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PDB: 52 results
5F20
Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
Descriptor:
3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
Authors:
Skene, R.J.
Deposit date:
2015-12-01
Release date:
2016-01-13
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.91 Å)
Cite:
Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors.
J.Med.Chem., 59, 2016
8EYC
Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with TYK2 activation loop phosphopeptide
Descriptor:
Non-receptor tyrosine-protein kinase TYK2 activation loop phosphopeptide, Tyrosine-protein phosphatase non-receptor type 1
Authors:
Morris, R
,
Kershaw, N.J
,
Babon, J.J.
Deposit date:
2022-10-26
Release date:
2023-08-16
Last modified:
2023-11-15
Method:
X-RAY DIFFRACTION (2.99 Å)
Cite:
Structure guided studies of the interaction between PTP1B and JAK.
Commun Biol, 6, 2023
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數據於2024-07-31公開中