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PDB: 2 results
8FD9
Structure of BTK kinase domain with the second-generation inhibitor acalabrutinib
Descriptor:
4-[(4S)-8-amino-3-{(2S)-1-[(2E)-but-2-enoyl]pyrrolidin-2-yl}imidazo[1,5-a]pyrazin-1-yl]-N-(pyridin-2-yl)benzamide, BROMIDE ION, Tyrosine-protein kinase BTK
Authors:
Lin, D.Y
,
Andreotti, A.H.
Deposit date:
2022-12-02
Release date:
2023-07-05
Last modified:
2023-09-13
Method:
X-RAY DIFFRACTION (1.7 Å)
Cite:
Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.
Plos One, 18, 2023
8FF0
Structure of BTK kinase domain with the second-generation inhibitor tirabrutinib
Descriptor:
6-azanyl-9-[(3~{R})-1-[(~{E})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one, Tyrosine-protein kinase BTK
Authors:
Lin, D.Y
,
Andreotti, A.H.
Deposit date:
2022-12-07
Release date:
2023-07-05
Last modified:
2023-09-13
Method:
X-RAY DIFFRACTION (2.6 Å)
Cite:
Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.
Plos One, 18, 2023
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數據於2024-10-30公開中