6GT0
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![BU of 6gt0 by Molmil](/molmil-images/mine/6gt0) | Nitrite-bound copper nitrite reductase from Achromobacter cycloclastes determined by serial femtosecond rotation crystallography | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, MALONATE ION, ... | Authors: | Halsted, T.P, Yamashita, K, Gopalasingam, C.C, Shenoy, R.T, Hirata, K, Ago, H, Ueno, G, Eady, R.R, Antonyuk, S.V, Yamamoto, M, Hasnain, S.S. | Deposit date: | 2018-06-15 | Release date: | 2019-07-03 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography. Iucrj, 6, 2019
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6D7G
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![BU of 6d7g by Molmil](/molmil-images/mine/6d7g) | Structure of 5F3 TCR in complex with HLA-A2/MART-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MART1 PEPTIDE-BETA-2-MICROGLOBULIN-HLA-A*02 CHIMERA, T-CELL RECEPTOR GAMMA VARIABLE 8,T-CELL RECEPTOR GAMMA-2 CHAIN C REGION, ... | Authors: | Roy, S, Adams, E.J. | Deposit date: | 2018-04-24 | Release date: | 2019-01-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells. Sci Immunol, 3, 2018
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8XW6
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![BU of 8xw6 by Molmil](/molmil-images/mine/8xw6) | Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and ATP | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nakashima, R, Taguchi, A. | Deposit date: | 2024-01-16 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural Basis of Nucleotide Selectivity in Pyruvate Kinase. J.Mol.Biol., 436, 2024
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6P2V
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![BU of 6p2v by Molmil](/molmil-images/mine/6p2v) | RebH Variant 10S, Tryptamine 5-halogenase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent tryptophan halogenase RebH | Authors: | Andorfer, M.C, Sukumar, N, Lewis, J.C. | Deposit date: | 2019-05-22 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.553 Å) | Cite: | Structural and Computational Analysis of Laboratory-Evolved Halogenases Reveals Molecular Details of Site-Selectivity To Be Published
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5J4E
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![BU of 5j4e by Molmil](/molmil-images/mine/5j4e) | |
8BBI
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![BU of 8bbi by Molmil](/molmil-images/mine/8bbi) | |
5JKN
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![BU of 5jkn by Molmil](/molmil-images/mine/5jkn) | Crystal structure of deubiquitinase MINDY-1 | Descriptor: | DI(HYDROXYETHYL)ETHER, MERCURY (II) ION, PHOSPHATE ION, ... | Authors: | Abdul Rehman, S.A, Kulathu, Y. | Deposit date: | 2016-04-26 | Release date: | 2016-06-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol.Cell, 63, 2016
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2NLS
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6GAY
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![BU of 6gay by Molmil](/molmil-images/mine/6gay) | |
8WYY
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6FTB
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![BU of 6ftb by Molmil](/molmil-images/mine/6ftb) | Staphylococcus aureus monofunctional glycosyltransferase in complex with moenomycin | Descriptor: | (2R)-2,3-dihydroxypropyl dodecanoate, 1,2-ETHANEDIOL, MOENOMYCIN, ... | Authors: | Punekar, A.S, Dowson, C.J, Roper, D.I. | Deposit date: | 2018-02-20 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization. Cell Surf, 2, 2018
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8WYU
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![BU of 8wyu by Molmil](/molmil-images/mine/8wyu) | |
8BG2
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6P6W
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![BU of 6p6w by Molmil](/molmil-images/mine/6p6w) | Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | Descriptor: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | Authors: | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | Deposit date: | 2019-06-04 | Release date: | 2019-08-14 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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8WYT
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![BU of 8wyt by Molmil](/molmil-images/mine/8wyt) | Partially closed Falcilysin bound to MK-4815, from MK-4815-treated dataset | Descriptor: | 2-(aminomethyl)-3,5-ditert-butyl-phenol, Falcilysin, ZINC ION | Authors: | Lin, J.Q, Yan, X.F, Lescar, J. | Deposit date: | 2023-10-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Partially closed Falcilysin bound to MK-4815, from MK-4815-treated dataset To Be Published
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6D86
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![BU of 6d86 by Molmil](/molmil-images/mine/6d86) | Structure of the Bovine p85a BH domain | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION | Authors: | Moore, S.A, Marshall, J.D, Anderson, D.H. | Deposit date: | 2018-04-25 | Release date: | 2018-05-23 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation. Sci Rep, 8, 2018
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8Y7F
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6GC2
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![BU of 6gc2 by Molmil](/molmil-images/mine/6gc2) | AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface | Descriptor: | Heavy chain, Light Chain | Authors: | Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J. | Deposit date: | 2018-04-17 | Release date: | 2019-05-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces. Plos Comput.Biol., 15, 2019
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6FU1
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![BU of 6fu1 by Molmil](/molmil-images/mine/6fu1) | Crystal structure of Schistosoma mansoni HDAC8 complexed with a n-alkyl hydroxamate | Descriptor: | GLYCEROL, Histone deacetylase, POTASSIUM ION, ... | Authors: | Marek, M, Shaik, T.B, Romier, C. | Deposit date: | 2018-02-26 | Release date: | 2019-03-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.548 Å) | Cite: | A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing. Molecules, 23, 2018
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6DJE
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![BU of 6dje by Molmil](/molmil-images/mine/6dje) | Crystal structure of Tdp1 catalytic domain in complex with Sigma Aldrich compound CDS010292 | Descriptor: | 1,2-ETHANEDIOL, 4-hydroxy-8-(propan-2-yl)quinoline-3-carboxylic acid, Tyrosyl-DNA phosphodiesterase 1 | Authors: | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | Deposit date: | 2018-05-25 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.705 Å) | Cite: | Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening. Nucleic Acids Res., 47, 2019
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6FUN
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8WYX
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6DLF
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![BU of 6dlf by Molmil](/molmil-images/mine/6dlf) | Crystal structure of NTRI homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotrimin | Authors: | Ranaivoson, F.M, Turk, L.S, Ozkan, E, Montelione, G.T, Comoletti, D. | Deposit date: | 2018-06-01 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.446 Å) | Cite: | Structure of a heterodimer of neuronal cell surface proteins Structure, 2019
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6PJU
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6FYG
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![BU of 6fyg by Molmil](/molmil-images/mine/6fyg) | The crystal structure of EncM V135T mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM | Authors: | Saleem-Batcha, R, Teufel, R. | Deposit date: | 2018-03-11 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Enzymatic control of dioxygen binding and functionalization of the flavin cofactor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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