5SZK
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![BU of 5szk by Molmil](/molmil-images/mine/5szk) | Structure of human N-terminally engineered Rab1b in complex with the bMERB domain of Mical-cL | Descriptor: | MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Gazdag, E.M, Mueller, M.P. | Deposit date: | 2016-08-14 | Release date: | 2016-08-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. Elife, 5, 2016
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7Z7T
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![BU of 7z7t by Molmil](/molmil-images/mine/7z7t) | Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7Z83
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![BU of 7z83 by Molmil](/molmil-images/mine/7z83) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 8, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZC5
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![BU of 7zc5 by Molmil](/molmil-images/mine/7zc5) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 8, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-25 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7Z84
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![BU of 7z84 by Molmil](/molmil-images/mine/7z84) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 8, Open-ready state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7Z80
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![BU of 7z80 by Molmil](/molmil-images/mine/7z80) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 8, Closed state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7Z7S
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![BU of 7z7s by Molmil](/molmil-images/mine/7z7s) | Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Closed state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7Z7V
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![BU of 7z7v by Molmil](/molmil-images/mine/7z7v) | Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Open-ready state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7Z7R
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![BU of 7z7r by Molmil](/molmil-images/mine/7z7r) | Complex I from E. coli, LMNG-purified, Apo, Open-ready state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-16 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZCI
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![BU of 7zci by Molmil](/molmil-images/mine/7zci) | Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2022-03-28 | Release date: | 2022-09-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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8PTQ
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![BU of 8ptq by Molmil](/molmil-images/mine/8ptq) | COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5l | Descriptor: | 1,2-ETHANEDIOL, Monoglyceride lipase, methyl 4-[(2~{S},3~{R})-3-(4-fluorophenyl)-1-(1-methanoylpiperidin-4-yl)-4-oxidanylidene-azetidin-2-yl]benzoate | Authors: | Butini, S, Grether, U, Benz, J, Leibrock, L, Maramai, S, Papa, A, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. | Deposit date: | 2023-07-14 | Release date: | 2024-01-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
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8PTC
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![BU of 8ptc by Molmil](/molmil-images/mine/8ptc) | COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5d | Descriptor: | 1,2-ETHANEDIOL, 4-[(3~{R},4~{S})-2-oxidanylidene-3,4-diphenyl-azetidin-1-yl]piperidine-1-carbaldehyde, Monoglyceride lipase | Authors: | Butini, S, Benz, J, Grether, U, Leibrock, L, Papa, A, Maramai, S, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. | Deposit date: | 2023-07-14 | Release date: | 2024-01-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
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8PTR
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![BU of 8ptr by Molmil](/molmil-images/mine/8ptr) | COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5r | Descriptor: | (3~{R},4~{S})-4-(1,3-benzodioxol-5-yl)-1-[1-(benzotriazol-1-ylcarbonyl)piperidin-4-yl]-3-(3-fluorophenyl)azetidin-2-one, 1,2-ETHANEDIOL, Monoglyceride lipase | Authors: | Butini, S, Benz, J, Grether, U, Leibrock, L, Papa, A, Maramai, S, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. | Deposit date: | 2023-07-14 | Release date: | 2024-01-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
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4WNB
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![BU of 4wnb by Molmil](/molmil-images/mine/4wnb) | Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis bound to 3-OPC-CoA | Descriptor: | 3-oxo-4-pregnene-20-carboxyl-Coenzyme A, CADMIUM ION, CALCIUM ION, ... | Authors: | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | Deposit date: | 2014-10-11 | Release date: | 2014-10-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
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7YV3
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![BU of 7yv3 by Molmil](/molmil-images/mine/7yv3) | |
7QIA
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![BU of 7qia by Molmil](/molmil-images/mine/7qia) | Structure of apo-EleNRMT in complex with two nanobodies at 3.5A | Descriptor: | Divalent metal cation transporter, Nanobody 1, Nanobody 2 | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | Deposit date: | 2021-12-14 | Release date: | 2021-12-29 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family. Elife, 11, 2022
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7QIC
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![BU of 7qic by Molmil](/molmil-images/mine/7qic) | Structure of magnesium-bound EleNRMT in complex with two nanobodies at 4.1A | Descriptor: | Divalent metal cation transporter, MAGNESIUM ION, Nanobody 1, ... | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | Deposit date: | 2021-12-14 | Release date: | 2021-12-29 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family. Elife, 11, 2022
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4X28
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![BU of 4x28 by Molmil](/molmil-images/mine/4x28) | Crystal structure of the ChsE4-ChsE5 complex from Mycobacterium tuberculosis | Descriptor: | Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | Authors: | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | Deposit date: | 2014-11-26 | Release date: | 2015-02-18 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA. Acs Infect Dis., 1, 2015
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7RDX
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![BU of 7rdx by Molmil](/molmil-images/mine/7rdx) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - open class | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-11-24 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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7RDZ
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![BU of 7rdz by Molmil](/molmil-images/mine/7rdz) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - apo class | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-11-24 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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7RE3
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![BU of 7re3 by Molmil](/molmil-images/mine/7re3) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC dimer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-11-24 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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7RE1
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![BU of 7re1 by Molmil](/molmil-images/mine/7re1) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC (composite) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-12-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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7RE2
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![BU of 7re2 by Molmil](/molmil-images/mine/7re2) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(1)-RTC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-12-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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7RDY
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![BU of 7rdy by Molmil](/molmil-images/mine/7rdy) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - engaged class | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-12-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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7RE0
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![BU of 7re0 by Molmil](/molmil-images/mine/7re0) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - swiveled class | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Helicase, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2021-07-12 | Release date: | 2021-12-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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