP35 | Authors: | Ku, B, Lim, D. | Deposit date: | 2020-09-18 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Crystal structure of human LC8 bound to a peptide from Ebola virus VP35. J.Microbiol, 59, 2021
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