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4ZW3
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BU of 4zw3 by Molmil
X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9b
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2015-05-19
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
4ZX4
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BU of 4zx4 by Molmil
X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10o
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2015-05-20
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
6NYM
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BU of 6nym by Molmil
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2d (OA-2d)
Descriptor: Vacuolating cytotoxin autotransporter
Authors:Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W.
Deposit date:2019-02-11
Release date:2019-03-27
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NYJ
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BU of 6nyj by Molmil
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2b (OA-2b)
Descriptor: Vacuolating cytotoxin autotransporter
Authors:Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W.
Deposit date:2019-02-11
Release date:2019-03-27
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
2KDX
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BU of 2kdx by Molmil
Solution structure of HypA protein
Descriptor: Hydrogenase/urease nickel incorporation protein hypA, ZINC ION
Authors:Xia, W, Li, H, Sze, K.-H.
Deposit date:2009-01-20
Release date:2009-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a nickel chaperone, HypA, from Helicobacter pylori reveals two distinct metal binding sites
J.Am.Chem.Soc., 131, 2009
4ZW7
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BU of 4zw7 by Molmil
X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9m
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2015-05-19
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
4ZW8
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BU of 4zw8 by Molmil
X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9r
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2015-05-19
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
5Y1T
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BU of 5y1t by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,3-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide
Descriptor: (2S)-2-[(2,3-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization
Chin.Chem.Lett., 33, 2022
6NYL
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BU of 6nyl by Molmil
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2c (OA-2c)
Descriptor: Vacuolating cytotoxin autotransporter
Authors:Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W.
Deposit date:2019-02-11
Release date:2019-03-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NYN
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BU of 6nyn by Molmil
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2e (OA-2e)
Descriptor: Vacuolating cytotoxin autotransporter
Authors:Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W.
Deposit date:2019-02-11
Release date:2019-03-27
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5Y1R
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BU of 5y1r by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-( o-tolyl)ureido)pentanamide
Descriptor: (2R)-4-methyl-2-[(2-methylphenyl)carbamoylamino]-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-( o-tolyl)ureido)pentanamide
To Be Published
2JX2
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BU of 2jx2 by Molmil
Solution conformation of RNA-bound NELF-E RRM
Descriptor: Negative elongation factor E
Authors:Jampani, N, Schweimer, K, Wenzel, S, Woehrl, B.M, Roesch, P.
Deposit date:2007-11-02
Release date:2008-04-08
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:NELF-E RRM Undergoes Major Structural Changes in Flexible Protein Regions on Target RNA Binding
Biochemistry, 47, 2008
2K4J
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BU of 2k4j by Molmil
ArsR DNA Binding Domain
Descriptor: Putative TRANSCRIPTIONAL REGULATOR
Authors:Gupta, S.S, Cover, T.L, Krezel, A.M.
Deposit date:2008-06-11
Release date:2008-12-30
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:ArsR DNA Binding Domain
To be Published
1XGO
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BU of 1xgo by Molmil
METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS
Descriptor: METHIONINE AMINOPEPTIDASE
Authors:Tahirov, T.H, Tsukihara, T.
Deposit date:1997-11-18
Release date:1998-02-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus.
J.Mol.Biol., 284, 1998
1XGN
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BU of 1xgn by Molmil
METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS
Descriptor: COBALT (II) ION, METHIONINE AMINOPEPTIDASE
Authors:Tahirov, T.H, Tsukihara, T.
Deposit date:1997-11-17
Release date:1998-02-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus.
J.Mol.Biol., 284, 1998
1XGS
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BU of 1xgs by Molmil
METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS
Descriptor: COBALT (II) ION, METHIONINE AMINOPEPTIDASE
Authors:Tahirov, T.H, Tsukihara, T.
Deposit date:1997-04-25
Release date:1997-07-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus.
J.Mol.Biol., 284, 1998
1XGM
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BU of 1xgm by Molmil
METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS
Descriptor: COBALT (II) ION, METHIONINE AMINOPEPTIDASE
Authors:Tahirov, T.H, Tsukihara, T.
Deposit date:1997-11-17
Release date:1998-02-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus.
J.Mol.Biol., 284, 1998
1Y1N
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BU of 1y1n by Molmil
Identification of SH3 motif in M. Tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Descriptor: Methionine aminopeptidase 1B, POTASSIUM ION
Authors:Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
Deposit date:2004-11-18
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
Biochemistry, 44, 2005
6ATK
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BU of 6atk by Molmil
Crystal structure of the human coronavirus 229E spike protein receptor binding domain in complex with human aminopeptidase N
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
Authors:Wong, A.H, Rini, J.M.
Deposit date:2017-08-29
Release date:2017-12-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.505 Å)
Cite:Receptor-binding loops in alphacoronavirus adaptation and evolution.
Nat Commun, 8, 2017
1XNZ
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BU of 1xnz by Molmil
Crystal Structure of Mn(II) form of E. coli. Methionine Aminopeptidase in complex with 5-(2-chlorophenyl)furan-2-carboxylic acid
Descriptor: 5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ...
Authors:Ye, Q.-Z, Xie, S.-X, Huang, M, Huang, W.-J, Lu, J.-P, Ma, Z.-Q.
Deposit date:2004-10-05
Release date:2004-11-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Metalloform-Selective Inhibitors of Escherichia coli Methionine Aminopeptidase and X-ray Structure of a Mn(II)-Form Enzyme Complexed with an Inhibitor.
J.Am.Chem.Soc., 126, 2004
1Y54
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BU of 1y54 by Molmil
Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed with BRL42715
Descriptor: (7R)-6-FORMYL-7-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC ACID, Beta-lactamase
Authors:Michaux, C, Charlier, P, Frere, J.-M, Wouters, J.
Deposit date:2004-12-02
Release date:2005-03-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene)penem, in Complex with Enterobactercloacae 908R beta-Lactamase: Evidence for a Stereoselective Mechanism from Docking Studies
J.Am.Chem.Soc., 127, 2005
1YJ3
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BU of 1yj3 by Molmil
Crystal structure analysis of product bound methionine aminopeptidase Type 1c from Mycobacterium Tuberculosis
Descriptor: BETA-MERCAPTOETHANOL, COBALT (II) ION, METHIONINE, ...
Authors:Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
Deposit date:2005-01-13
Release date:2005-07-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
Biochemistry, 44, 2005
1YW8
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BU of 1yw8 by Molmil
h-MetAP2 complexed with A751277
Descriptor: 2-[(PHENYLSULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
Authors:Park, C.H.
Deposit date:2005-02-17
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J.Med.Chem., 49, 2006
1YW9
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BU of 1yw9 by Molmil
h-MetAP2 complexed with A849519
Descriptor: 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
Authors:Park, C.H.
Deposit date:2005-02-17
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J.Med.Chem., 49, 2006
3B2P
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BU of 3b2p by Molmil
Crystal structure of E. coli Aminopeptidase N in complex with arginine
Descriptor: ARGININE, Aminopeptidase N, GLYCEROL, ...
Authors:Anthony, A, Leslie, G, Matthews, B.W.
Deposit date:2007-10-18
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the unusual specificity of Escherichia coli aminopeptidase N.
Biochemistry, 47, 2008

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數據於2024-11-06公開中

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