6DYF
| Cu(II)-bound structure of the engineered cyt cb562 variant, CH3Y | Descriptor: | CHLORIDE ION, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Tezcan, F.A, Rittle, J. | Deposit date: | 2018-07-01 | Release date: | 2019-04-24 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | An efficient, step-economical strategy for the design of functional metalloproteins. Nat.Chem., 11, 2019
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5YO6
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4JEA
| Crystal structure of an engineered Zn-RIDC1 construct with four interfacial disulfide bonds | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ZINC ION, ... | Authors: | Tezcan, F.A, Medina-Morales, A.M, Perez, A, Brodin, J.D. | Deposit date: | 2013-02-26 | Release date: | 2013-08-21 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | In Vitro and Cellular Self-Assembly of a Zn-Binding Protein Cryptand via Templated Disulfide Bonds. J.Am.Chem.Soc., 135, 2013
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7LSJ
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7MK4
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6DYC
| Co(II)-bound structure of the engineered cyt cb562 variant, CH3 | Descriptor: | CALCIUM ION, COBALT (II) ION, HEME C, ... | Authors: | Tezcan, F.A, Rittle, J. | Deposit date: | 2018-07-01 | Release date: | 2019-04-24 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | An efficient, step-economical strategy for the design of functional metalloproteins. Nat.Chem., 11, 2019
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5YO4
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7LRV
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6OT4
| Bimetallic dodecameric cage design 2 (BMC2) from cytochrome cb562 | Descriptor: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | Authors: | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | Deposit date: | 2019-05-02 | Release date: | 2020-01-29 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Constructing protein polyhedra via orthogonal chemical interactions. Nature, 578, 2020
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256B
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6DYG
| Fe(II)-bound structure of the engineered cyt cb562 variant, CH3Y | Descriptor: | FE (III) ION, HEME C, MAGNESIUM ION, ... | Authors: | Tezcan, F.A, Rittle, J. | Deposit date: | 2018-07-01 | Release date: | 2019-04-24 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | An efficient, step-economical strategy for the design of functional metalloproteins. Nat.Chem., 11, 2019
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6OT8
| Bimetallic hexameric cage design 4 (BMC4) from cytochrome cb562 | Descriptor: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | Authors: | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | Deposit date: | 2019-05-02 | Release date: | 2020-01-29 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Constructing protein polyhedra via orthogonal chemical interactions. Nature, 578, 2020
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7LSN
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8DRM
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5YM7
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7RWX
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7LSL
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8DRL
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8DEN
| Heme-Free Cytochrome Variant ApoCyt | Descriptor: | Soluble cytochrome b562 | Authors: | Hoffnagle, A.H, Eng, V.H, Tezcan, F.A. | Deposit date: | 2022-06-20 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Computationally Guided Redesign of a Heme-free Cytochrome with Native-like Structure and Stability. Biochemistry, 61, 2022
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6DYL
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6WZ0
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7LR5
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7LRA
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8DRF
| Zn(II)-bound B2 dimer (H60/H100/H104) | Descriptor: | HEME C, Soluble cytochrome b562, ZINC ION | Authors: | Choi, T.S, Tezcan, F.A. | Deposit date: | 2022-07-20 | Release date: | 2022-10-12 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Design of a Flexible, Zn-Selective Protein Scaffold that Displays Anti-Irving-Williams Behavior. J.Am.Chem.Soc., 144, 2022
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7RWW
| Crystal structure of a Zn-bound RIDC1 variant | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Kakkis, A, Golub, E. | Deposit date: | 2021-08-20 | Release date: | 2022-06-29 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Redox- and metal-directed structural diversification in designed metalloprotein assemblies. Chem.Commun.(Camb.), 58, 2022
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