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1OZS
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BU of 1ozs by Molmil
C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Lindhout, D.A, Sykes, B.D.
Deposit date:2003-04-09
Release date:2003-09-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I.
J.Biol.Chem., 278, 2003
1B99
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BU of 1b99 by Molmil
3'-FLUORO-URIDINE DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor: 2',3'-DIDEOXY-3'-FLUORO-URIDIDINE-5'-DIPHOSPHATE, PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), PYROPHOSPHATE 2-
Authors:Janin, J, Xu, Y.
Deposit date:1999-02-22
Release date:1999-06-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Catalytic mechanism of nucleoside diphosphate kinase investigated using nucleotide analogues, viscosity effects, and X-ray crystallography.
Biochemistry, 38, 1999
3D9V
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BU of 3d9v by Molmil
CRYSTAL STRUCTURE OF ROCK I BOUND TO H-1152P A DI-METHYLATED VARIANT OF FASUDIL
Descriptor: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, Rho-associated protein kinase 1
Authors:Jacobs, M.
Deposit date:2008-05-27
Release date:2008-06-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structure of dimeric ROCK I reveals the mechanism for ligand selectivity.
J.Biol.Chem., 281, 2006
1B4S
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BU of 1b4s by Molmil
STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE H122G MUTANT
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE, ...
Authors:Meyer, P, Janin, J.
Deposit date:1998-12-28
Release date:1999-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleophilic activation by positioning in phosphoryl transfer catalyzed by nucleoside diphosphate kinase.
Biochemistry, 38, 1999
7YK2
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BU of 7yk2 by Molmil
Cryo-EM structure of Apo-alpha-syn fibril
Descriptor: Alpha-synuclein
Authors:Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
Deposit date:2022-07-21
Release date:2023-03-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7YK8
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BU of 7yk8 by Molmil
Cryo-EM structure of dLAG3-alpha-syn fibril
Descriptor: Alpha-synuclein
Authors:Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
Deposit date:2022-07-22
Release date:2023-03-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7K3J
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BU of 7k3j by Molmil
Crystal structure of dLC8 in complex with Panoramix TQT+TQ peptide
Descriptor: Dynein light chain 1, cytoplasmic, Protein panoramix, ...
Authors:Wang, J, Patel, D.J.
Deposit date:2020-09-11
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
7K3K
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BU of 7k3k by Molmil
Crystal structure of dLC8 in complex with Panoramix TQT peptide
Descriptor: Dynein light chain 1, cytoplasmic, Protein panoramix
Authors:Wang, J, Patel, D.J.
Deposit date:2020-09-11
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.415 Å)
Cite:Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
7K3L
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BU of 7k3l by Molmil
Crystal structure of dLC8 in complex with Panoramix TQ peptide
Descriptor: 1,2-ETHANEDIOL, Dynein light chain 1, cytoplasmic, ...
Authors:Wang, J, Patel, D.J.
Deposit date:2020-09-11
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
1CD9
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BU of 1cd9 by Molmil
2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (G-CSF RECEPTOR), PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR)
Authors:Aritomi, M, Kunishima, N, Okamoto, T, Kuroki, R, Ota, Y, Morikawa, K.
Deposit date:1999-03-08
Release date:2000-03-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme.
Nature, 401, 1999
7JT9
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BU of 7jt9 by Molmil
Fgr SH3 domain crystal structure
Descriptor: Tyrosine-protein kinase Fgr
Authors:Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2020-08-17
Release date:2022-01-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr.
J.Mol.Biol., 434, 2022
1E0S
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BU of 1e0s by Molmil
small G protein Arf6-GDP
Descriptor: ADP-ribosylation factor 6, AMMONIUM ION, BETA-MERCAPTOETHANOL, ...
Authors:Menetrey, J, Cherfils, J.
Deposit date:2000-04-06
Release date:2000-04-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of Arf6-Gdp Suggests a Basis for Guanine Nucleotide Exchange Factors Specificity
Nat.Struct.Biol., 7, 2000
5FLC
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BU of 5flc by Molmil
Architecture of human mTOR Complex 1 - 5.9 Angstrom reconstruction
Descriptor: FKBP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, REGULATORY-ASSOCIATED PROTEIN OF MTOR, ...
Authors:Aylett, C.H.S, Sauer, E, Imseng, S, Boehringer, D, Hall, M.N, Ban, N, Maier, T.
Deposit date:2015-10-23
Release date:2015-12-30
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Architecture of Human Mtor Complex 1
Science, 351, 2016
7YNQ
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BU of 7ynq by Molmil
PiB-bound alpha-synuclein fibrils conformation 2
Descriptor: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:PiB-bound alpha-synuclein fibrils conformation 2
To Be Published
7YNT
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BU of 7ynt by Molmil
pFTAA-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:pFTAA-bound alpha-synuclein fibrils
To Be Published
7YNM
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BU of 7ynm by Molmil
ThT-bound alpha-synuclein fibrils conformation 1
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:ThT-bound alpha-synuclein fibrils conformation 1
To Be Published
7YNL
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BU of 7ynl by Molmil
EB-bound alpha-synuclein fibrils
Descriptor: 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:EB-bound alpha-synuclein fibrils
To Be Published
7YNR
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BU of 7ynr by Molmil
C05-03-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:C05-03-bound alpha-synuclein fibrils
To Be Published
7YNP
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BU of 7ynp by Molmil
BF227-bound alpha-synuclein fibrils
Descriptor: 5-[(~{E})-2-(6-methoxy-1,3-benzoxazol-2-yl)ethenyl]-~{N},~{N}-dimethyl-1,3-thiazol-2-amine, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:BF227-bound alpha-synuclein fibrils
To Be Published
7YNN
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BU of 7ynn by Molmil
ThT-bound alpha-synuclein fibrils conformation 2
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:ThT-bound alpha-synuclein fibrils conformation 2
To Be Published
7YNO
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BU of 7yno by Molmil
PiB-bound alpha-synuclein fibrils conformation 1
Descriptor: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:PiB-bound alpha-synuclein fibrils conformation 1
To Be Published
7YNG
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BU of 7yng by Molmil
CR-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-30
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:CR-bound alpha-synuclein fibrils
To Be Published
7YNS
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BU of 7yns by Molmil
SIL5-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SIL5-bound alpha-synuclein fibrils
To Be Published
7YNF
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BU of 7ynf by Molmil
CCA-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-30
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:CCA-bound alpha-synuclein fibrils
To Be Published
8A9L
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BU of 8a9l by Molmil
Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies
Descriptor: Alpha-synuclein, Unknown fragment
Authors:Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M.
Deposit date:2022-06-28
Release date:2022-08-31
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structures of alpha-synuclein filaments from human brains with Lewy pathology.
Nature, 610, 2022

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數據於2024-07-31公開中

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