6OVC
| hMcl1 inhibitor complex | Descriptor: | (2S)-N-(benzylsulfonyl)-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Poppe, L. | Deposit date: | 2019-05-07 | Release date: | 2019-05-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies. Cancer Discov, 8, 2018
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2MHS
| NMR Structure of human Mcl-1 | Descriptor: | Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Liu, G, Poppe, L, Aoki, K, Yamane, H, Lewis, J, Szyperski, T. | Deposit date: | 2013-12-04 | Release date: | 2014-05-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-Quality NMR Structure of Human Anti-Apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design. Plos One, 9, 2014
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2KBW
| Solution Structure of human Mcl-1 complexed with human Bid_BH3 peptide | Descriptor: | BH3-interacting domain death agonist, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Liu, Q, Moldoveanu, T, Sprules, T, Matta-Camacho, E, Mansur-Azzam, N, Gehring, K. | Deposit date: | 2008-12-09 | Release date: | 2009-12-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Apoptotic regulation by MCL-1 through heterodimerization. J.Biol.Chem., 285, 2010
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