PDB: 42053 resultsInfo pagesStatus searchChemie searchBIRD

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5HPU	Insulin with proline analog HyP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin, chain A, ... Authors: Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. Deposit date: 2016-01-21 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
4B0H	B. subtilis dUTPase YncF in complex with dU, PPi and Mg b (P212121) Descriptor: 2'-DEOXYURIDINE, CHLORIDE ION, MAGNESIUM ION, ... Authors: Timm, J, Garcia-Nafria, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. Deposit date: 2012-07-02 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism Acta Crystallogr.,Sect.D, 69, 2013
3LXO	The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate Descriptor: Ribonuclease pancreatic, THYMIDINE-3'-PHOSPHATE Authors: Doucet, N, Jayasundera, T.B, Simonovic, M, Loria, J.P. Deposit date: 2010-02-25 Release date: 2010-04-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.549 Å) Cite: The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding. Proteins, 78, 2010
5H7J	Crystal structure of Elongation factor 2 Descriptor: Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER Authors: Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. Deposit date: 2016-11-18 Release date: 2018-02-21 Last modified: 2018-05-02 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion Nucleic Acids Res., 46, 2018
5YYC	Crystal structure of alanine racemase from Bacillus pseudofirmus (OF4) Descriptor: Alanine racemase, PYRIDOXAL-5'-PHOSPHATE Authors: Dong, H, Hu, T.T, He, G.Z, Lu, D.R, Qi, J.X, Dou, Y.S, Long, W, He, X, Su, D, Ju, J.S. Deposit date: 2017-12-08 Release date: 2019-01-02 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Structural features and kinetic characterization of alanine racemase from Bacillus pseudofirmus OF4. Biochem. Biophys. Res. Commun., 497, 2018
7RY1	human Hsp90_MC domain structure Descriptor: Heat shock protein HSP 90-alpha, N-[2-(1-MALEIMIDYL)ETHYL]-7-DIETHYLAMINOCOUMARIN-3-CARBOXAMIDE Authors: Peng, S, Deng, J, Matts, R. Deposit date: 2021-08-24 Release date: 2022-05-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.523 Å) Cite: Crystal structure of the middle and C-terminal domains of Hsp90 alpha labeled with a coumarin derivative reveals a potential allosteric binding site as a drug target. Acta Crystallogr D Struct Biol, 78, 2022
5HVS	Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Biaryltriazole Inhibitor (3i-305) Descriptor: 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ... Authors: Robertson, M.J, Jorgensen, W.L. Deposit date: 2016-01-28 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
2Z6D	Crystal structure of LOV1 domain of phototropin2 from Arabidopsis thaliana Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2 Authors: Nakasako, M, Matsuoka, D, Tokutomi, S. Deposit date: 2007-07-29 Release date: 2008-07-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis of the LOV1 dimerization of Arabidopsis phototropins 1 and 2 J.Mol.Biol., 381, 2008
5ZBZ	Crystal structure of the DEAD domain of Human eIF4A with sanguinarine Descriptor: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Eukaryotic initiation factor 4A-I, MALONATE ION Authors: Ding, Y, Ding, L. Deposit date: 2018-02-14 Release date: 2019-02-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.30860257 Å) Cite: Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling. Cell Chem Biol, 26, 2019
5X4U	PAC from Oscillatoriaacuminata after 60 seconds photoactivation Descriptor: FLAVIN MONONUCLEOTIDE, Photoactivated adenylyl cyclase Authors: Ohki, M, Park, S.-Y. Deposit date: 2017-02-14 Release date: 2017-07-26 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Molecular mechanism of photoactivation of a light-regulated adenylate cyclase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Z37	Crystal Structure of Abrin A chain (Recombinant) at 1.3 Angstroms Descriptor: Abrin A-chain, IMIDAZOLE Authors: Bansia, H, Karande, A.A, Ramakumar, S. Deposit date: 2018-01-05 Release date: 2019-01-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structural basis for neutralization of cytotoxic abrin by monoclonal antibody D6F10. FEBS J., 286, 2019
5ZII	Crystal Structures of Mutant Endo-beta-1,4-xylanase II (Y88F)Complexed with Xylotriose Descriptor: Endo-1,4-beta-xylanase 2, IODIDE ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose Authors: Zhang, X, Wan, Q. Deposit date: 2018-03-15 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal Structures of Endo-beta-1,4-xylanase II to be published
4BI0	Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor Descriptor: 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 5H-pyrimido[5,4-b]indole, ... Authors: Langdon, S.R, Westwood, I.M, van Montfort, R.L.M, Brown, N, Blagg, J. Deposit date: 2013-04-09 Release date: 2013-05-22 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Scaffold-Focused Virtual Screening: Prospective Application to the Discovery of Ttk Inhibitors. J.Chem.Inf.Model, 53, 2013
5HCI	GPN-loop GTPase Npa3 in complex with GDP Descriptor: GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. Deposit date: 2016-01-04 Release date: 2016-01-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
7S3A	Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit Authors: Jenkins, J.L, Henderson, S, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3B	Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Jenkins, J.L, Henderson, S, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
4KYN	Crystal structure of odorant binding protein 48 from Anopheles gambiae at 3.3 Angstrom resolution Descriptor: Odorant binding protein-8 Authors: Tsitsanou, K.E, Drakou, C.E, Zographos, S.E. Deposit date: 2013-05-29 Release date: 2013-10-16 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal and Solution Studies of the "Plus-C" Odorant-binding Protein 48 from Anopheles gambiae: CONTROL OF BINDING SPECIFICITY THROUGH THREE-DIMENSIONAL DOMAIN SWAPPING. J.Biol.Chem., 288, 2013
3LYQ	Crystal structure of IpgB2 from Shigella flexneri Descriptor: CITRATE ANION, IpgB2, MU-OXO-DIIRON Authors: Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. Deposit date: 2010-02-28 Release date: 2010-03-31 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
7S3C	Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Glasser, E, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7NXZ	Synthetic glycoform of Human Interleukin 6 Descriptor: Interleukin-6 Authors: Weyand, M, Unverzagt, C. Deposit date: 2021-03-19 Release date: 2021-04-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.998 Å) Cite: Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance. Angew.Chem.Int.Ed.Engl., 60, 2021
3LX1	Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535 Descriptor: DNA polymerase sliding clamp 1, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
6DHZ	Crystallographic octamer of a metal-free RIDC1 variant bearing two disulfide bonded cysteines Descriptor: CALCIUM ION, HEME C, Soluble cytochrome b562 Authors: Tezcan, F.A, Churchfield, L.A. Deposit date: 2018-05-21 Release date: 2018-07-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Determining the Structural and Energetic Basis of Allostery in a De Novo Designed Metalloprotein Assembly. J. Am. Chem. Soc., 140, 2018
3LY7	Crystal structure of the periplasmic domain of CadC Descriptor: Transcriptional activator cadC Authors: Eichinger, A, Skerra, A. Deposit date: 2010-02-26 Release date: 2011-02-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family. Protein Sci., 20, 2011
5HDI	Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450 Descriptor: Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE Authors: Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D. Deposit date: 2016-01-05 Release date: 2016-05-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis. Sci Rep, 6, 2016
5ZO5	active state of the nuclease Descriptor: MANGANESE (II) ION, Putative 3'-5' exonuclease family protein, SULFATE ION Authors: Yuan, Z.L, Gu, L.C. Deposit date: 2018-04-12 Release date: 2019-04-10 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.297 Å) Cite: NrnC, an RNase D-Like Protein FromAgrobacterium, Is a Novel Octameric Nuclease That Specifically Degrades dsDNA but Leaves dsRNA Intact. Front Microbiol, 9, 2018

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