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3T3N
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Molecular basis for the recognition and cleavage of RNA (UUCCGU) by the bifunctional 5'-3' exo/endoribonuclease RNase J
Descriptor: Metal dependent hydrolase, O2'methyl-RNA, ZINC ION
Authors:Dorleans, A, Li de la Sierra-Gallay, I, Piton, J, Zig, L, Gilet, L, Putzer, H, Condon, C.
Deposit date:2011-07-25
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Molecular Basis for the Recognition and Cleavage of RNA by the Bifunctional 5'-3' Exo/Endoribonuclease RNase J.
Structure, 19, 2011
8I2J
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E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1-(4-methoxyphenyl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I27
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E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, 4-methoxybenzenecarbonitrile, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2M
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The crystal structure of homodimeric E. coli tryptophanyl-tRNA synthetase bound with niraparib at one of its two active sites
Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2A
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BU of 8i2a by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, 5-METHOXYBENZIMIDAZOLE, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2C
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E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, 4-methoxyaniline, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2L
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E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, CHLORZOXAZONE, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I1Z
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BU of 8i1z by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment
Descriptor: 1-(2,3-dihydro-1-benzofuran-5-yl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-13
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
6BJH
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BU of 6bjh by Molmil
CIRV p19 mutant T111S in complex with siRNA
Descriptor: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
Authors:Foss, D.V, Schirle, N.T, MacRae, I.J, Pezacki, J.P.
Deposit date:2017-11-06
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
5U36
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BU of 5u36 by Molmil
Crystal Structure Of A Mutant M. Jannashii Tyrosyl-tRNA Synthetase
Descriptor: Tyrosine--tRNA ligase
Authors:Luo, X, Fu, G, Zhu, X, Wilson, I.A, Wang, F.
Deposit date:2016-12-01
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria.
Nat. Chem. Biol., 13, 2017
6NY2
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BU of 6ny2 by Molmil
CasX-gRNA-DNA(45bp) state I
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
6KOR
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Crystal structure of the RRM domain of SYNCRIP
Descriptor: Heterogeneous nuclear ribonucleoprotein Q
Authors:Chen, Y, Chan, J, Chen, W, Jobichen, C.
Deposit date:2019-08-12
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:SYNCRIP, a new player in pri-let-7a processing.
Rna, 26, 2020
6NY1
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BU of 6ny1 by Molmil
CasX-gRNA-DNA(30bp) State II
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
8HKE
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BU of 8hke by Molmil
dsRNA transporter
Descriptor: RNA (37-MER), Systemic RNA interference defective protein 1, ZINC ION
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-25
Release date:2023-11-29
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 31, 2024
5I9D
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BU of 5i9d by Molmil
Crystal structure of designed pentatricopeptide repeat protein dPPR-U8A2 in complex with its target RNA U8A2
Descriptor: RNA (5'-R(*GP*GP*GP*G*UP*UP*UP*UP*AP*AP*UP*UP*UP*UP*CP*CP*CP*C)-3'), pentatricopeptide repeat protein dPPR-U8A2
Authors:Shen, C, Zhang, D, Guan, Z, Zou, T, Yin, P.
Deposit date:2016-02-20
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins.
Nat Commun, 7, 2016
5I9H
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BU of 5i9h by Molmil
Crystal structure of designed pentatricopeptide repeat protein dPPR-U8G2 in complex with its target RNA U8G2
Descriptor: RNA (5'-R(*GP*GP*GP*GP*UP*UP*UP*UP*GP*GP*UP*UP*UP*UP*CP*CP*CP*C)-3'), pentatricopeptide repeat protein dPPR-U8G2
Authors:Shen, C, Zhang, D, Guan, Z, Zou, T, Yin, P.
Deposit date:2016-02-20
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins.
Nat Commun, 7, 2016
5I9G
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BU of 5i9g by Molmil
Crystal structure of designed pentatricopeptide repeat protein dPPR-U8C2 in complex with its target RNA U8C2
Descriptor: RNA (5'-R(*GP*GP*G*GP*UP*UP*UP*UP*CP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'), pentatricopeptide repeat protein dPPR-U8C2
Authors:Shen, C, Zhang, D, Guan, Z, Zou, T, Yin, P.
Deposit date:2016-02-20
Release date:2016-04-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.288 Å)
Cite:Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins.
Nat Commun, 7, 2016
8H99
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BU of 8h99 by Molmil
Crystal structure of E. coli ThrS catalytic domain mutant
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, IMIDAZOLE, MAGNESIUM ION, ...
Authors:Qiao, H, Xia, M, Wang, J, Fang, P.
Deposit date:2022-10-25
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
8H9C
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BU of 8h9c by Molmil
Crystal structure of chemically modified E. coli ThrS catalytic domain 4
Descriptor: N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION
Authors:Qiao, H, Xia, M, Wang, J, Fang, P.
Deposit date:2022-10-25
Release date:2023-02-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
8H9B
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BU of 8h9b by Molmil
Crystal structure of chemically modified E. coli ThrS catalytic domain 3
Descriptor: N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION
Authors:Qiao, H, Xia, M, Wang, J, Fang, P.
Deposit date:2022-10-25
Release date:2023-02-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
8H9A
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BU of 8h9a by Molmil
Crystal structure of chemically modified E. coli ThrS catalytic domain 2
Descriptor: N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION
Authors:Qiao, H, Xia, M, Wang, J, Fang, P.
Deposit date:2022-10-25
Release date:2023-02-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
5I9F
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BU of 5i9f by Molmil
Crystal structure of designed pentatricopeptide repeat protein dPPR-U10 in complex with its target RNA U10
Descriptor: RNA (5'-R(*GP*GP*GP*GP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*CP*CP*CP*C)-3'), pentatricopeptide repeat protein dPPR-U10
Authors:Shen, C, Zhang, D, Guan, Z, Zou, T, Yin, Y.
Deposit date:2016-02-20
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins.
Nat Commun, 7, 2016
4AYB
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BU of 4ayb by Molmil
RNAP at 3.2Ang
Descriptor: DNA-DIRECTED RNA POLYMERASE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
Authors:Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A.
Deposit date:2012-06-19
Release date:2012-08-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA.
Nucleic Acids Res., 40, 2012
6THN
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BU of 6thn by Molmil
Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E symmetry expansion+2fold focused classification
Descriptor: Genome polyprotein, MYRISTIC ACID, RNA Peak 9 Bernoulli Plot, ...
Authors:Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G.
Deposit date:2019-11-20
Release date:2020-12-09
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Plos Pathog., 16, 2020
8S6W
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BU of 8s6w by Molmil
Small circular RNA dimer - Class 3
Descriptor: RNA (36-MER)
Authors:McRae, E.K, Kristoffersen, E.L, Holliger, P, Andersen, E.S.
Deposit date:2024-02-28
Release date:2025-01-29
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis.
Nucleic Acids Res., 53, 2025

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數據於2025-07-23公開中

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