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4FOW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-ammoniopropane-1-sulfonate Descriptor: 3-aminopropane-1-sulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOY	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-(Benzylammonio)ethanesulfonate Descriptor: 2-(benzylamino)ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.843 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPH	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Fluorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-fluorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.938 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPK	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-methylbenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-methylbenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPF	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Chlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-chlorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4YW5	Crystal Structure of Streptococcus pneumoniae NanC, complex with oseltamivir carboxylate Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, GLYCEROL, ... Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YW3	Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with Neu5Ac2en Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, N-acetyl-alpha-neuraminic acid, ... Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YW4	Streptococcus pneumoniae sialidase NanC Descriptor: GLYCEROL, Neuraminidase C, PHOSPHATE ION Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of a novel sialidase To be published
4YZ4	Crystal Structure of Streptococcus pneumoniae NanC, in complex with N-Acetylneuraminic acid. Descriptor: N-acetyl-alpha-neuraminic acid, SULFATE ION, Sialidase, ... Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2015-09-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YZ3	Crystal Structure of Streptococcus pneumoniae NanC, in complex with Oseltamivir. Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase, SULFATE ION Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2016-04-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal Structure of Streptococcus pneumoniae NanC. To Be Published
4YZ2	Crystal Structure of Streptococcus pneumoniae NanC, in complex with 2-deoxy-2,3-didehydro-N-acetylneuraminic acid. Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase NanC Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2015-09-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YZ1	Crystal Structure of Streptococcus pneumoniae NanC, apo structure. Descriptor: Putative neuraminidase, SULFATE ION Authors: Lukacik, P, Owen, D.O, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2015-09-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YW1	Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with 3'SL Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YW2	Crystal Structure of Streptococcus pneumoniae NanC, complex 6'SL Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YZ5	Crystal Structure of Streptococcus pneumoniae NanC, in complex with 3-Sialyllactose Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, Putative neuraminidase, ... Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2015-09-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4FOQ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-aminoethanesulfonic acid Descriptor: 2-AMINOETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FP3	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(Furan-2-ylmethyl)ammonio]sulfonate Descriptor: 2-[(furan-2-ylmethyl)amino]ethanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.743 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPJ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPY	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-bromobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-23 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOV	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-Cyclohexyl-1-propylsulfonic acid Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPC	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Chlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-chlorobenzyl)amino]ethanesulfonic acid, GLYCEROL, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FQ4	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Fluoro-3-methylbenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-fluoro-3-methylbenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-25 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.843 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4XE9	Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2014-12-23 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.84 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XHB	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES Descriptor: (1R,2S)-cyclopentane-1,2-diol, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sialidase B Authors: Brear, P. Deposit date: 2015-01-05 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.88 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... Authors: Brear, P. Deposit date: 2015-01-09 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.53 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published

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