3WGE
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![BU of 3wge by Molmil](/molmil-images/mine/3wge) | Crystal structure of ERp46 Trx2 | Descriptor: | GLYCEROL, Thioredoxin domain-containing protein 5 | Authors: | Inaba, K, Suzuki, M, Kojima, R. | Deposit date: | 2013-08-04 | Release date: | 2014-06-25 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Radically different thioredoxin domain arrangement of ERp46, an efficient disulfide bond introducer of the mammalian PDI family Structure, 22, 2014
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2VU6
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3RY2
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![BU of 3ry2 by Molmil](/molmil-images/mine/3ry2) | Wild-type core streptavidin-biotin complex at atomic resolution | Descriptor: | BIOTIN, GLYCEROL, Streptavidin | Authors: | Stenkamp, R.E, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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3X35
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![BU of 3x35 by Molmil](/molmil-images/mine/3x35) | Crystal structure of the reduced form of the solubilized domain of porcine cytochrome b5 in form 2 crystal | Descriptor: | ACETATE ION, Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hirano, Y, Kimura, S, Tamada, T. | Deposit date: | 2015-01-14 | Release date: | 2015-07-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | High-resolution crystal structures of the solubilized domain of porcine cytochrome b5. Acta Crystallogr.,Sect.D, 71, 2015
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2NX0
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![BU of 2nx0 by Molmil](/molmil-images/mine/2nx0) | Ferrous nitrosyl blackfin tuna myoglobin | Descriptor: | Myoglobin, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Schreiter, E.R, Rodriguez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J. | Deposit date: | 2006-11-16 | Release date: | 2007-05-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | S-nitrosylation-induced conformational change in blackfin tuna myoglobin. J.Biol.Chem., 282, 2007
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6IIP
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![BU of 6iip by Molmil](/molmil-images/mine/6iip) | Apo-form structure of the HRP3 PWWP domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hepatoma-derived growth factor-related protein 3, SULFATE ION | Authors: | Wang, Z, Tian, W. | Deposit date: | 2018-10-07 | Release date: | 2019-04-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (0.951 Å) | Cite: | Apo-form structure of the HRP3 PWWP domain Nucleic Acids Res., 2019
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5E7W
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![BU of 5e7w by Molmil](/molmil-images/mine/5e7w) | X-ray Structure of Human Recombinant 2Zn insulin at 0.92 Angstrom | Descriptor: | ACETATE ION, Insulin, N-PROPANOL, ... | Authors: | Lisgarten, D.R, Naylor, C.E, Palmer, R.A, Lobley, C.M.C. | Deposit date: | 2015-10-13 | Release date: | 2016-10-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (0.9519 Å) | Cite: | Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K. Chem Cent J, 11, 2017
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5OUK
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![BU of 5ouk by Molmil](/molmil-images/mine/5ouk) | Crystal structure of human AKR1B1 complexed with NADP+ and compound 41 | Descriptor: | 2-[9-fluoranyl-5-(4-methoxyphenyl)-3-methyl-1-oxidanylidene-pyrimido[4,5-c]quinolin-2-yl]ethanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Metwally, K, Podjarny, A. | Deposit date: | 2017-08-24 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (0.959 Å) | Cite: | Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. Eur J Med Chem, 152, 2018
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6I74
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![BU of 6i74 by Molmil](/molmil-images/mine/6i74) | Galectin-3C in complex with substituted polyfluoroaryl monothiogalactoside derivative 1 | Descriptor: | (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,4,5,6-pentakis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, Galectin-3 | Authors: | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | Deposit date: | 2018-11-15 | Release date: | 2019-01-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (0.959 Å) | Cite: | Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects. Org. Biomol. Chem., 17, 2019
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6RKN
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![BU of 6rkn by Molmil](/molmil-images/mine/6rkn) | Human Carbonic Anhydrase II in complex with a fluorinated Benzenesulfonamide. | Descriptor: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-FLUOROBENZENESULFONAMIDE, Carbonic anhydrase 2, ... | Authors: | Gloeckner, S, Heine, A, Klebe, G. | Deposit date: | 2019-04-30 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (0.959 Å) | Cite: | The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
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3KFF
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![BU of 3kff by Molmil](/molmil-images/mine/3kff) | Major mouse urinary protein IV complexed with 2-sec-butyl-4,5-dihydrothiazole | Descriptor: | 2-[(1R)-1-methylpropyl]-4,5-dihydro-1,3-thiazole, 2-[(1S)-1-methylpropyl]-4,5-dihydro-1,3-thiazole, CHLORIDE ION, ... | Authors: | Perez-Miller, S, Zou, Q, Hurley, T.D. | Deposit date: | 2009-10-27 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones. Protein Sci., 19, 2010
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3AGN
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![BU of 3agn by Molmil](/molmil-images/mine/3agn) | Crystal Structure of Ustilago sphaerogena Ribonuclease U2 Complexed with adenosine 3'-monophosphate | Descriptor: | CALCIUM ION, Ribonuclease U2, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Authors: | Noguchi, S. | Deposit date: | 2010-04-03 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Isomerization mechanism of aspartate to isoaspartate implied by structures of Ustilago sphaerogena ribonuclease U2 complexed with adenosine 3'-monophosphate Acta Crystallogr.,Sect.D, 66, 2010
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8B3R
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5MOS
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![BU of 5mos by Molmil](/molmil-images/mine/5mos) | Joint X-ray/neutron structure of cationic trypsin in complex with N-amidinopiperidine | Descriptor: | CALCIUM ION, Cationic trypsin, SULFATE ION, ... | Authors: | Schiebel, J, Schrader, T.E, Ostermann, A, Heine, A, Klebe, G. | Deposit date: | 2016-12-14 | Release date: | 2018-02-28 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (0.96 Å), X-RAY DIFFRACTION | Cite: | Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
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6J60
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![BU of 6j60 by Molmil](/molmil-images/mine/6j60) | hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217) | Descriptor: | 9-mer peptide (GFGGNDNFG) from Heterogeneous nuclear ribonucleoprotein A1 | Authors: | Luo, F, Zhou, H, Gui, X, Li, D, Li, X, Liu, C. | Deposit date: | 2019-01-12 | Release date: | 2019-04-03 | Last modified: | 2024-03-27 | Method: | ELECTRON CRYSTALLOGRAPHY (0.96 Å) | Cite: | Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly. Nat Commun, 10, 2019
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3O5Q
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![BU of 3o5q by Molmil](/molmil-images/mine/3o5q) | Fk1 domain mutant A19T of FKBP51, crystal form IV, in presence of DMSO | Descriptor: | DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Bracher, A, Kozany, C, Thost, A.-K, Hausch, F. | Deposit date: | 2010-07-28 | Release date: | 2011-06-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. Acta Crystallogr.,Sect.D, 67, 2011
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7X4J
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![BU of 7x4j by Molmil](/molmil-images/mine/7x4j) | The 0.96 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with arachidic acid | Descriptor: | Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... | Authors: | Sugiyama, S, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. | Deposit date: | 2022-03-02 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | The 0.96 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with arachidic acid To Be Published
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6JPT
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![BU of 6jpt by Molmil](/molmil-images/mine/6jpt) | Crystal structure of human PAC3 homodimer (trigonal form) | Descriptor: | POTASSIUM ION, Proteasome assembly chaperone 3, THIOCYANATE ION | Authors: | Satoh, T, Yagi-Utsumi, M, Okamoto, K, Kurimoto, E, Tanaka, K, Kato, K. | Deposit date: | 2019-03-27 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Molecular and Structural Basis of the Proteasome alpha Subunit Assembly Mechanism Mediated by the Proteasome-Assembling Chaperone PAC3-PAC4 Heterodimer. Int J Mol Sci, 20, 2019
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1U2H
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![BU of 1u2h by Molmil](/molmil-images/mine/1u2h) | X-ray Structure of the N-terminally truncated human APEP-1 | Descriptor: | Aortic preferentially expressed protein 1 | Authors: | Manjasetty, B.A, Scheich, C, Roske, Y, Niesen, F.H, Gotz, F, Bussow, K, Heinemann, U. | Deposit date: | 2004-07-19 | Release date: | 2005-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1) Bmc Struct.Biol., 5, 2005
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5MNO
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![BU of 5mno by Molmil](/molmil-images/mine/5mno) | Cationic trypsin in complex with N-amidinopiperidine (deuterated sample at 295 K) | Descriptor: | CALCIUM ION, Cationic trypsin, SULFATE ION, ... | Authors: | Schiebel, J, Heine, A, Klebe, G. | Deposit date: | 2016-12-13 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
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5JUG
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![BU of 5jug by Molmil](/molmil-images/mine/5jug) | Structure of an inactive (E45Q) variant of a beta-1,4-mannanase, SsGH134, in complex with Man5 | Descriptor: | CHLORIDE ION, GLYCEROL, alpha-D-mannopyranose, ... | Authors: | Jin, Y, Petricevic, M, Goddard-Borger, E.D, Williams, S.J, Davies, G.J. | Deposit date: | 2016-05-10 | Release date: | 2016-11-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. ACS Cent Sci, 2, 2016
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4R5R
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1LUQ
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4F18
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![BU of 4f18 by Molmil](/molmil-images/mine/4f18) | Subatomic resolution structure of a high affinity periplasmic phosphate-binding protein (PfluDING) bound with arsenate at pH 8.5 | Descriptor: | Putative alkaline phosphatase, hydrogen arsenate | Authors: | Elias, M, Wellner, A, Goldin, K, Chabriere, E, Tawfik, D.S. | Deposit date: | 2012-05-06 | Release date: | 2012-09-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | The molecular basis of phosphate discrimination in arsenate-rich environments. Nature, 491, 2012
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8AQP
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