PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

---

1QSS	DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', ... Authors: Li, Y, Mitaxov, V, Waksman, G. Deposit date: 1999-06-23 Release date: 1999-08-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
8B79	The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site Descriptor: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... Authors: Parkash, V, Johansson, E. Deposit date: 2022-09-29 Release date: 2023-10-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.65 Å) Cite: A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
1QSY	DDATP-Trapped closed ternary complex of the large fragment of DNA Polymerase I from thermus aquaticus Descriptor: 2',3'-dideoxyadenosine triphosphate, 5'-D(*AP*TP*TP*GP*CP*GP*CP*CP*TP*P*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3', ... Authors: Li, Y, Mitaxov, V, Waksman, G. Deposit date: 1999-06-24 Release date: 1999-08-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
7RBH	Human DNA polymerase beta crosslinked ternary complex 2 Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, CALCIUM ION, ... Authors: Kumar, A. Deposit date: 2021-07-06 Release date: 2022-03-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
7RBG	Human DNA polymerase beta crosslinked ternary complex 1 Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, CALCIUM ION, ... Authors: Reed, A.J, Kumar, A. Deposit date: 2021-07-06 Release date: 2022-03-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
4KGK	Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Thg1-like uncharacterized protein Authors: Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S. Deposit date: 2013-04-29 Release date: 2013-08-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites. Plos One, 8, 2013
6BTF	DNA Polymerase Beta I260Q Ternary Complex Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA Downstream Strand, DNA Primer Strand, ... Authors: Eckenroth, B.E, Doublie, S. Deposit date: 2017-12-06 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.75 Å) Cite: I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
2KTZ	Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA Descriptor: (7R)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine, HCV IRES Domain IIa RNA Authors: Paulsen, R.B, Seth, P.P, Swayze, E.E, Griffey, R.H, Skalicky, J.J, Cheatham III, T.E, Davis, D.R. Deposit date: 2010-02-10 Release date: 2010-04-28 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Inhibitor-induced structural change in the HCV IRES domain IIa RNA. Proc.Natl.Acad.Sci.USA, 107, 2010
7ZUS	Crystal structure of ternary complex of Pol theta polymerase domain Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*(DDG))-3'), DNA (5'-D(P*TP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*C)-3'), ... Authors: Krajewski, W.W, Turnbull, A.P, Willis, S, Charles, M, Stockley, M, Heald, R.A. Deposit date: 2022-05-13 Release date: 2022-10-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta. J.Med.Chem., 65, 2022
3L0C	Crystal structure of SCP1 phosphatase D206A mutant with trapped inorganic phosphate Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, PHOSPHATE ION Authors: Zhang, M, Zhang, Y. Deposit date: 2009-12-09 Release date: 2010-03-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci., 19, 2010
1UK1	Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor Descriptor: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1 Authors: Kinoshita, T. Deposit date: 2003-08-14 Release date: 2004-09-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase J.Med.Chem., 47, 2004
6HLW	Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of enterovirus-A71 (fusion protein) Descriptor: Genome polyprotein, Golgi resident protein GCP60 Authors: Klima, M, Boura, E. Deposit date: 2018-09-11 Release date: 2019-07-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.728 Å) Cite: Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathog., 15, 2019
6HLN	Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of enterovirus-D68 Descriptor: Genome polyprotein, Golgi resident protein GCP60 Authors: Klima, M, Boura, E. Deposit date: 2018-09-11 Release date: 2019-07-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathog., 15, 2019
8EFK	Structure of Lates calcarifer DNA polymerase theta polymerase domain with hairpin DNA Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(P*TP*TP*TP*TP*GP*GP*CP*TP*TP*TP*TP*GP*CP*CP*(2DA))-3'), Lates calcarifer DNA polymerase theta, ... Authors: Li, C, Zhu, H, Sun, J, Gao, Y. Deposit date: 2022-09-08 Release date: 2022-12-14 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
8EF9	Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*C)-3'), ... Authors: Li, C, Zhu, H, Sun, J, Gao, Y. Deposit date: 2022-09-08 Release date: 2022-12-14 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
8EFC	Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*CP*TP*GP*TP*GP*AP*GP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*CP*CP*TP*CP*AP*CP*AP*G)-3'), ... Authors: Li, C, Zhu, H, Sun, J, Gao, Y. Deposit date: 2022-09-08 Release date: 2022-12-14 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
1N48	Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion Descriptor: 5'-D(*CP*AP*(3DR)P*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Ling, H, Boudsocq, F, Woodgate, R, Yang, W. Deposit date: 2002-10-30 Release date: 2004-02-24 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A Y-family polymerase complexed with abasic lesions: catching DNA with a loaded nucleoside triphosphate To be Published
6HLT	Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of rhinovirus-14 (HRV14) Descriptor: Genome polyprotein, Golgi resident protein GCP60 Authors: Klima, M, Boura, E. Deposit date: 2018-09-11 Release date: 2019-07-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.815 Å) Cite: Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathog., 15, 2019
6HLV	Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of poliovirus-1 (L24A mutant) Descriptor: 3A protein, Golgi resident protein GCP60 Authors: Klima, M, Boura, E. Deposit date: 2018-09-11 Release date: 2019-07-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathog., 15, 2019
8B67	The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site Descriptor: ACETATE ION, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ... Authors: Parkash, V, Johansson, E. Deposit date: 2022-09-26 Release date: 2023-10-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B6K	The crystal structure of M644G variant of DNA Pol Epsilon containing dCTP in the polymerase active site Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... Authors: Parkash, V, Johansson, E. Deposit date: 2022-09-27 Release date: 2023-10-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B76	The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site Descriptor: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... Authors: Parkash, V, Johansson, E. Deposit date: 2022-09-28 Release date: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
6HM8	Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of enterovirus-D68 (fusion protein) Descriptor: Genome polyprotein, Golgi resident protein GCP60 Authors: Klima, M, Boura, E. Deposit date: 2018-09-12 Release date: 2019-07-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.277 Å) Cite: Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathog., 15, 2019
4O3N	Crystal structure of human dna polymerase eta in ternary complex with native dna and incoming nucleotide (dcp) Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2013-12-18 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.579 Å) Cite: Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4GXK	R283K DNA polymerase beta ternary complex with a templating 8OG and incoming dATP analog Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Freudenthal, B.D, Beard, W.A, Wilson, S.H. Deposit date: 2012-09-04 Release date: 2013-01-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.998 Å) Cite: DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion. Nucleic Acids Res., 41, 2013

<146147148149150151152153154155156157158159160161>