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3AZR
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Diverse Substrates Recognition Mechanism Revealed by Thermotoga maritima Cel5A Structures in Complex with Cellobiose
Descriptor: Endoglucanase, beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Wu, T.H, Huang, C.H, Ko, T.P, Lai, H.L, Ma, Y, Chen, C.C, Cheng, Y.S, Liu, J.R, Guo, R.T.
Deposit date:2011-05-30
Release date:2011-08-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose
Biochim.Biophys.Acta, 1814, 2011
3AZS
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Diverse Substrates Recognition Mechanism Revealed by Thermotoga maritima Cel5A Structures in Complex with Mannotriose
Descriptor: Endoglucanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose
Authors:Wu, T.H, Huang, C.H, Ko, T.P, Lai, H.L, Ma, Y, Chen, C.C, Cheng, Y.S, Liu, J.R, Guo, R.T.
Deposit date:2011-05-30
Release date:2011-08-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose
Biochim.Biophys.Acta, 1814, 2011
4W80
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Tetrameric BAP29 vDED with disulfide bonds in crystal contacts
Descriptor: B-cell receptor-associated protein 29, SULFATE ION
Authors:Quistgaard, E.M.
Deposit date:2014-08-22
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A disulfide polymerized protein crystal.
Chem.Commun.(Camb.), 50, 2014
6JI1
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BU of 6ji1 by Molmil
Tetrameric PepTSo2 incorporated in salipro nano particle
Descriptor: Proton:oligopeptide symporter POT family
Authors:Kawamoto, A, Matoba, K, Takagi, J.
Deposit date:2019-02-19
Release date:2019-05-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2.
Acta Crystallogr.,Sect.F, 75, 2019
5GYR
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BU of 5gyr by Molmil
Tetrameric Allochromatium vinosum cytochrome c'
Descriptor: Cytochrome c', HEME C
Authors:Yamanaka, M, Hoshizumi, M, Nagao, S, Nakayama, R, Shibata, N, Higuchi, Y, Hirota, S.
Deposit date:2016-09-23
Release date:2017-02-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Formation and carbon monoxide-dependent dissociation of Allochromatium vinosum cytochrome c' oligomers using domain-swapped dimers
Protein Sci., 26, 2017
5KTL
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BU of 5ktl by Molmil
Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis.
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, MANGANESE (II) ION
Authors:Christensen, J.B, Panjikar, S, Perugini, M.
Deposit date:2016-07-11
Release date:2016-11-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure and Function of Cyanobacterial DHDPS and DHDPR.
Sci Rep, 6, 2016
5UGJ
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BU of 5ugj by Molmil
Crystal structure of HTPA Reductase from neisseria meningitidis
Descriptor: 4-hydroxy-tetrahydrodipicolinate reductase
Authors:Keown, J.K, Richards, E.W, Pearce, F.G, Goldstone, D.C.
Deposit date:2017-01-08
Release date:2017-12-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly.
Biochem. J., 475, 2018
5UA0
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BU of 5ua0 by Molmil
Dimeric crystal structure of HTPA reductase from arabidopsis thaliana
Descriptor: 4-hydroxy-tetrahydrodipicolinate reductase 2, chloroplastic, SULFATE ION
Authors:Keown, J.K, Pearce, F.G, Goldstone, D.C.
Deposit date:2016-12-18
Release date:2017-12-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly.
Biochem. J., 475, 2018
1Q7Q
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BU of 1q7q by Molmil
Cobalamin-dependent methionine synthase (1-566) from T. maritima (Oxidized, Orthorhombic)
Descriptor: 5-methyltetrahydrofolate S-homocysteine methyltransferase
Authors:Evans, J.C, Huddler, D.P, Hilgers, M.T, Romanchuk, G, Matthews, R.G, Ludwig, M.L.
Deposit date:2003-08-19
Release date:2004-03-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1Q7M
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Cobalamin-dependent methionine synthase (MetH) from Thermotoga maritima (Oxidized, Monoclinic)
Descriptor: 5-methyltetrahydrofolate S-homocysteine methyltransferase
Authors:Evans, J.C, Huddler, D.P, Hilgers, M.T, Romanchuk, G, Matthews, R.G, Ludwig, M.L.
Deposit date:2003-08-19
Release date:2004-03-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1QFG
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BU of 1qfg by Molmil
E. COLI FERRIC HYDROXAMATE RECEPTOR (FHUA)
Descriptor: 3-HYDROXY-TETRADECANOIC ACID, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, DIPHOSPHATE, ...
Authors:Ferguson, A.D, Welte, W, Hofmann, E, Lindner, B, Holst, O, Coulton, J.W, Diederichs, K.
Deposit date:1999-04-10
Release date:2000-07-26
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins.
Structure Fold.Des., 8, 2000
1QJQ
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FERRIC HYDROXAMATE RECEPTOR FROM ESCHERICHIA COLI (FHUA)
Descriptor: 3-HYDROXY-TETRADECANOIC ACID, DIPHOSPHATE, FERRIC HYDROXAMATE RECEPTOR, ...
Authors:Ferguson, A.D, Braun, V, Fiedler, H.-P, Coulton, J.W, Diederichs, K, Welte, W.
Deposit date:1999-06-29
Release date:2000-06-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA.
Protein Sci., 9, 2000
1Z9W
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BU of 1z9w by Molmil
Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
Descriptor: Dihydroneopterin aldolase
Authors:Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-04-05
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
6EUE
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BU of 6eue by Molmil
Rivastigmine analogue bound to Tc ACHE.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, PENTAETHYLENE GLYCOL
Authors:De la Mora, E, Brazzolotto, X, Dighe, S.N, Silman, I, Weik, M, Ross, B.
Deposit date:2017-10-30
Release date:2018-11-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model
Commun Chem, 2019
6EWK
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T. californica AChE in complex with a 3-hydroxy-2-pyridine aldoxime.
Descriptor: 2-[(~{E})-hydroxyiminomethyl]-6-(5-morpholin-4-ylpentyl)pyridin-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:de la Mora, E, Weik, M, Braiki, A, Mougeot, R, Jean, L, Renard, P.I.
Deposit date:2017-11-04
Release date:2018-11-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration.
Chemistry, 24, 2018
6EZG
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BU of 6ezg by Molmil
Torpedo californica AChE in complex with indolic multi-target directed ligand
Descriptor: 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(phenylmethyl)piperidin-4-yl]propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:Santoni, G, Lalut, J, Karila, D, Lecoutey, C, Davis, A, Nachon, F, Sillman, I, Sussman, J, Weik, M, Maurice, T, Dallemagne, P, Rochais, C.
Deposit date:2017-11-15
Release date:2018-11-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase.
Eur J Med Chem, 162, 2018
7B38
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BU of 7b38 by Molmil
Torpedo californica acetylcholinesterase complexed with Mg+2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:Silman, I, Shnyrov, V.L, Ashani, Y, Roth, E, Nicolas, A, Sussman, J.L, Weiner, L.
Deposit date:2020-11-29
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif.
Protein Sci., 30, 2021
7B2W
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BU of 7b2w by Molmil
Torpedo californica acetylcholinesterase complexed with UO2
Descriptor: Acetylcholinesterase, URANYL (VI) ION
Authors:Silman, I, Shnyrov, V.L, Ashani, Y, Roth, E, Nicolas, A, Sussman, J.L, Weiner, L.
Deposit date:2020-11-28
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif.
Protein Sci., 30, 2021
6PIK
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BU of 6pik by Molmil
Tetrameric cryo-EM ArnA
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
6YUP
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BU of 6yup by Molmil
Heterotetrameric structure of the rBAT-b(0,+)AT1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT, ...
Authors:Wu, D, Safarian, S, Michel, H.
Deposit date:2020-04-27
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for amino acid exchange by a human heteromeric amino acid transporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
3C63
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BU of 3c63 by Molmil
Tetrameric Cytochrome cb562 (K34/H59/D62/H63/H73/A74/H77) Assembly Stabilized by Interprotein Zinc Coordination
Descriptor: CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562, ...
Authors:Tezcan, F.A, Salgado, E.N, Lewis, R.A, Faraone-Mennella, J.
Deposit date:2008-02-02
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Metal-mediated self-assembly of protein superstructures: influence of secondary interactions on protein oligomerization and aggregation.
J.Am.Chem.Soc., 130, 2008
1Q7Z
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BU of 1q7z by Molmil
Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima (Cd2+ complex)
Descriptor: 5-methyltetrahydrofolate S-homocysteine methyltransferase, CADMIUM ION
Authors:Evans, J.C, Huddler, D.P, Hilgers, M.T, Romanchuk, G, Matthews, R.G, Ludwig, M.L.
Deposit date:2003-08-20
Release date:2004-03-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1SN9
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An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein
Descriptor: tetrameric beta-beta-alpha mini-protein
Authors:Ali, M.H, Peisach, E, Allen, K.N, Imperiali, B.
Deposit date:2004-03-10
Release date:2004-08-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray structure analysis of a designed oligomeric miniprotein reveals a discrete quaternary architecture
Proc.Natl.Acad.Sci.USA, 101, 2004
6NSN
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TetR family transcriptional regulator CifR C99T-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Descriptor: DNA (26-MER), GLYCEROL, TetR family transcriptional regulator CifR
Authors:He, S, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024
6NSM
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TetR family transcriptional regulator CifR C99T-C107S-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Descriptor: DNA (26-MER), TetR family transcriptional regulator CifR
Authors:He, S, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024

223532

數據於2024-08-07公開中

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