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PDB: 2 results

4TN2
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BU of 4tn2 by Molmil
NS5b in complex with lactam-thiophene carboxylic acids
Descriptor: 3-[(2R)-2-cyclohexyl-5-oxopyrrolidin-1-yl]-5-phenylthiophene-2-carboxylic acid, Genome polyprotein
Authors:Chopra, R.
Deposit date:2014-06-02
Release date:2014-09-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
4TLR
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BU of 4tlr by Molmil
NS5b in complex with lactam-thiophene carboxylic acids
Descriptor: 3-{(2R,5R)-5-cyclohexyl-2-[(2R)-2-hydroxypropyl]-3-oxomorpholin-4-yl}-5-(3,3-dimethylbut-1-yn-1-yl)thiophene-2-carboxylic acid, 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, NS5b
Authors:Chopra, R.
Deposit date:2014-05-30
Release date:2014-12-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014

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數據於2024-07-10公開中

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