8S5A
 
 | | The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA | | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*CP*A)-3'), ... | | Authors: | Aretz, J, Jeyasankar, G, Salerno-Kochan, A, Thomsen, M, Thieulin-Pardo, G, Haque, T, Monteagudo, E, Felsenfeld, D, Finley, M, Vogt, T.F, Boudet, J, Prasad, B.C. | | Deposit date: | 2024-02-23 | | Release date: | 2025-03-05 | | Last modified: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2.645 Å) | | Cite: | A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA.
Nat Commun, 16, 2025
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9GY0
 | | Cryo_EM structure of human FAN1 R507H mutant in complex with 5' flap DNA substrate and PCNA | | Descriptor: | CALCIUM ION, DNA (Continuous), DNA (Post-Nick), ... | | Authors: | Jeyasankar, G, Salerno-Kochan, A, Thomsen, M. | | Deposit date: | 2024-10-01 | | Release date: | 2025-01-29 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA.
Nat Commun, 16, 2025
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9EO1
 | | Cryo_EM structure of human FAN1 in complex with 5' flap DNA substrate | | Descriptor: | DNA (continuous), DNA (post-nick), DNA (pre-nick), ... | | Authors: | Jeyasankar, G, Salerno-Kochan, A, Thomsen, M. | | Deposit date: | 2024-03-14 | | Release date: | 2025-01-29 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA.
Nat Commun, 16, 2025
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9EOA
 | | Cryo_EM structure of human FAN1 in complex with 5' flap DNA substrate and PCNA | | Descriptor: | DNA (continuous), DNA (post-nick), DNA (pre-nick), ... | | Authors: | Jeyasankar, G, Salerno-Kochan, A, Thomsen, M. | | Deposit date: | 2024-03-14 | | Release date: | 2025-01-29 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA.
Nat Commun, 16, 2025
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