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8ISJ	Pr conformer of Arabidopsis thaliana phytochrome A - AtphyA-Pr Descriptor: 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A Authors: Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. Deposit date: 2023-03-20 Release date: 2023-08-09 Last modified: 2023-10-11 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
8ISK	Pr conformer of Zea mays phytochrome A1 - ZmphyA1-Pr Descriptor: 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome Authors: Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. Deposit date: 2023-03-20 Release date: 2023-08-09 Last modified: 2023-10-11 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
8OYQ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK13 Descriptor: Chemotaxis protein CheA, quinazolin-2-amine Authors: Adhav, A, Marina, A. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK13 To Be Published
8OYZ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 Descriptor: 2-azanyl-7,8-dihydro-6~{H}-quinazolin-5-one, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 To Be Published
8OZ9	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 Descriptor: 7-(1~{H}-1,2,3-triazol-5-yl)quinazolin-2-amine, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-08 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 To Be Published
8P3N	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK8 Descriptor: 9-METHYL-9H-PURIN-6-AMINE, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-18 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK8 To Be Published
8P3R	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK4 Descriptor: 9~{H}-purine, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-18 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK4 To Be Published
8P59	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-333 Descriptor: 7-(2-phenylethoxy)quinazolin-2-amine, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-23 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-333 To Be Published
8PF2	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK16 Descriptor: Chemotaxis protein CheA, RESORCINOL Authors: Adhav, A, Marina, A. Deposit date: 2023-06-15 Release date: 2024-06-26 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity. Microbiol Spectr, 2024
8QDX	E. coli DNA gyrase bound to a DNA crossover Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, DNA minicircle Authors: Vayssieres, M, Lamour, V. Deposit date: 2023-08-30 Release date: 2024-04-10 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of DNA crossover capture by Escherichia coli DNA gyrase. Science, 384, 2024
8QQI	E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800 Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ... Authors: Ghilarov, D, Martin, N.I, van der Stelt, M. Deposit date: 2023-10-04 Release date: 2024-06-19 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nat.Chem., 2024
8QQS	E. coli DNA gyrase bound to a linear part of a DNA minicircle Descriptor: DNA (30-MER), DNA gyrase subunit A, DNA gyrase subunit B Authors: Vayssieres, M, Lamour, V. Deposit date: 2023-10-06 Release date: 2024-04-10 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of DNA crossover capture by Escherichia coli DNA gyrase. Science, 384, 2024
8QQU	Asymetric subunit of E. coli DNA gyrase bound to a linear part of a DNA minicircle Descriptor: DNA (16-MER), DNA gyrase subunit A, DNA gyrase subunit B Authors: Vayssieres, M, Lamour, V. Deposit date: 2023-10-06 Release date: 2024-04-10 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of DNA crossover capture by Escherichia coli DNA gyrase. Science, 384, 2024
8SBM	Crystal structure of the wild-type Catalytic ATP-binding domain of Mtb DosS Descriptor: 1,2-ETHANEDIOL, GAF domain-containing protein, SODIUM ION, ... Authors: Larson, G, Shi, K, Aihara, H, Bhagi-Damodaran, A. Deposit date: 2023-04-03 Release date: 2023-11-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Understanding ATP Binding to DosS Catalytic Domain with a Short ATP-Lid. Biochemistry, 62, 2023
8SGK	CryoEM structure of Deinococcus radiodurans BphP photosensory module in Pr state Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome Authors: Li, H, Li, H. Deposit date: 2023-04-12 Release date: 2024-05-22 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: CryoEM structure of Deinococcus radiodurans BphP photosensory module in Pr state To Be Published
8ZM1	Structure of human pyruvate dehydrogenase kinase 2 complexed with compound 6 Descriptor: (5~{R})-5-propan-2-ylindeno[1,2-b]pyridin-5-ol, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Authors: Akai, S, Orita, T, Nomura, A, Adachi, T. Deposit date: 2024-05-22 Release date: 2024-06-19 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase. Bioorg.Med.Chem.Lett., 109, 2024
8ZM2	Structure of human pyruvate dehydrogenase kinase 2 complexed with compound 16 Descriptor: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial, methyl (9~{R})-9-oxidanyl-9-(trifluoromethyl)fluorene-4-carboxylate Authors: Akai, S, Orita, T, Nomura, A, Adachi, T. Deposit date: 2024-05-22 Release date: 2024-06-19 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase. Bioorg.Med.Chem.Lett., 109, 2024

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