PDB: 602 resultsInfo pagesStatus searchChemie searchBIRD

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5N8Z	Crystal Structure of Drosophila DHX36 helicase in complex with CTCTCCCTT Descriptor: CG9323, isoform A, DNA (5'-D(P*CP*TP*CP*TP*CP*CP*CP*TP*T)-3'), ... Authors: Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.477 Å) Cite: Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
5N8U	Crystal Structure of Drosophila DHX36 helicase in complex with CTCTCCT Descriptor: CG9323, isoform A, DNA (5'-D(P*CP*TP*CP*TP*CP*CP*CP*T)-3'), ... Authors: Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
5N9E	Crystal Structure of Drosophila DHX36 helicase in complex with TGGGGATTT Descriptor: CG9323, isoform A, DNA (5'-D(P*TP*GP*GP*GP*GP*AP*TP*TP*T)-3') Authors: Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.007 Å) Cite: Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
5LST	Crystal structure of the human RecQL4 helicase. Descriptor: ATP-dependent DNA helicase Q4, ZINC ION Authors: Kaiser, S, Sauer, F, Kisker, C. Deposit date: 2016-09-05 Release date: 2017-07-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism. Nat Commun, 8, 2017
5M5P	S. cerevisiae spliceosomal helicase Brr2 (271-end) in complex with the Jab/MPN domain of S. cerevisiae Prp8 Descriptor: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 Authors: Becke, C, Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C. Deposit date: 2016-10-22 Release date: 2016-12-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
5N90	Crystal Structure of Drosophila DHX36 helicase in complex with TTGTGGTGT Descriptor: CG9323, isoform A, DNA (5'-D(P*TP*TP*GP*TP*GP*GP*TP*GP*T)-3'), ... Authors: Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.069 Å) Cite: Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
5N8S	Crystal Structure of Drosophila DHX36 helicase in complex with polyT Descriptor: CG9323, isoform A, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... Authors: Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
5N96	Crystal Structure of Drosophila DHX36 helicase in complex with AGGGTTTTTT Descriptor: CG9323, isoform A, DNA (5'-D(P*AP*GP*GP*GP*TP*TP*TP*TP*TP*T)-3'), ... Authors: Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.716 Å) Cite: Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
6CRM	Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex Descriptor: DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3'), RecQ, ZINC ION Authors: Voter, A.F, Keck, J.L. Deposit date: 2018-03-19 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.19286251 Å) Cite: A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases. Nat Commun, 9, 2018
6CZ5	Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C Descriptor: 5'-O-[(R)-hydroxy(propanoylamino)phosphoryl]adenosine, ATP-dependent RNA helicase DDX3X Authors: Barkovich, K.J, Moore, M.K, Hu, Q, Shokat, K.M. Deposit date: 2018-04-08 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3 Å) Cite: Chemical genetic inhibition of DEAD-box proteins using covalent complementarity. Nucleic Acids Res., 46, 2018
6D6R	Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ... Authors: Weick, E.-M, Lima, C.D. Deposit date: 2018-04-22 Release date: 2018-06-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173, 2018
6ZM2	Crystal structure of the DEAH-box ATPase Prp2 in complex with ADP-BeF3 and ssRNA Descriptor: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Hamann, F, Ficner, R. Deposit date: 2020-07-01 Release date: 2021-04-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases. Acta Crystallogr D Struct Biol, 77, 2021
6ZWX	Crystal structure of E. coli RNA helicase HrpA Descriptor: ATP-dependent RNA helicase HrpA Authors: Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. Deposit date: 2020-07-29 Release date: 2021-06-30 Last modified: 2021-08-04 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZWW	Crystal structure of E. coli RNA helicase HrpA in complex with RNA Descriptor: ATP-dependent RNA helicase HrpA, CALCIUM ION, ssRNA Authors: Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. Deposit date: 2020-07-29 Release date: 2021-06-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
7A8R	Structure of RecQL from Bos taurus Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, MAGNESIUM ION, ... Authors: Rety, S, Chen, W.F, Xi, X.G. Deposit date: 2020-08-30 Release date: 2021-10-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Endogenous Bos taurus RECQL is predominantly monomeric and more active than oligomers. Cell Rep, 36, 2021
7AUD	Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ... Authors: Chen, X, Oliver, A.W. Deposit date: 2020-11-02 Release date: 2020-12-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.96 Å) Cite: Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. Elife, 10, 2021
7AUC	Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM) Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Chen, X, Oliver, A.W. Deposit date: 2020-11-02 Release date: 2020-12-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. Elife, 10, 2021
7AQO	yeast THO-Sub2 complex dimer Descriptor: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... Authors: Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. Deposit date: 2020-10-22 Release date: 2020-12-02 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
7APX	yeast THO-Sub2 complex Descriptor: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... Authors: Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. Deposit date: 2020-10-20 Release date: 2020-12-02 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
7APK	Structure of the human THO - UAP56 complex Descriptor: Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... Authors: Hohmann, U, Puehringer, T, Plaschka, C. Deposit date: 2020-10-17 Release date: 2020-12-16 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure of the human core transcription-export complex reveals a hub for multivalent interactions. Elife, 9, 2020
7ASK	43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kDDX60 Authors: Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. Deposit date: 2020-10-27 Release date: 2021-04-14 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
7AKP	Crystal structure of E. coli RNA helicase HrpA-D305A Descriptor: ATP-dependent RNA helicase HrpA Authors: Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. Deposit date: 2020-10-01 Release date: 2021-06-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZNS	Crystal Structure of DUF1998 helicase MrfA Descriptor: Uncharacterized ATP-dependent helicase YprA, ZINC ION Authors: Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. Deposit date: 2020-07-06 Release date: 2020-11-25 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.32 Å) Cite: A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
6ZNP	Crystal Structure of DUF1998 helicase MrfA bound to DNA Descriptor: CITRIC ACID, Uncharacterized ATP-dependent helicase YprA, ZINC ION, ... Authors: Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. Deposit date: 2020-07-06 Release date: 2020-11-25 Last modified: 2021-01-20 Method: X-RAY DIFFRACTION (3.16 Å) Cite: A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
6ZNQ	Crystal Structure of DUF1998 helicase MrfA bound to DNA and AMPPNP Descriptor: CITRIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Uncharacterized ATP-dependent helicase YprA, ... Authors: Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. Deposit date: 2020-07-06 Release date: 2020-11-25 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.34 Å) Cite: A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021

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