6YOV
 
 | | OCT4-SOX2-bound nucleosome - SHL+6 | | Descriptor: | DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... | | Authors: | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | | Deposit date: | 2020-04-15 | | Release date: | 2020-05-06 | | Last modified: | 2020-07-08 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
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7E8I
 | | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin | | Descriptor: | BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ... | | Authors: | Dai, Y, Dai, L, Zhou, Z. | | Deposit date: | 2021-03-01 | | Release date: | 2021-06-30 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Mol.Cell, 81, 2021
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7ZI4
 | | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B. | | Deposit date: | 2022-04-07 | | Release date: | 2023-04-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
To Be Published
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8AV6
 | | CryoEM structure of INO80 core nucleosome complex in closed grappler conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DASH complex subunit DAD4, ... | | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | Deposit date: | 2022-08-26 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (4.68 Å) | | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8BVW
 | | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | | Deposit date: | 2022-12-20 | | Release date: | 2023-05-03 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
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7EGP
 | | The structure of SWI/SNF-nucleosome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ... | | Authors: | Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. | | Deposit date: | 2021-03-24 | | Release date: | 2022-01-12 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity.
Cell Discov, 7, 2021
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6GEN
 | | Chromatin remodeller-nucleosome complex at 4.5 A resolution. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | | Deposit date: | 2018-04-27 | | Release date: | 2018-10-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
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6GEJ
 | | Chromatin remodeller-nucleosome complex at 3.6 A resolution. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | | Deposit date: | 2018-04-26 | | Release date: | 2018-10-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
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6FML
 | | CryoEM Structure INO80core Nucleosome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin related protein 5, ... | | Authors: | Eustermann, S, Schall, K, Kostrewa, D, Strauss, M, Hopfner, K. | | Deposit date: | 2018-01-31 | | Release date: | 2018-04-25 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.34 Å) | | Cite: | Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.
Nature, 556, 2018
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6KW5
 | | The ClassC RSC-Nucleosome Complex | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | Deposit date: | 2019-09-06 | | Release date: | 2020-09-09 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (10.13 Å) | | Cite: | Structure of the RSC complex bound to the nucleosome
To Be Published
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6KW4
 | | The ClassB RSC-Nucleosome Complex | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | Deposit date: | 2019-09-06 | | Release date: | 2019-11-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (7.55 Å) | | Cite: | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
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6LTJ
 | | Structure of nucleosome-bound human BAF complex | | Descriptor: | AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... | | Authors: | He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. | | Deposit date: | 2020-01-22 | | Release date: | 2020-02-12 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
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8F1E
 | | Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) and H2A-H2B | | Descriptor: | GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Histone H2A.2, ... | | Authors: | Jiou, J, Chook, Y.M. | | Deposit date: | 2022-11-04 | | Release date: | 2023-07-26 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6T90
 | | OCT4-SOX2-bound nucleosome - SHL-6 | | Descriptor: | DNA (146-MER), Green fluorescent protein,POU domain, class 5, ... | | Authors: | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | | Deposit date: | 2019-10-25 | | Release date: | 2020-05-06 | | Last modified: | 2020-07-08 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
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6TDA
 | | Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC58, ... | | Authors: | Wagner, F.R, Dienemann, C, Wang, H, Stuetzer, A, Tegunov, D, Urlaub, H, Cramer, P. | | Deposit date: | 2019-11-08 | | Release date: | 2020-03-18 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (15 Å) | | Cite: | Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome.
Nature, 579, 2020
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6UXW
 | | SWI/SNF nucleosome complex with ADP-BeFx | | Descriptor: | 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | He, Y, Han, Y. | | Deposit date: | 2019-11-08 | | Release date: | 2020-03-18 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (8.96 Å) | | Cite: | Cryo-EM structure of SWI/SNF complex bound to a nucleosome.
Nature, 579, 2020
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6V92
 | | RSC-NCP | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC14, ... | | Authors: | Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E. | | Deposit date: | 2019-12-13 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
Elife, 8, 2019
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6VZ4
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7JZV
 | | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | | Descriptor: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | | Authors: | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | | Deposit date: | 2020-09-02 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
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7TAN
 | | Structure of VRK1 C-terminal tail bound to nucleosome core particle | | Descriptor: | Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, Histone H3.2, ... | | Authors: | Spangler, C.J, Budziszewski, G.R, McGinty, R.K. | | Deposit date: | 2021-12-21 | | Release date: | 2022-05-04 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.
Nucleic Acids Res., 50, 2022
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7SSA
 | | Cryo-EM structure of pioneer factor Cbf1 bound to the nucleosome | | Descriptor: | Centromere-binding protein 1, DNA (137-MER), Histone H2A.1, ... | | Authors: | Eek, P, Tan, S. | | Deposit date: | 2021-11-10 | | Release date: | 2023-04-05 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions.
Mol.Cell, 83, 2023
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7U0G
 | | structure of LIN28b nucleosome bound 3 OCT4 | | Descriptor: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | Authors: | Lian, T, Guan, R, Bai, Y. | | Deposit date: | 2022-02-18 | | Release date: | 2023-06-28 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7U0I
 | | Structure of LIN28b nucleosome bound 2 OCT4 | | Descriptor: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | Authors: | Tengfei, L, Guan, R, Bai, Y. | | Deposit date: | 2022-02-18 | | Release date: | 2023-06-28 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7TRF
 | | Human telomerase catalytic core RNP with H2A/H2B | | Descriptor: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | | Deposit date: | 2022-01-28 | | Release date: | 2022-04-20 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
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7LYB
 | | Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c | | Descriptor: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | Deposit date: | 2021-03-06 | | Release date: | 2021-07-28 | | Last modified: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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