PDB: 36840 resultsInfo pagesStatus searchChemie searchBIRD

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2YCR	Crystal structure of checkpoint kinase 2 in complex with inhibitor PV976 Descriptor: 1,3-BIS{4-[(1E)-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)ETHANEHYDRAZONOYL]PHENYL}UREA, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 Authors: Lountos, G.T, Jobson, A.G, Tropea, J.E, Self, C.R, Pommier, Y, Shoemaker, R.H, Zhang, G, Waugh, D.S. Deposit date: 2011-03-16 Release date: 2011-11-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy. J.Struct.Biol., 176, 2011
5P68	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 269 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.25 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P1O	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 107 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.515 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P6N	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 284 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.109 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P72	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 299 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.049 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P1Y	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 117 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.518 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P7F	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 312 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.079 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1WSE	Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ Descriptor: MANGANESE (II) ION, Ribonuclease HI Authors: Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. Deposit date: 2004-11-05 Release date: 2005-02-08 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345, 2005
5P2C	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 130 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.749 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P7Y	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 331 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.654 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1WFO	The eighth FN3 domain of human sidekick-2 Descriptor: sidekick 2 Authors: Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-05-26 Release date: 2005-06-07 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: The eighth FN3 domain of human sidekick-2 TO BE PUBLISHED
5P8E	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 347 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.219 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P2Q	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 143 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.35 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1HPT	THREE-DIMENSIONAL STRUCTURE OF A RECOMBINANT VARIANT OF HUMAN PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) Descriptor: PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) VARIANT 3 Authors: Hecht, H.J, Szardenings, M, Collins, J, Schomburg, D. Deposit date: 1992-03-27 Release date: 1993-10-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type). J.Mol.Biol., 225, 1992
5P34	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 157 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.209 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P8T	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 362 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.03 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P3I	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 171 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.25 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P3Z	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 188 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.196 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
2CPP	HIGH-RESOLUTION CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM Descriptor: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1987-04-06 Release date: 1987-07-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.63 Å) Cite: High-resolution crystal structure of cytochrome P450cam. J.Mol.Biol., 195, 1987
5P4E	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 203 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.399 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
3FPM	Crystal Structure of a Squarate Inhibitor bound to MAPKAP Kinase-2 Descriptor: 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione, MAP kinase-activated protein kinase 2 Authors: Parris, K.D. Deposit date: 2009-01-05 Release date: 2009-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2) Bioorg.Med.Chem., 17, 2009
1S81	PORCINE TRYPSIN WITH NO INHIBITOR BOUND Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... Authors: Transue, T.R, Krahn, J.M, Gabel, S.A, DeRose, E.F, London, R.E. Deposit date: 2004-01-30 Release date: 2004-03-16 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-ray and NMR characterization of covalent complexes of trypsin, borate, and alcohols. Biochemistry, 43, 2004
5P4W	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 221 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.15 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P5C	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 237 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.339 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P5R	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 252 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.308 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016

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