PDB: 2861 resultsInfo pagesStatus searchChemie searchBIRD

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7L20	Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt. Descriptor: 16S rRNA mitochondrial, 39 S P-site finger, 39S ribosomal protein L10, ... Authors: Agrawal, E, Koripella, R. Deposit date: 2020-12-15 Release date: 2021-05-12 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance. Nat Commun, 12, 2021
4L3C	Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... Authors: Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. Deposit date: 2013-06-05 Release date: 2013-12-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin. J.Biol.Chem., 289, 2014
5HD1	Crystal structure of antimicrobial peptide Pyrrhocoricin bound to the Thermus thermophilus 70S ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. Deposit date: 2016-01-04 Release date: 2016-04-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
5HCP	Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. Deposit date: 2016-01-04 Release date: 2016-04-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.894 Å) Cite: Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
4D65	Structure of porin Omp-Pst2 from P. stuartii; the asymmetric unit contains a dimer of trimers. Descriptor: 3-HYDROXY-TETRADECANOIC ACID, LAURYL DIMETHYLAMINE-N-OXIDE, MYRISTIC ACID, ... Authors: Nasrallah, C, Colletier, J.P. Deposit date: 2014-11-08 Release date: 2016-03-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Porin self-association enables cell-to-cell contact inProvidencia stuartiifloating communities. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4L71	Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Maehigashi, T, Dunkle, J.A, Dunham, C.M. Deposit date: 2013-06-13 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.900001 Å) Cite: Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
4LF7	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus Descriptor: 16S rRNA, MAGNESIUM ION, PAROMOMYCIN, ... Authors: Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T. Deposit date: 2013-06-26 Release date: 2014-07-02 Method: X-RAY DIFFRACTION (3.1484 Å) Cite: Crystal Structure of 30S ribosomal subunit from Thermus thermophilus To be Published, 2013
5IB8	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. Deposit date: 2016-02-22 Release date: 2016-05-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.13 Å) Cite: The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
5IBB	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. Deposit date: 2016-02-22 Release date: 2016-05-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.96 Å) Cite: The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
5J88	Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... Authors: Cocozaki, A, Ferguson, A. Deposit date: 2016-04-07 Release date: 2016-07-06 Last modified: 2016-12-07 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
5IWA	Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic Descriptor: (2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acid, 16S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Chieko, N, Masahito, K, Takemoto, C, Yokoyama, S, Connell, S.R, Fucini, P. Deposit date: 2016-03-22 Release date: 2016-04-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proc.Natl.Acad.Sci.USA, 113, 2016
4LFA	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus Descriptor: 16S rRNA, HYGROMYCIN B, MAGNESIUM ION, ... Authors: Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T. Deposit date: 2013-06-26 Release date: 2014-07-02 Method: X-RAY DIFFRACTION (3.6461 Å) Cite: Crystal Structure of 30S ribosomal subunit from Thermus thermophilus to be published, 2013
4K3N	Phosphonic Arginine Mimetics as Inhibitors of the M17 Aminopeptidases from Plasmodium falciparum Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ... Authors: McGowan, S. Deposit date: 2013-04-11 Release date: 2013-06-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum. J.Med.Chem., 56, 2013
1N32	Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position at the a site with paromomycin Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V. Deposit date: 2002-10-25 Release date: 2002-11-29 Last modified: 2019-11-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form Cell(Cambridge,Mass.), 111, 2002
7KG2	Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site and L-histidine bound at the allosteric site Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... Authors: Saran, S, Majdi Yazdi, M, Sanders, D.A.R. Deposit date: 2020-10-15 Release date: 2021-10-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Reversing the roles of a crucial hydrogen-bonding pair: a lysine-insensitive mutant of Campylobacter jejuni dihydrodipicolinate synthase, H59K, binds histidine in its allosteric site To be Published
7KH4	Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... Authors: Saran, S, Majdi Yazdi, M, Sanders, D.A.R. Deposit date: 2020-10-19 Release date: 2021-10-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni To Be Published
5IQR	Structure of RelA bound to the 70S ribosome Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... Authors: Brown, A, Fernandez, I.S, Gordiyenko, Y, Ramakrishnan, V. Deposit date: 2016-03-11 Release date: 2016-05-04 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Ribosome-dependent activation of stringent control. Nature, 534, 2016
5J30	Thermus thermophilus 70S termination complex containing E. coli RF1 Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Hoffer, E.D, Dunham, C.M. Deposit date: 2016-03-30 Release date: 2016-10-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
5J4C	Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. Deposit date: 2016-03-31 Release date: 2016-04-27 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
7KPC	Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88Q mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... Authors: Saran, S, Sanders, D.A.R. Deposit date: 2020-11-10 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.76 Å) Cite: THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND. To Be Published
4L47	Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U on the Ribosome Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Maehigashi, T, Dunkle, J.A, Dunham, C.M. Deposit date: 2013-06-07 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.220001 Å) Cite: Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
5J8B	Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Gagnon, M.G, Lin, J, Steitz, T.A. Deposit date: 2016-04-07 Release date: 2016-05-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Elongation factor 4 remodels the A-site tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016
4LFZ	Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U in the Absence of Paromomycin Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Maehigashi, T, Dunkle, J.A, Dunham, C.M. Deposit date: 2013-06-27 Release date: 2014-08-06 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (3.92000055 Å) Cite: Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
5J3C	Thermus thermophilus 70S termination complex containing E. coli RF1 Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Hoffer, E.D, Dunham, C.M. Deposit date: 2016-03-30 Release date: 2016-10-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
4KT0	Crystal structure of a virus like photosystem I from the cyanobacterium Synechocystis PCC 6803 Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... Authors: Mazor, Y, Nataf, D, Toporik, H, Nelson, N. Deposit date: 2013-05-19 Release date: 2014-02-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of virus-like photosystem I complexes from the mesophilic cyanobacterium Synechocystis PCC 6803. Elife, 3, 2014

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