PDB: 658 resultsInfo pagesStatus searchChemie searchBIRD

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6CT4	TFE-induced NMR structure of an antimicrobial peptide (EcDBS1R5) derived from a mercury transporter protein (MerP - Escherichia coli) Descriptor: EcDBS1R5 Authors: Cardoso, M.H, Chan, L.Y, Candido, E.S, Craik, D.J, Franco, O.L. Deposit date: 2018-03-22 Release date: 2018-11-14 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies. ACS Infect Dis, 4, 2018
4A82	Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966. Descriptor: CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Authors: Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C. Deposit date: 2011-11-18 Release date: 2012-01-11 Last modified: 2024-05-08 Method: ELECTRON CRYSTALLOGRAPHY (9 Å) Cite: The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate. J.Biol.Chem., 286, 2011
7KGE	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-II Descriptor: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGI	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-III Descriptor: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.34 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGF	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-III Descriptor: Efflux pump membrane transporter Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGH	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-II Descriptor: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGD	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-I Descriptor: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.64 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGG	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-I Descriptor: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7PHP	Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM Descriptor: Anti-Fab nanobody, Multidrug resistance protein NorM, NabFab HC, ... Authors: Bloch, J.S, Mukherjee, S, Kowal, J, Niederer, M, Pardon, E, Steyaert, J, Kossiakoff, A.A, Locher, K.P. Deposit date: 2021-08-18 Release date: 2021-09-01 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
4ZIT	Crystal structure of AcrB in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-28 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.296 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZIW	Crystal structure of AcrB deletion mutant in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-28 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.399 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZIV	Crystal structure of AcrB triple mutant in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-28 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
7B8S	Fusidic acid bound structure of bacterial efflux pump. Descriptor: DARPin, FUSIDIC ACID, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB Authors: Wilhelm, J, Sjuts, H, Pos, K.M. Deposit date: 2020-12-13 Release date: 2021-10-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
7B8T	Levofloxacin bound structure of bacterial efflux pump. Descriptor: (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB Authors: Wilhelm, J, Sjuts, H, Pos, K.M. Deposit date: 2020-12-13 Release date: 2021-10-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
7B8R	Doxycycline bound structure of bacterial efflux pump. Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, DARPin, DI(HYDROXYETHYL)ETHER, ... Authors: Wilhelm, J, Sjuts, H, Pos, K.M. Deposit date: 2020-12-13 Release date: 2021-10-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
2GHI	Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2 Descriptor: SULFATE ION, transport protein Authors: Dong, A, Gao, M, Choe, J, Zhao, Y, Lew, J, Wasney, G, Alam, Z, Melone, M, Kozieradzki, I, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) Deposit date: 2006-03-27 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
5IHJ	Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii BIDMC57 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, GLYCEROL, ... Authors: Piepenbrink, K.H, Sundberg, E.J. Deposit date: 2016-02-29 Release date: 2016-09-21 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter. J.Biol.Chem., 291, 2016
7OCY	Enterococcus faecalis EfrCD in complex with a nanobody Descriptor: ABC transporter ATP-binding protein, Nanobody Authors: Ehrenbolger, K, Hutter, C.A.J, Meier, G, Seeger, M.A, Barandun, J. Deposit date: 2021-04-28 Release date: 2022-05-18 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.25 Å) Cite: Deep mutational scan of a drug efflux pump reveals its structure-function landscape. Nat.Chem.Biol., 19, 2023
4Q4J	Structure of crosslinked TM287/288_S498C_S520C mutant Descriptor: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 Authors: Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A. Deposit date: 2014-04-14 Release date: 2014-07-16 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
4ZJO	Crystal structure of AcrB triple mutant in complex with antibiotic in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-29 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZJQ	Crystal structure of AcrB deletion mutant in complex with antibiotic in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-29 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.592 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZJL	Crystal structure of AcrB in complex with antibiotic in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-29 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.47 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4Q4H	TM287/288 in its apo state Descriptor: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 Authors: Hohl, M, Gruetter, M.G, Seeger, M.A. Deposit date: 2014-04-14 Release date: 2014-07-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.527 Å) Cite: Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
4DK1	Crystal Structure of MacA-MexA chimeric protein, containing the Pseudomonas aeruginosa MexA alpha-hairpin domain. Descriptor: Putative MacA, Multidrug resistance protein mexA Authors: Xu, Y, Ha, N.C. Deposit date: 2012-02-03 Release date: 2012-03-07 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (3.499 Å) Cite: Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria. J.Biol.Chem., 287, 2012
5CFV	Fusion of Maltose-binding Protein and PilA from Acinetobacter nosocomialis M2 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, MAGNESIUM ION, ... Authors: Piepenbrink, K.H, Sundberg, E.J. Deposit date: 2015-07-08 Release date: 2016-07-13 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter. J.Biol.Chem., 291, 2016

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