8UR1
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8U91
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8U92
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8U90
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8U8W
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8U93
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8GEK
| Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase | Authors: | Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | Deposit date: | 2023-03-06 | Release date: | 2024-03-20 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum To Be Published
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8DO5
| Crystal structure of NahE in complex with intermediate (R)-4-hydroxy-4-(2-hydroxyphenyl)-2-iminobutanoate | Descriptor: | (4R)-4-hydroxy-4-(2-hydroxyphenyl)butanoic acid, DIMETHYL SULFOXIDE, Trans-ohydrobenzylidenepyruvate hydratase aldolase | Authors: | LeVieux, J.A, Hardtke, H.A, Zhang, Y.J. | Deposit date: | 2022-07-12 | Release date: | 2022-12-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway. Arch.Biochem.Biophys., 733, 2023
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7MJF
| Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site | Descriptor: | (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase | Authors: | Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | Deposit date: | 2021-04-20 | Release date: | 2021-07-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site To Be Published
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7MDS
| Crystal structure of AtDHDPS1 in complex with MBDTA-2 | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ... | Authors: | Hall, C.J, Soares da Costa, T.P, Panjikar, S. | Deposit date: | 2021-04-06 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants. Elife, 10, 2021
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7M06
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with R,R-bislysine bound at the allosteric site at 2.7 Angstrom | Descriptor: | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... | Authors: | Saran, S, Sanders, D.A.R. | Deposit date: | 2021-03-10 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS To Be Published
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7LVL
| Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE | Authors: | Gilkes, J.M, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J.D. | Deposit date: | 2021-02-25 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum To Be Published
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7LOY
| Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase | Authors: | Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | Deposit date: | 2021-02-11 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum To Be Published
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7LCF
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7LBD
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group | Descriptor: | 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... | Authors: | Saran, S, Yazdi, M.M, Sanders, D.A.R. | Deposit date: | 2021-01-07 | Release date: | 2022-01-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Reversing the roles of a crucial hydrogen-bonding pair: a lysine-insensitive mutant of Campylobacter jejuni dihydrodipicolinate synthase, H59K, binds histidine in its allosteric site To Be Published
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7L4B
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7KZ2
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7KXG
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7KXH
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site in C2221 space group | Descriptor: | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... | Authors: | Saran, S, Sanders, D.A.R. | Deposit date: | 2020-12-03 | Release date: | 2021-12-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS. To Be Published
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7KX1
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7KWN
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7KWP
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7KWF
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site | Descriptor: | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... | Authors: | Saran, S, Sanders, D.A.R. | Deposit date: | 2020-11-30 | Release date: | 2021-12-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | ALLOSTERIC SITE RESIDUE 'H56' CAPS THE INHIBITOR AT THE TIGHT DIMER INTERFACE FOR TRANSMITTING THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS To Be Published
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7KUZ
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7KU6
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