5KKR
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![BU of 5kkr by Molmil](/molmil-images/mine/5kkr) | KSR2:MEK1 Complex Bound to the Small Molecule APS-2-79 | Descriptor: | 6,7-dimethoxy-~{N}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amine, Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2 | Authors: | Dhawan, N.S, Scopton, A.P, Dar, A.C. | Deposit date: | 2016-06-22 | Release date: | 2016-08-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.509 Å) | Cite: | Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling. Nature, 537, 2016
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