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9B61
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BU of 9b61 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH5, consensus structure of LBD-TMD-TARPgamma2
Descriptor: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T, Greger, I.H.
Deposit date:2024-03-23
Release date:2024-07-31
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
4U5G
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BU of 4u5g by Molmil
Crystal structure of con-ikot-ikot toxin
Descriptor: Con-ikot-ikot, ZINC ION
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1997 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5H
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BU of 4u5h by Molmil
crystal structure of con-ikot-ikot toxin
Descriptor: Con-ikot-ikot
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
6I7G
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BU of 6i7g by Molmil
Crystal structure of dimeric wild type FICD complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, DI(HYDROXYETHYL)ETHER, ...
Authors:Perera, L.A, Yan, Y, Read, R.J, Ron, D.
Deposit date:2018-11-16
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
1L0G
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BU of 1l0g by Molmil
X-ray Crystal Structure of AmpC S64G Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1LL5
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BU of 1ll5 by Molmil
X-ray crystal structure of AmpC WT beta-lactamase in complex with covalently bound imipenem
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-04-26
Release date:2002-11-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Imipenem Inhibition of Class C beta-lactamases
ANTIMICROB.AGENTS CHEMOTHER., 46, 2002
6I7J
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BU of 6i7j by Molmil
Crystal structure of monomeric FICD mutant L258D
Descriptor: Adenosine monophosphate-protein transferase FICD, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ...
Authors:Perera, L.A, Yan, Y, Read, R.J, Ron, D.
Deposit date:2018-11-16
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I7K
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BU of 6i7k by Molmil
Crystal structure of monomeric FICD mutant L258D complexed with MgATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, ETHANOL, ...
Authors:Perera, L.A, Yan, Y, Read, R.J, Ron, D.
Deposit date:2018-11-16
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I7H
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BU of 6i7h by Molmil
Crystal structure of dimeric FICD mutant K256S
Descriptor: Adenosine monophosphate-protein transferase FICD, MAGNESIUM ION
Authors:Perera, L.A, Yan, Y, Read, R.J, Ron, D.
Deposit date:2018-11-16
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I7I
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BU of 6i7i by Molmil
Crystal structure of dimeric FICD mutant K256A complexed with MgATP
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, ...
Authors:Perera, L.A, Yan, Y, Read, R.J, Ron, D.
Deposit date:2018-11-16
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
3SOG
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BU of 3sog by Molmil
Crystal structure of the BAR domain of human Amphiphysin, isoform 1
Descriptor: 1,2-ETHANEDIOL, Amphiphysin, POTASSIUM ION
Authors:Allerston, C.K, Krojer, T, Chaikuad, A, Cooper, C.D.O, Berridge, G, Savitsky, P, Vollmar, M, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC)
Deposit date:2011-06-30
Release date:2011-07-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:

4U5C
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BU of 4u5c by Molmil
Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist FW and postitive modulator (R,R)-2b complex
Descriptor: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.6883 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5E
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BU of 4u5e by Molmil
Crystal structure of GluA2 T625G, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.5073 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5B
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BU of 4u5b by Molmil
Crystal structure of GluA2 A622T, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.5037 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5F
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BU of 4u5f by Molmil
Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex, GluA2cryst2 construct
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-24
Release date:2014-08-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
6JRQ
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BU of 6jrq by Molmil
Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus
Descriptor: 1,2-ETHANEDIOL, Adenylosuccinate synthetase, INOSINIC ACID
Authors:Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2019-04-05
Release date:2020-04-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus HB8
To Be Published
8XEP
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BU of 8xep by Molmil
Crystal structure of a Legionella pneumophila type IV effector in complex with ubiquitin
Descriptor: SULFATE ION, Type IV effector MavL, Ubiquitin
Authors:Tan, J.X, Wang, X.F, Zhou, Y, Zhu, Y.Q.
Deposit date:2023-12-12
Release date:2024-05-01
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Legionella effector LnaB is a phosphoryl AMPylase that impairs phosphosignalling.
Nature, 631, 2024
7OCA
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BU of 7oca by Molmil
Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
6QKZ
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BU of 6qkz by Molmil
Full length GluA1/2-gamma8 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, ...
Authors:Herguedas, B, Garcia-Nafria, J, Greger, I.G.
Deposit date:2019-01-30
Release date:2019-03-27
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
6QKC
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BU of 6qkc by Molmil
GluA1/2 In complex with auxiliary subunit gamma-8
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 1, ...
Authors:Herguedas, B, Garcia-Nafria, J, Greger, I.G.
Deposit date:2019-01-28
Release date:2019-03-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
7OCC
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BU of 7occ by Molmil
NTD of resting state GluA1/A2 heterotertramer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 1, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCD
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BU of 7ocd by Molmil
Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
2AYI
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BU of 2ayi by Molmil
Wild-type AmpT from Thermus thermophilus
Descriptor: Aminopeptidase T, ZINC ION
Authors:Odintsov, S.G, Sabala, I, Bourenkov, G, Rybin, V, Bochtler, M.
Deposit date:2005-09-07
Release date:2005-11-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Substrate Access to the Active Sites in Aminopeptidase T, a Representative of a New Metallopeptidase Clan.
J.Mol.Biol., 354, 2005
7QHB
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BU of 7qhb by Molmil
Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ...
Authors:Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H.
Deposit date:2021-12-11
Release date:2022-02-23
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
7OOD
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BU of 7ood by Molmil
Mycoplasma pneumoniae 50S subunit of ribosomes in chloramphenicol-treated cells
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-05-27
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022

238582

數據於2025-07-09公開中

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