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6ZC3
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BU of 6zc3 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
Descriptor: 1,2-ETHANEDIOL, 5-fluoranyl-2-(methylsulfonylamino)benzoic acid, Dishevelled, ...
Authors:Roske, Y, Heinemann, U, Oschkinat, H.
Deposit date:2020-06-09
Release date:2021-06-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
6ZC6
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BU of 6zc6 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
Descriptor: 1,2-ETHANEDIOL, 5-bromanyl-2-(naphthalen-2-ylsulfonylamino)benzoic acid, Segment polarity protein dishevelled homolog DVL-3
Authors:Roske, Y, Heinemann, U, Oschkinat, H.
Deposit date:2020-06-09
Release date:2021-06-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
6ZC8
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BU of 6zc8 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
Descriptor: 2-[[3-chloranyl-4-[(1~{H}-indazol-3-ylcarbonylamino)methyl]phenyl]sulfonylamino]-5-methyl-benzoic acid, Segment polarity protein dishevelled homolog DVL-3
Authors:Roske, Y, Heinemann, U, Oschkinat, H.
Deposit date:2020-06-10
Release date:2021-06-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
6ZC4
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BU of 6zc4 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
Descriptor: 5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ...
Authors:Roske, Y, Heinemann, U, Oschkinat, H.
Deposit date:2020-06-09
Release date:2021-06-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
7LUL
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BU of 7lul by Molmil
Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S.
Deposit date:2021-02-22
Release date:2021-07-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
J.Mol.Biol., 433, 2021
7JZR
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BU of 7jzr by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAEB
Descriptor: 4-(2-aminoethyl)benzoic acid, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALAEB peptide core
Authors:Gill, N.P, Madden, D.R.
Deposit date:2020-09-02
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAEB
To Be Published
7JZO
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BU of 7jzo by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALTPP
Descriptor: 3-(thiophen-2-yl)propanoic acid, GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, ...
Authors:Gill, N.P, Madden, D.R.
Deposit date:2020-09-02
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALTPP
To Be Published
7JZQ
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BU of 7jzq by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALPMB
Descriptor: 4-[(piperidin-1-yl)methyl]benzoic acid, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALPMB peptide core
Authors:Gill, N.P, Madden, D.R.
Deposit date:2020-09-02
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALPMB
To Be Published
7MFW
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BU of 7mfw by Molmil
Drosophila melanogaster Canoe PDZ domain in complex with Echinoid C-terminal region
Descriptor: Canoe,Echinoid
Authors:Slep, K.C, Peifer, M, Byrnes, A.E.
Deposit date:2021-04-11
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis.
J.Cell Biol., 220, 2021
7E0B
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BU of 7e0b by Molmil
The crystal structure of sorting nexin 27 and PBM complex
Descriptor: PBM, Sorting nexin-27
Authors:Shang, G.J, Qi, J.X.
Deposit date:2021-01-27
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Proc.Natl.Acad.Sci.USA, 119, 2022
7JZP
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BU of 7jzp by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALBF
Descriptor: 1-benzofuran-2-carboxylic acid, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALBF peptide core
Authors:Gill, N.P, Madden, D.R.
Deposit date:2020-09-02
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALBF
To Be Published
7VZE
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BU of 7vze by Molmil
Crystal structure of PTPN4 PDZ bound to the PBM of HPV16 E6
Descriptor: Tyrosine-protein phosphatase non-receptor type 4, the PDZ-binding motif of HPV16 E6
Authors:Lee, H.S, Yun, H.-Y, Ku, B.
Deposit date:2021-11-16
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.882 Å)
Cite:Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein.
J.Microbiol, 60, 2022
7QTU
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BU of 7qtu by Molmil
Structural biology of the NS1 avian influenza protein subversion on the Scribble cell polarity module
Descriptor: Non-structural protein 1, Protein scribble homolog
Authors:Javorsky, A, Humbert, P.O, Kvansakul, M.
Deposit date:2022-01-16
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structural Basis of the Avian Influenza NS1 Protein Interactions with the Cell Polarity Regulator Scribble.
Viruses, 14, 2022
7QTP
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BU of 7qtp by Molmil
Structural biology of the NS1 avian influenza protein subversion on the Scribble cell polarity module
Descriptor: Non-structural protein 1, Protein scribble homolog
Authors:Javorsky, A, Humbert, P.O, Kvansakul, M.
Deposit date:2022-01-15
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of the Avian Influenza NS1 Protein Interactions with the Cell Polarity Regulator Scribble.
Viruses, 14, 2022
7QTO
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BU of 7qto by Molmil
Structural biology of the NS1 avian influenza protein subversion on the Scribble cell polarity module
Descriptor: Non-structural protein 1, Protein scribble homolog
Authors:Javorsky, A, Humbert, P.O, Kvansakul, M.
Deposit date:2022-01-15
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis of the Avian Influenza NS1 Protein Interactions with the Cell Polarity Regulator Scribble.
Viruses, 14, 2022
7QCS
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BU of 7qcs by Molmil
PALS1/MPP5 PDZ domain in complex with SARS-CoV-2_E PBM peptide
Descriptor: Envelope small membrane protein, Protein PALS1
Authors:Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C.
Deposit date:2021-11-25
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Front Microbiol, 13, 2022
7QQL
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BU of 7qql by Molmil
The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1
Descriptor: CALCIUM ION, GLYCEROL, Gamma-2-syntrophin,Annexin A2, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2022-01-10
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7QQN
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BU of 7qqn by Molmil
The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3
Descriptor: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2022-01-10
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7QQM
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BU of 7qqm by Molmil
The PDZ domain of LRRC7 fused with ANXA2
Descriptor: CALCIUM ION, GLYCEROL, Leucine-rich repeat-containing protein 7,Annexin A2
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2022-01-10
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7QCT
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BU of 7qct by Molmil
PDZ2 of LNX2 with SARS-CoV-2_E PBM complex
Descriptor: Envelope small membrane protein, Ligand of Numb protein X 2
Authors:Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C.
Deposit date:2021-11-25
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Front Microbiol, 13, 2022
7QCR
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BU of 7qcr by Molmil
MLLT4/Afadin PDZ domain in complex with the C-terminal peptide from protein E of SARS-CoV-2
Descriptor: Afadin, Envelope small membrane protein, SULFATE ION
Authors:Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C.
Deposit date:2021-11-25
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Front Microbiol, 13, 2022
7PCB
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BU of 7pcb by Molmil
The PDZ domain of SNX27 fused with ANXA2
Descriptor: CALCIUM ION, GLYCEROL, Sorting nexin-27,Annexin A2
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC9
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BU of 7pc9 by Molmil
The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1
Descriptor: CALCIUM ION, Protein Tax-1, Synaptojanin-2-binding protein,Annexin A2
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC3
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BU of 7pc3 by Molmil
The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1
Descriptor: CALCIUM ION, Disks large homolog 1,Annexin A2, GLYCEROL, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC5
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BU of 7pc5 by Molmil
The third PDZ domain of PDZD7 complexed with the PDZ-binding motif of EXOC4
Descriptor: CALCIUM ION, Exocyst complex component 4, GLYCEROL, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022

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數據於2024-06-12公開中

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