PDB: 82686 resultsInfo pagesStatus searchChemie searchBIRD

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4QFH	Structure of a glucose-6-phosphate isomerase from Trypanosoma cruzi Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Glucose-6-phosphate isomerase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-05-21 Release date: 2014-06-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of a glucose-6-phosphate isomerase from Trypanosoma cruzi To be Published
4MUX	IspH in complex with pyridin-3-ylmethyl diphosphate Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, pyridin-3-ylmethyl trihydrogen diphosphate Authors: Span, I, Eisenreich, W, Bacher, A, Oldfield, E, Groll, M. Deposit date: 2013-09-23 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Insights into the Binding of Pyridines to the Iron-Sulfur Enzyme IspH. J.Am.Chem.Soc., 136, 2014
4P8R	Structure of a glycosomal glyceraldehyde 3-phosphate dehydrogenase from Trypanosoma brucei Descriptor: Glyceraldehyde 3-phosphate dehydrogenase, cytosolic, MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-03-31 Release date: 2014-06-18 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of a glycosomal glyceraldehyde 3-phosphate dehydrogenase from Trypanosoma brucei to be published
5N06	Crystal structure of Tie1 Fibronectin-like domain 3 Descriptor: Tyrosine-protein kinase receptor Tie-1 Authors: Leppanen, V.-M, Saharinen, P, Alitalo, K. Deposit date: 2017-02-02 Release date: 2017-04-26 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.501 Å) Cite: Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4L2L	Human Leukotriene A4 Hydrolase complexed with ligand 4-(4-benzylphenyl)thiazol-2-amine Descriptor: 4-(4-benzylphenyl)-1,3-thiazol-2-amine, ACETATE ION, Leukotriene A-4 hydrolase, ... Authors: Stsiapanava, A, Rinaldo-Matthis, A, Haeggstrom, J.Z. Deposit date: 2013-06-04 Release date: 2014-03-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.648 Å) Cite: Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. Proc.Natl.Acad.Sci.USA, 111, 2014
5Q1Y	PanDDA analysis group deposition -- Crystal Structure of DCLRE1A in complex with FMOPL000032a Descriptor: 2-[cyclohexyl(methylsulfonyl)amino]ethanamide, DNA cross-link repair 1A protein, MALONATE ION, ... Authors: Newman, J.A, Aitkenhead, H, Lee, S.Y, Kupinska, K, Burgess-Brown, N, Tallon, R, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2017-05-15 Release date: 2018-08-08 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.42 Å) Cite: PanDDA analysis group deposition To Be Published
3BNW	Crystal structure of riboflavin kinase from Trypanosoma brucei Descriptor: Riboflavin kinase, putative Authors: Merritt, E.A, Holmes, M, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2007-12-14 Release date: 2008-01-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Riboflavin kinase from Trypanosoma brucei. To be Published
5RJP	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00024672 Descriptor: 4-bromo-1-(2-hydroxyethyl)pyridin-2(1H)-one, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.242 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RK3	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1501469697 Descriptor: 3-amino-1,6-dimethylpyridin-2(1H)-one, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.31 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RKN	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z373768900 Descriptor: N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.23 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RJW	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z256709556 Descriptor: 3-methylthiophene-2-carboxylic acid, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.514 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RKB	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z2004563941 Descriptor: (1S)-1-(1-cyclopentyl-1H-pyrazol-4-yl)ethan-1-ol, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.279 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RKJ	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z373768898 Descriptor: N-(1-ethyl-1H-pyrazol-4-yl)cyclopentanecarboxamide, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.46 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RVX	PanDDA analysis group deposition -- Crystal Structure of DHTKD1 in complex with Z804566442 Descriptor: 5-ethyl-~{N}-[(1-methylpyrazol-4-yl)methyl]thiophene-2-carboxamide, MAGNESIUM ION, Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, ... Authors: Bezerra, G.A, Foster, W.R, Bailey, H.J, Shrestha, L, Krojer, T, Brandao-Neto, J, Douangamath, A, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Yue, W.W. Deposit date: 2020-10-27 Release date: 2020-11-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.661 Å) Cite: PanDDA analysis group deposition To Be Published
5RGY	PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z1535580916 (Mpro-x2581) Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, N-(4-methoxypyridin-2-yl)-2-(naphthalen-2-yl)acetamide Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-05-15 Release date: 2020-05-27 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.976 Å) Cite: PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen To Be Published
5RJR	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z45705015 Descriptor: PH-interacting protein, ~{N}-[2-(4-fluorophenyl)ethyl]methanesulfonamide Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.27 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RK7	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z31721097 Descriptor: PH-interacting protein, ethyl morpholine-4-carboxylate Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.304 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RKP	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1079512010 Descriptor: 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.35 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RVW	PanDDA analysis group deposition -- Crystal Structure of DHTKD1 in complex with Z1587220559 Descriptor: 2-{[(1H-benzimidazol-2-yl)amino]methyl}phenol, MAGNESIUM ION, Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, ... Authors: Bezerra, G.A, Foster, W.R, Bailey, H.J, Shrestha, L, Krojer, T, Brandao-Neto, J, Douangamath, A, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Yue, W.W. Deposit date: 2020-10-27 Release date: 2020-11-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.614 Å) Cite: PanDDA analysis group deposition To Be Published
5RGV	PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z4444622066 (Mpro-x2563) Descriptor: 2-(isoquinolin-4-yl)-N-phenylacetamide, 3C-like proteinase, DIMETHYL SULFOXIDE Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-05-15 Release date: 2020-05-27 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen To Be Published
5RJN	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00024673 Descriptor: 4-bromo-1-(2-methoxyethyl)-1H-pyrazole, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.435 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RK4	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z56791867 Descriptor: N,N-diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.284 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RKH	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z31432917 Descriptor: 2-(4-methylphenoxy)-1-(4-methylpiperazin-4-ium-1-yl)ethanone, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.252 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RKX	PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1324080698 Descriptor: 3-fluoro-5-methylbenzene-1-sulfonamide, PH-interacting protein Authors: Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. Deposit date: 2020-06-02 Release date: 2020-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.24 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5RH8	PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z4444621965 (Mpro-x2764) Descriptor: 2-(cyanomethoxy)-N-[(1,2-thiazol-4-yl)methyl]benzamide, 3C-like proteinase, DIMETHYL SULFOXIDE Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-05-15 Release date: 2020-05-27 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.81 Å) Cite: PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen To Be Published

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