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PDB: 8 results
8FKF
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR36706
Descriptor:
1,2-ETHANEDIOL, 2-chloro-N-(5-fluoropyridin-3-yl)-5-nitrobenzamide, GLYCEROL, ...
Authors:
MacTavish, B.S
,
Kojetin, D.J.
Deposit date:
2022-12-21
Release date:
2024-04-17
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (1.82 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FKD
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33068
Descriptor:
1,2-ETHANEDIOL, 2-chloro-N-(6-cyanopyridin-3-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ...
Authors:
MacTavish, B.S
,
Kojetin, D.J.
Deposit date:
2022-12-21
Release date:
2024-04-17
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (2.22 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FKG
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33486
Descriptor:
1,2-ETHANEDIOL, 2-chloro-N-(5-cyanopyridin-2-yl)-5-nitrobenzamide, GLYCEROL, ...
Authors:
MacTavish, B.S
,
Kojetin, D.J.
Deposit date:
2022-12-21
Release date:
2024-04-17
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (2.12 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FKC
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33544
Descriptor:
1,2-ETHANEDIOL, 2-chloro-N-(5-cyanopyridin-3-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ...
Authors:
MacTavish, B.S
,
Kojetin, D.J.
Deposit date:
2022-12-21
Release date:
2024-04-17
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (1.42 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FHE
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662
Descriptor:
2-chloro-5-nitro-N-phenylbenzamide, Nuclear receptor corepressor 1, Peroxisome proliferator-activated receptor gamma
Authors:
Shang, J
,
Kojetin, D.J.
Deposit date:
2022-12-14
Release date:
2024-03-20
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FHG
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and ZINC5672437
Descriptor:
N-(4-carbamoylphenyl)-2-chloro-5-nitrobenzamide, Nuclear receptor corepressor 1, Peroxisome proliferator-activated receptor gamma
Authors:
Shang, J
,
Kojetin, D.J.
Deposit date:
2022-12-14
Release date:
2024-03-20
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FHF
Crystal structure of PPARgamma ligand-binding domain in complex with ZINC5672437
Descriptor:
N-(4-carbamoylphenyl)-2-chloro-5-nitrobenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:
Shang, J
,
Kojetin, D.J.
Deposit date:
2022-12-14
Release date:
2024-03-20
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (2.1 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
8FKE
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR32904
Descriptor:
1,2-ETHANEDIOL, 2-chloro-N-(2-methylpyridin-4-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ...
Authors:
MacTavish, B.S
,
Kojetin, D.J.
Deposit date:
2022-12-21
Release date:
2024-04-17
Last modified:
2025-04-30
Method:
X-RAY DIFFRACTION (2.02 Å)
Cite:
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Nat Commun, 16, 2025
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238582
數據於2025-07-09公開中