3GOK
| Binding site mapping of protein ligands | Descriptor: | 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP kinase-activated protein kinase 2 | Authors: | Scheich, C. | Deposit date: | 2009-03-19 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Binding site mapping of protein ligands To be published
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1WDX
| Yeast BBC1 SH3 domain, triclinic crystal form | Descriptor: | Myosin tail region-interacting protein MTI1 | Authors: | Wilmanns, M, Consani Textor, L, Kursula, P, Kursula, I, Lehmann, F, Song, Y.H. | Deposit date: | 2004-05-19 | Release date: | 2005-05-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Yeast BBC1 SH3 domain, triclinic crystal form To be Published
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1J41
| Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed) | Descriptor: | BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ... | Authors: | Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-02-21 | Release date: | 2003-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Direct observation of photolysis-induced tertiary structural changes in hemoglobin Proc.Natl.Acad.Sci.USA, 100, 2003
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2QR7
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1X48
| Solution structure of the second DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase | Authors: | He, F, Muto, Y, Inoue, M, Tarada, T, Shirouzu, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-14 | Release date: | 2005-11-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the second DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase To be Published
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1IR7
| IM mutant of lysozyme | Descriptor: | lysozyme | Authors: | Ohmura, T, Ueda, T, Hashimoto, Y, Imoto, T. | Deposit date: | 2001-09-19 | Release date: | 2001-10-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tolerance of point substitution of methionine for isoleucine in hen egg white lysozyme. Protein Eng., 14, 2001
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1IR9
| IM mutant of lysozyme | Descriptor: | lysozyme | Authors: | Ohmura, T, Ueda, T, Hashimoto, Y, Imoto, T. | Deposit date: | 2001-09-19 | Release date: | 2001-10-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tolerance of point substitution of methionine for isoleucine in hen egg white lysozyme. Protein Eng., 14, 2001
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1X5H
| The solution structure of the third fibronectin type III domain of human Neogenin | Descriptor: | Neogenin | Authors: | Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-15 | Release date: | 2005-11-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of the third fibronectin type III domain of human Neogenin To be Published
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1X5X
| Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3 | Descriptor: | Fibronectin type-III domain containing protein 3a | Authors: | Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-17 | Release date: | 2005-11-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3 To be Published
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1IP4
| G72A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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1IRV
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1WBO
| fragment based p38 inhibitors | Descriptor: | 2-CHLOROPHENOL, MITOGEN-ACTIVATED PROTEIN KINASE 14 | Authors: | Cleasby, A, Devine, L, Gill, A, Jhoti, H. | Deposit date: | 2004-11-04 | Release date: | 2005-01-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48, 2005
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1WBW
| Identification of novel p38 alpha MAP Kinase inhibitors using fragment-based lead generation. | Descriptor: | 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE, MITOGEN-ACTIVATED PROTEIN KINASE 14 | Authors: | Tickle, J, Cleasby, A, Devine, L.A, Jhoti, H. | Deposit date: | 2004-11-05 | Release date: | 2005-11-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Identification of Novel P38Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation J.Med.Chem., 48, 2005
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1IRH
| The Solution Structure of The Third Kunitz Domain of Tissue Factor Pathway Inhibitor | Descriptor: | tissue factor pathway inhibitor | Authors: | Mine, S, Yamazaki, T, Miyata, T, Hara, S, Kato, H. | Deposit date: | 2001-10-02 | Release date: | 2002-02-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor. Biochemistry, 41, 2002
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1IS0
| Crystal Structure of a Complex of the Src SH2 Domain with Conformationally Constrained Peptide Inhibitor | Descriptor: | AY0 GLU GLU ILE peptide, Tyrosine-protein kinase transforming protein SRC | Authors: | Davidson, J.P, Lubman, O, Rose, T, Waksman, G, Martin, S.F. | Deposit date: | 2001-11-02 | Release date: | 2002-02-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding. J.Am.Chem.Soc., 124, 2002
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2BLP
| RNase before unattenuated X-RAY burn | Descriptor: | CHLORIDE ION, RIBONUCLEASE PANCREATIC PRECURSOR | Authors: | Nanao, M.H, Ravelli, R.B. | Deposit date: | 2005-03-08 | Release date: | 2005-09-07 | Last modified: | 2018-06-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Improving radiation-damage substructures for RIP. Acta Crystallogr. D Biol. Crystallogr., 61, 2005
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2BLX
| HEWL before a high dose x-ray "burn" | Descriptor: | LYSOZYME C, TETRAETHYLENE GLYCOL | Authors: | Nanao, M.H, Ravelli, R.B. | Deposit date: | 2005-03-08 | Release date: | 2005-09-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
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1IWU
| Crystal Structure Analysis of Human lysozyme at 127K. | Descriptor: | CHLORIDE ION, LYSOZYME C | Authors: | Joti, Y, Nakasako, M, Kidera, A, Go, N. | Deposit date: | 2002-06-03 | Release date: | 2002-09-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Nonlinear temperature dependence of the crystal structure of lysozyme: correlation between coordinate shifts and thermal factors. Acta Crystallogr.,Sect.D, 58, 2002
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2XEZ
| Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | Descriptor: | 1,2-ETHANEDIOL, 6-(1H-PYRAZOL-3-YL)-3-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINE, SERINE/THREONINE-PROTEIN KINASE CHK1 | Authors: | Matthews, T.P, McHardy, T, Klair, S, Boxall, K, Fisher, M, Cherry, M, Allen, C.E, Addison, G.J, Ellard, J, Aherne, G.W, Westwood, I.M, vanMontfort, R, Garrett, M.D, Reader, J.C, Collins, I. | Deposit date: | 2010-05-19 | Release date: | 2010-07-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Design and Evaluation of 3,6-Di(Hetero)Aryl Imidazo[1,2-A]Pyrazines as Inhibitors of Checkpoint and Other Kinases. Bioorg.Med.Chem.Lett., 20, 2010
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2C2C
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1SGC
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1IVC
| STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID, CALCIUM ION, ... | Authors: | Jedrzejas, M.J, Luo, M. | Deposit date: | 1994-12-12 | Release date: | 1995-03-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry, 34, 1995
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1IWX
| Crystal Structure Analysis of Human lysozyme at 161K. | Descriptor: | CHLORIDE ION, LYSOZYME C | Authors: | Joti, Y, Nakasako, M, Kidera, A, Go, N. | Deposit date: | 2002-06-03 | Release date: | 2002-09-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Nonlinear temperature dependence of the crystal structure of lysozyme: correlation between coordinate shifts and thermal factors. Acta Crystallogr.,Sect.D, 58, 2002
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1X3D
| Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a | Descriptor: | Fibronectin type-III domain containing protein 3a | Authors: | Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-02 | Release date: | 2005-11-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a To be Published
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1X4G
| Solution structure of RRM domain in Nucleolysin TIAR | Descriptor: | Nucleolysin TIAR | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-14 | Release date: | 2005-11-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of RRM domain in Nucleolysin TIAR To be Published
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