5R2D
| PanDDA analysis group deposition -- Endothiapepsin in complex with fragment F2X-Entry H11, DMSO-free | Descriptor: | 1-cyclopentyl-3-[[(2~{S})-oxolan-2-yl]methyl]urea, Endothiapepsin | Authors: | Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. | Deposit date: | 2020-02-13 | Release date: | 2020-06-03 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (0.919 Å) | Cite: | F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
|
|
3B60
| Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form | Descriptor: | Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
3FBR
| structure of HipA-amppnp-peptide | Descriptor: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu | Authors: | Schumacher, M.A. | Deposit date: | 2008-11-19 | Release date: | 2009-02-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009
|
|
1MY4
| crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form | Descriptor: | 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
|
|
3B5Y
| Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP | Descriptor: | Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
3FFB
| Gi-alpha-1 mutant in GDP bound form | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | Authors: | Chauhan, R, Kapoor, N. | Deposit date: | 2008-12-02 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural evidence for a sequential release mechanism for activation of heterotrimeric g proteins. J.Mol.Biol., 393, 2009
|
|
1Y2K
| Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester | Descriptor: | 1,2-ETHANEDIOL, 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ... | Authors: | Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design Nat.Biotechnol., 23, 2005
|
|
1QGZ
| FERREDOXIN:NADP+ REDUCTASE MUTANT WITH LEU 78 REPLACED BY ASP (L78D) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (FERREDOXIN:NADP+ REDUCTASE), SULFATE ION | Authors: | Hermoso, J.A, Mayoral, T, Medina, M, Sanz-Aparicio, J, Gomez-Moreno, C. | Deposit date: | 1999-05-10 | Release date: | 2002-02-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of a cluster of hydrophobic residues near the FAD cofactor in Anabaena PCC 7119 ferredoxin-NADP+ reductase for optimal complex formation and electron transfer to ferredoxin. J.Biol.Chem., 276, 2001
|
|
1QH0
| FERREDOXIN:NADP+ REDUCTASE MUTANT WITH LEU 76 MUTATED BY ASP AND LEU 78 MUTATED BY ASP | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (FERREDOXIN:NADP+ REDUCTASE), SULFATE ION | Authors: | Hermoso, J.A, Mayoral, T, Medina, M, Martinez-Ripoll, M, Martinez-Julvez, M, Sanz-Aparicio, J, Gomez-Moreno, C. | Deposit date: | 1999-05-10 | Release date: | 2002-02-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Role of a cluster of hydrophobic residues near the FAD cofactor in Anabaena PCC 7119 ferredoxin-NADP+ reductase for optimal complex formation and electron transfer to ferredoxin. J.Biol.Chem., 276, 2001
|
|
3C3Q
| ALIX Bro1-domain:CHMIP4B co-crystal structure | Descriptor: | Charged multivesicular body protein 4b peptide, GLYCEROL, Programmed cell death 6-interacting protein | Authors: | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | Deposit date: | 2008-01-28 | Release date: | 2008-06-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
1YTR
| NMR structure of plantaricin a in dpc micelles, 20 structures | Descriptor: | Bacteriocin plantaricin A | Authors: | Kristiansen, P.E, Fimland, G, Mantzilas, D, Nissen-Meyer, J. | Deposit date: | 2005-02-11 | Release date: | 2005-05-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and mode of action of the membrane-permeabilizing antimicrobial peptide pheromone plantaricin A J.Biol.Chem., 280, 2005
|
|
2PUP
| |
1ZYD
| Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type Complexed with ATP. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase GCN2 | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | Deposit date: | 2005-06-09 | Release date: | 2005-06-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2 J.Biol.Chem., 280, 2005
|
|
2PU8
| |
2PUI
| |
5WOT
| |
3GU4
| |
5WOY
| |
4XH5
| Crystal structure of Salmonella typhimurium propionate kinase A88G mutant, in complex with AMPPNP and propionate | Descriptor: | GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROPANOIC ACID, ... | Authors: | Murthy, A.M, Mathivanan, S, Chittori, S, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2015-01-04 | Release date: | 2015-09-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structures of substrate- and nucleotide-bound propionate kinase from Salmonella typhimurium: substrate specificity and phosphate-transfer mechanism Acta Crystallogr.,Sect.D, 71, 2015
|
|
1DJC
| |
7QI2
| |
1DAW
| CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN KINASE CK2 | Authors: | Niefind, K, Puetter, M, Guerra, B, Issinger, O.G, Schomburg, D. | Deposit date: | 1999-11-01 | Release date: | 2000-05-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | GTP plus water mimic ATP in the active site of protein kinase CK2. Nat.Struct.Biol., 6, 1999
|
|
4XH4
| Crystal structure of Salmonella typhimurium propionate kinase A88V mutant, in complex with AMPPNP and propionate | Descriptor: | GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROPANOIC ACID, ... | Authors: | Murthy, A.M.V, Mathivanan, S, Chittori, S, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2015-01-04 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of substrate- and nucleotide-bound propionate kinase from Salmonella typhimurium: substrate specificity and phosphate-transfer mechanism Acta Crystallogr.,Sect.D, 71, 2015
|
|
4QXO
| Crystal structure of hSTING(group2) in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2014-07-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Cell Rep, 8, 2014
|
|
7M12
| TVV2 capsid protein | Descriptor: | Capsid protein | Authors: | Zhou, H.Z, Stevens, A.W, Cui, Y.X, Muratore, K.A, Johnson, P.J. | Deposit date: | 2021-03-12 | Release date: | 2021-04-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Atomic Structure of the Trichomonas vaginalis Double-Stranded RNA Virus 2. Mbio, 12, 2021
|
|