6LSE
| Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form) | Descriptor: | Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ... | Authors: | Wang, M, Shu, B, Jing, X, Gong, P. | Deposit date: | 2020-01-17 | Release date: | 2020-04-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
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5Y3D
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1HHS
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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5ZIU
| Crystal structure of human Entervirus D68 RdRp | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, RdRp | Authors: | Wang, M.L, Zhang, Y, Chen, Y.P, Lu, D.R, Jiang, H, Chen, Y.J, Li, L, Zhang, C.H, Shi, Q.L, Su, D. | Deposit date: | 2018-03-17 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.147 Å) | Cite: | Crystal structure of human Entervirus D68 RdRp in complex with NADPH To Be Published
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1HHT
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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5ZIT
| Crystal structure of human Enterovirus D68 RdRp in complex with NADPH | Descriptor: | DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RdRp | Authors: | Wang, M.L, Li, L, Chen, Y.P, Jiang, H, Zhang, Y, Su, D. | Deposit date: | 2018-03-17 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.196 Å) | Cite: | Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., 2020
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1HI1
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-01 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HI8
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MAGNESIUM ION, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-03 | Release date: | 2001-03-27 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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3KMS
| G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure | Descriptor: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | Deposit date: | 2009-11-11 | Release date: | 2010-07-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
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3KOA
| M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP | Descriptor: | 3D polymerase, DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | Deposit date: | 2009-11-13 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
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3KNA
| M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA | Descriptor: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | Deposit date: | 2009-11-12 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
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3KLV
| M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA | Descriptor: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | Authors: | Ferrer-Orta, C, Sierra, M, Agudo, R, Perez-Luque, R, Arias, A, Verdaguer, N. | Deposit date: | 2009-11-09 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
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3KMQ
| G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, tetragonal structure | Descriptor: | 3D polymerase, RNA (5'-R(*GP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*C)-3') | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | Deposit date: | 2009-11-11 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
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6LSF
| Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form) | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... | Authors: | Wang, M, Shu, B, Jing, X, Gong, P. | Deposit date: | 2020-01-17 | Release date: | 2020-04-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
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6LSG
| Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form) | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... | Authors: | Li, R, Wang, M, Jing, X, Gong, P. | Deposit date: | 2020-01-17 | Release date: | 2020-04-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
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4NLV
| Poliovirus Polymerase - G289A/C290F Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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4NLU
| Poliovirus Polymerase - G289A Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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4NRT
| Human Norovirus polymerase bound to Compound 6 (suramin derivative) | Descriptor: | 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, hNV-RdRp | Authors: | Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Milani, M, Bolognesi, M. | Deposit date: | 2013-11-27 | Release date: | 2014-10-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.022 Å) | Cite: | Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds. Plos One, 9, 2014
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4NLW
| Poliovirus Polymerase - G289A/C290I Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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4NLY
| Poliovirus Polymerase - C290E Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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4NLR
| Poliovirus Polymerase - C290S Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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6LSH
| Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form) | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... | Authors: | Li, R, Wang, M, Jing, X, Gong, P. | Deposit date: | 2020-01-17 | Release date: | 2020-04-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.231 Å) | Cite: | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
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5FJ6
| Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T. | Deposit date: | 2015-10-06 | Release date: | 2015-11-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes. Nat.Commun., 6, 2015
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5F8L
| Enterovirus 71 Polymerase Elongation Complex (C3S1 Form) | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... | Authors: | Shu, B, Gong, P. | Deposit date: | 2015-12-09 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.812 Å) | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8H
| Enterovirus 71 Polymerase Elongation Complex (C1S1/2 Form) | Descriptor: | Genome polyprotein, MAGNESIUM ION, RNA (35-MER), ... | Authors: | Shu, B, Gong, P. | Deposit date: | 2015-12-09 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
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