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7UXI
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BU of 7uxi by Molmil
Structure of CDK2 in complex with FP19711, a Helicon Polypeptide
Descriptor: AMINO GROUP, Cyclin-dependent kinase 2, FP19711, ...
Authors:Li, K, Agarwal, S, Tokareva, O, Thomson, T, Wahl, S, Verdine, G, McGee, J.
Deposit date:2022-05-05
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UY2
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BU of 7uy2 by Molmil
Structure of RNF31 in complex with FP06649, a Helicon Polypeptide
Descriptor: AMINO GROUP, E3 ubiquitin-protein ligase RNF31, Helicon FP06649, ...
Authors:Agarwal, S, Thomson, T, Wahl, S, Walkup, W, Olsen, T, Verdine, G, McGee, J.
Deposit date:2022-05-06
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UXM
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BU of 7uxm by Molmil
Structure of PPIA in complex with FP29092, a Helicon Polypeptide
Descriptor: 1,2-ETHANEDIOL, AMINO GROUP, FP29092, ...
Authors:Li, K, Agarwal, S, Tokareva, O, Thomson, T, Wahl, S, Verdine, G, McGee, J.
Deposit date:2022-05-05
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UX5
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BU of 7ux5 by Molmil
Structure of PDL1 in complex with FP28136, a Helicon Polypeptide
Descriptor: Helicon FP28136, N,N'-(1,4-phenylene)diacetamide, Programmed cell death 1 ligand 1
Authors:Agarwal, S, Li, K, Tokareva, O, Thomson, T, Travaline, T, Wahl, S, Verdine, G, McGee, J.
Deposit date:2022-05-05
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UXJ
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BU of 7uxj by Molmil
Structure of PPIA in complex with FP29102, a Helicon Polypeptide
Descriptor: AMINO GROUP, FP29102, N,N'-(1,4-phenylene)diacetamide, ...
Authors:Li, K, Agarwal, S, Tokareva, O, Thomson, T, Wahl, S, Verdine, G, McGee, J.
Deposit date:2022-05-05
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UYJ
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BU of 7uyj by Molmil
Structure of RNF31 in complex with FP06652, a Helicon Polypeptide
Descriptor: AMINO GROUP, E3 ubiquitin-protein ligase RNF31, Helicon FP06652, ...
Authors:Agarwal, S, Thomson, T, Wahl, S, Walkup, W, Olsen, T, Verdine, G, McGee, J.
Deposit date:2022-05-06
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UXN
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BU of 7uxn by Molmil
Structure of PPIA in complex with FP29103, a Helicon Polypeptide
Descriptor: FP29103, N,N'-(1,4-phenylene)diacetamide, Peptidyl-prolyl cis-trans isomerase A
Authors:Li, K, Agarwal, S, Tokareva, O, Thomson, T, Tattersfield, H, Wahl, S, Verdine, G, McGee, J.
Deposit date:2022-05-05
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VG7
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BU of 7vg7 by Molmil
Plexin B1 extracellular fragment in complex with lasso-grafted PB1m6A9 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, TRIETHYLENE GLYCOL, ...
Authors:Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J.
Deposit date:2021-09-14
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.
Structure, 30, 2022
7VF3
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BU of 7vf3 by Molmil
Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Plexin-B1, ...
Authors:Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J.
Deposit date:2021-09-10
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.
Structure, 30, 2022
6FC9
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BU of 6fc9 by Molmil
The 1,8-bis(aminomethyl)anthracene and Quadruplex-duplex junction complex
Descriptor: DNA (27-MER), [8-(azaniumylmethyl)anthracen-1-yl]methylazanium
Authors:Santana, A, Serrano, I, Montalvillo-Jimenez, L, Corzana, F, Bastida, A, Jimenez-Barbero, J, Gonzalez, C, Asensio, J.L.
Deposit date:2017-12-20
Release date:2019-04-10
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.
Chemistry, 2020
1PG5
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BU of 1pg5 by Molmil
CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS
Descriptor: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J.
Deposit date:2003-05-27
Release date:2004-06-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
3TRO
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BU of 3tro by Molmil
Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A
Descriptor: Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:de Souza, A.L, Pinheiro, M.P, Nonato, M.C.
Deposit date:2011-09-09
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A
To be Published
3TJX
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BU of 3tjx by Molmil
Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant H174A
Descriptor: Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:de Souza, A.L, Nonato, M.C, Pinheiro, M.P.
Deposit date:2011-08-25
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant H174A
To be Published
6FJS
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BU of 6fjs by Molmil
Proteinase~K SIRAS phased structure of room-temperature, serially collected synchrotron data
Descriptor: CALCIUM ION, Proteinase K
Authors:Botha, S, Baitan, D, Jungnickel, K.E.J, Oberthuer, D, Schmidt, C, Stern, S, Wiedorn, M.O, Perbandt, M, Chapman, H.N, Betzel, C.
Deposit date:2018-01-23
Release date:2018-10-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:De novoprotein structure determination by heavy-atom soaking in lipidic cubic phase and SIRAS phasing using serial synchrotron crystallography.
IUCrJ, 5, 2018
7PTF
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BU of 7ptf by Molmil
Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with novobiocin
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA gyrase subunit B, ...
Authors:Cotman, A.E, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P, Mundy, J.E.A, Stevenson, C.E.M, Burton, N, Lawson, D.M, Maxwell, A, Kikelj, D.
Deposit date:2021-09-27
Release date:2022-10-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
J.Med.Chem., 66, 2023
7PQI
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BU of 7pqi by Molmil
Acinetobacter baumannii DNA gyrase B 23kDa ATPase subdomain complexed with novobiocin
Descriptor: 1,2-ETHANEDIOL, DNA gyrase subunit B, NOVOBIOCIN
Authors:Cotman, A.E, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P, Mundy, J.E.A, Stevenson, C.E.M, Burton, N, Lawson, D.M, Maxwell, A, Kikelj, D.
Deposit date:2021-09-17
Release date:2022-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
J.Med.Chem., 66, 2023
7OCL
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BU of 7ocl by Molmil
K1K1, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic
Descriptor: Hepatocyte growth factor alpha chain,Hepatocyte growth factor alpha chain
Authors:de Jonge, H, de Nola, G, Gherardi, E.
Deposit date:2021-04-27
Release date:2021-07-21
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist.
Life Sci Alliance, 5, 2022
8WAV
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BU of 8wav by Molmil
De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAZ
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BU of 8waz by Molmil
De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAX
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BU of 8wax by Molmil
De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAW
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BU of 8waw by Molmil
De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAY
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BU of 8way by Molmil
De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAT
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BU of 8wat by Molmil
De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WB0
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BU of 8wb0 by Molmil
De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAU
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BU of 8wau by Molmil
De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023

222926

數據於2024-07-24公開中

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