5XP7
| C-Src in complex with ATP-CHCl | Descriptor: | GLYCEROL, MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, ... | Authors: | Guo, M, Dai, S, Duan, Y, Chen, L, Chen, Y. | Deposit date: | 2017-06-01 | Release date: | 2017-09-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.012 Å) | Cite: | Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases. J. Am. Chem. Soc., 139, 2017
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5MM9
| VIM-2_2b. Metallo-beta-Lactamase Inhibitors by Bioisosteric Replacement: Preparation, Activity and Binding | Descriptor: | (2~{R})-2-diethoxyphosphoryl-5-phenyl-pentane-1-thiol, MAGNESIUM ION, Metallo-beta-lactamase VIM-17, ... | Authors: | Skagseth, S, Akhter, S, Paulsen, M.H, Samuelsen, O, Muhammad, Z, Leiros, H.-K.S, Bayer, A. | Deposit date: | 2016-12-08 | Release date: | 2017-03-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Metallo-beta-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding. Eur J Med Chem, 135, 2017
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4YZD
| Crystal Structure of human phosphorylated IRE1alpha in complex with ADP-Mg | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1 | Authors: | Concha, N.O. | Deposit date: | 2015-03-24 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity. Mol.Pharmacol., 88, 2015
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1RNB
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8Z10
| Human beta-catenin crystal structure | Descriptor: | Catenin beta-1, PROLINE | Authors: | Tim, F. | Deposit date: | 2024-04-10 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of Beta-catenin To Be Published
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1G2X
| Sequence induced trimerization of krait PLA2: crystal structure of the trimeric form of krait PLA2 | Descriptor: | PHOSPHOLIPASE A2 | Authors: | Singh, G, Gourinath, S, Sharma, S, Bhanumathi, S, Paramsivam, M, Singh, T.P. | Deposit date: | 2000-10-22 | Release date: | 2003-06-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution. Acta Crystallogr.,Sect.F, 61, 2005
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1BRJ
| BARNASE MUTANT WITH ILE 88 REPLACED BY ALA | Descriptor: | BARNASE, ZINC ION | Authors: | Cramer, P.C, Buckle, A, Fersht, A. | Deposit date: | 1995-03-09 | Release date: | 1995-07-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities. Biochemistry, 35, 1996
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1BRH
| BARNASE MUTANT WITH LEU 14 REPLACED BY ALA | Descriptor: | BARNASE, ZINC ION | Authors: | Cramer, P.C, Buckle, A, Fersht, A. | Deposit date: | 1995-03-09 | Release date: | 1995-07-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities. Biochemistry, 35, 1996
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6ALW
| The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with 12-Methyl Myristic Acid (C15:0) to 1.63 Angstrom resolution | Descriptor: | (12R)-12-methyltetradecanoic acid, (12S)-12-methyltetradecanoic acid, EDD domain protein, ... | Authors: | Cuypers, M.G, Ericson, M, Subramanian, C, White, S.W, Rock, C.O. | Deposit date: | 2017-08-08 | Release date: | 2018-11-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Acyl-chain selectivity and physiological roles ofStaphylococcus aureusfatty acid-binding proteins. J. Biol. Chem., 294, 2019
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1MB3
| CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR DIVK AT PH 8.5 IN COMPLEX WITH MG2+ | Descriptor: | MAGNESIUM ION, cell division response regulator DivK | Authors: | Guillet, V, Ohta, N, Cabantous, S, Newton, A, Samama, J.-P, Structural Proteomics in Europe (SPINE) | Deposit date: | 2002-08-02 | Release date: | 2002-12-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Crystallographic and Biochemical Studies of DivK Reveal Novel Features of
an Essential Response Regulator in Caulobacter crescentus. J.Biol.Chem., 277, 2002
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3GFQ
| Structure of YhdA, K109L variant | Descriptor: | FLAVIN MONONUCLEOTIDE, FMN-dependent NADPH-azoreductase | Authors: | Staunig, N, Gruber, K. | Deposit date: | 2009-02-27 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.996 Å) | Cite: | A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase Febs J., 276, 2009
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5A2Q
| Structure of the HCV IRES bound to the human ribosome | Descriptor: | 18S RRNA, HCV IRES, MAGNESIUM ION, ... | Authors: | Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. | Deposit date: | 2015-05-21 | Release date: | 2015-07-15 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
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4ARC
| Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucine in the editing conformation | Descriptor: | LEUCINE, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | Deposit date: | 2012-04-23 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
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1CJC
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5LQF
| CDK1/CyclinB1/CKS2 in complex with NU6102 | Descriptor: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, G2/mitotic-specific cyclin-B1, ... | Authors: | Coxon, C.R, Anscombe, E, Harnor, S.J, Martin, M.P, Carbain, B.J, Hardcastle, I.R, Harlow, L.K, Korolchuk, S, Matheson, C.J, Noble, M.E, Newell, D.R, Turner, D.M, Sivaprakasam, M, Wang, L.Z, Wong, C, Golding, B.T, Griffin, R.J, Endicott, J.A, Cano, C. | Deposit date: | 2016-08-17 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J. Med. Chem., 60, 2017
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3GFS
| Structure of YhdA, K109D/D137K variant | Descriptor: | FLAVIN MONONUCLEOTIDE, FMN-dependent NADPH-azoreductase | Authors: | Staunig, N, Gruber, K. | Deposit date: | 2009-02-27 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase Febs J., 276, 2009
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1XMZ
| Crystal structure of the dark state of kindling fluorescent protein kfp from anemonia sulcata | Descriptor: | BETA-MERCAPTOETHANOL, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Quillin, M.L, Anstrom, D.M, Shu, X, O'Leary, S, Kallio, K, Chudakov, D.M, Remington, S.J. | Deposit date: | 2004-10-04 | Release date: | 2005-04-19 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Kindling Fluorescent Protein from Anemonia sulcata: Dark-State Structure at 1.38 Resolution Biochemistry, 44, 2005
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1SIB
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2YJF
| Oligomeric assembly of actin bound to MRTF-A | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R. | Deposit date: | 2011-05-19 | Release date: | 2011-07-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator. Sci Signal, 4, 2011
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1UK6
| Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with propionate | Descriptor: | 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, PROPANOIC ACID | Authors: | Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. | Deposit date: | 2003-08-19 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
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1UK8
| Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with n-valerate | Descriptor: | 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, PENTANOIC ACID | Authors: | Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. | Deposit date: | 2003-08-19 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
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5LJO
| E. coli BAM complex (BamABCDE) by cryoEM | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Schffrin, B, Calabrese, A.N, Ashcroft, A.E, Brockwell, D.J. | Deposit date: | 2016-07-19 | Release date: | 2016-10-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Lateral opening in the intact beta-barrel assembly machinery captured by cryo-EM. Nat Commun, 7, 2016
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1UK7
| Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with n-butyrate | Descriptor: | 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, butanoic acid | Authors: | Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. | Deposit date: | 2003-08-19 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
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1UKA
| Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with (S)-2-methylbutyrate | Descriptor: | 2-METHYLBUTANOIC ACID, 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase | Authors: | Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. | Deposit date: | 2003-08-19 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
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1UKB
| Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with benzoate | Descriptor: | 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, BENZOIC ACID | Authors: | Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. | Deposit date: | 2003-08-19 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
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