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1N6P
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Crystal Structure of Human Rab5a A30E mutant complex with GppNHp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-5A
Authors:Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C.
Deposit date:2002-11-11
Release date:2002-11-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
1N6R
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Crystal Structure of Human Rab5a A30L mutant complex with GppNHp
Descriptor: BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C.
Deposit date:2002-11-11
Release date:2002-11-27
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
1NF3
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Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Descriptor: G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ...
Authors:Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R.
Deposit date:2002-12-12
Release date:2003-03-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Embo J., 22, 2003
1NVU
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Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1NVV
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Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1NVW
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Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1NVX
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Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1OIV
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X-ray structure of the small G protein Rab11a in complex with GDP
Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, RAS-RELATED PROTEIN RAB-11A, ...
Authors:Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J.
Deposit date:2003-06-26
Release date:2004-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes
J.Biol.Chem., 279, 2004
1OIW
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X-ray structure of the small G protein Rab11a in complex with GTPgammaS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, RAS-RELATED PROTEIN RAB-11A
Authors:Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J.
Deposit date:2003-06-26
Release date:2004-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes
J.Biol.Chem., 279, 2004
1OIX
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X-ray structure of the small G protein Rab11a in complex with GDP and Pi
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J.
Deposit date:2003-06-26
Release date:2005-01-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic Evidence for Substrate-Assisted GTP Hydrolysis by a Small GTP Binding Protein
Structure, 13, 2005
1OW3
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Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-GTPase-activating protein 1, ...
Authors:Graham, D.L, Lowe, P.N, Grime, G.W, Marsh, M, Rittinger, K, Smerdon, S.J, Gamblin, S.J, Eccleston, J.F.
Deposit date:2003-03-28
Release date:2003-05-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer
Chem.Biol., 9, 2002
1P2S
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H-Ras 166 in 50% 2,2,2 triflouroethanol
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRIFLUOROETHANOL, ...
Authors:Buhrman, G.K, de Serrano, V, Mattos, C.
Deposit date:2003-04-16
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Organic Solvents Order the Dynamic Switch II in Ras Crystals
Structure, 11, 2003
1P2T
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BU of 1p2t by Molmil
H-Ras 166 in Aqueous mother liqour, RT
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Transforming protein p21/H-RAS-1
Authors:Buhrman, G.K, de Serrano, V, Mattos, C.
Deposit date:2003-04-16
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Organic solvents order the dynamic switch II in Ras crystals
Structure, 11, 2003
1P2U
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H-Ras in 50% isopropanol
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Buhrman, G.K, de Serrano, V, Mattos, C.
Deposit date:2003-04-16
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Organic solvents order the dynamic switch II in Ras crystals
Structure, 11, 2003
1P2V
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H-RAS 166 in 60 % 1,6 hexanediol
Descriptor: HEXANE-1,6-DIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Buhrman, G.K, de Serrano, V, Mattos, C.
Deposit date:2003-04-16
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Organic solvents order the dynamic switch II in Ras crystals
Structure, 11, 2003
1PLJ
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CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE 5'-TRIPHOSPHATE P3-[1-(2-NITROPHENYL)ETHYL ESTER], MAGNESIUM ION
Authors:Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S.
Deposit date:1994-03-13
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.
Acta Crystallogr.,Sect.D, 50, 1994
1PLK
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BU of 1plk by Molmil
CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S.
Deposit date:1994-03-13
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.
Acta Crystallogr.,Sect.D, 50, 1994
1PLL
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BU of 1pll by Molmil
CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE
Authors:Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S.
Deposit date:1994-03-13
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.
Acta Crystallogr.,Sect.D, 50, 1994
1Q21
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BU of 1q21 by Molmil
CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
Descriptor: C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Kim, S.-H.
Deposit date:1991-09-25
Release date:1992-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
J.Mol.Biol., 217, 1991
1QBK
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STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX
Descriptor: KARYOPHERIN BETA2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Chook, Y.M, Blobel, G.
Deposit date:1999-04-23
Release date:1999-06-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.
Nature, 399, 1999
1QG2
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CANINE GDP-RAN R76E MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1QG4
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CANINE GDP-RAN F72Y MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1QRA
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STRUCTURE OF P21RAS IN COMPLEX WITH GTP AT 100 K
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1
Authors:Scheidig, A, Burmester, C, Goody, R.S.
Deposit date:1999-06-12
Release date:1999-11-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins.
Structure Fold.Des., 7, 1999
1R2Q
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Crystal Structure of Human Rab5a GTPase Domain at 1.05 A resolution
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Terzyan, S, Zhu, G, Li, G, Zhang, X.C.
Deposit date:2003-09-29
Release date:2003-12-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1RRP
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STRUCTURE OF THE RAN-GPPNHP-RANBD1 COMPLEX
Descriptor: MAGNESIUM ION, NUCLEAR PORE COMPLEX PROTEIN NUP358, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Vetter, I.R, Nowak, C, Nishimoto, T, Kuhlmann, J, Wittinghofer, A.
Deposit date:1999-01-15
Release date:1999-05-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport.
Nature, 398, 1999

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數據於2024-06-12公開中

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