6B58
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![BU of 6b58 by Molmil](/molmil-images/mine/6b58) | FrdA-SdhE assembly intermediate | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sharma, P, Iverson, T.M. | Deposit date: | 2017-09-28 | Release date: | 2018-01-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Crystal structure of an assembly intermediate of respiratory Complex II. Nat Commun, 9, 2018
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4MK1
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![BU of 4mk1 by Molmil](/molmil-images/mine/4mk1) | 5-bromopyridine-2,3-diol bound to influenza 2009 pH1N1 endonuclease | Descriptor: | 1,2-ETHANEDIOL, 5-bromo-3-hydroxypyridin-2(1H)-one, MANGANESE (II) ION, ... | Authors: | Bauman, J.D, Patel, D, Das, K, Arnold, E. | Deposit date: | 2013-09-04 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
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3LGH
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![BU of 3lgh by Molmil](/molmil-images/mine/3lgh) | |
1H8Y
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![BU of 1h8y by Molmil](/molmil-images/mine/1h8y) | Crystal structure of the class D beta-lactamase OXA-13 in complex with meropenem | Descriptor: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, BETA-LACTAMASE, SULFATE ION | Authors: | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | Deposit date: | 2001-02-17 | Release date: | 2001-07-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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1E5H
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![BU of 1e5h by Molmil](/molmil-images/mine/1e5h) | DELTA-R307A DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH SUCCINATE AND CARBON DIOXIDE | Descriptor: | CARBON DIOXIDE, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, ... | Authors: | Lee, H.J, Lloyd, M.D, Harlos, K, Clifton, I.J, Baldwin, J.E, Schofield, C.J. | Deposit date: | 2000-07-26 | Release date: | 2001-07-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs) J.Mol.Biol., 308, 2001
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1YMH
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![BU of 1ymh by Molmil](/molmil-images/mine/1ymh) | anti-HCV Fab 19D9D6 complexed with protein L (PpL) mutant A66W | Descriptor: | Fab 16D9D6, heavy chain, light chain, ... | Authors: | Granata, V, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A. | Deposit date: | 2005-01-21 | Release date: | 2005-05-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Comparison of the crystallization and crystal packing of two Fab single-site mutant protein L complexes. Acta Crystallogr.,Sect.D, 61, 2005
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5WCQ
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![BU of 5wcq by Molmil](/molmil-images/mine/5wcq) | Phosphotriesterase variant S2 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | Authors: | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | Deposit date: | 2017-07-01 | Release date: | 2018-07-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.576 Å) | Cite: | Phosphotriesterase variant S2 To Be Published
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1HHS
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![BU of 1hhs by Molmil](/molmil-images/mine/1hhs) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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2J3E
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![BU of 2j3e by Molmil](/molmil-images/mine/2j3e) | Dimerization is important for the GTPase activity of chloroplast translocon components atToc33 and psToc159 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, T7I23.11 PROTEIN | Authors: | Yeh, Y.-H, Kesavulu, M.M, Wu, S.-Z, Li, H.-M, Sun, Y.-J, Konozy, E.H, Hsiao, C.-D. | Deposit date: | 2006-08-21 | Release date: | 2007-03-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Dimerization is Important for the Gtpase Activity of Chloroplast Translocon Components Attoc33 and Pstoc159. J.Biol.Chem., 282, 2007
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5OGB
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![BU of 5ogb by Molmil](/molmil-images/mine/5ogb) | Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360. | Descriptor: | 4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 | Authors: | Chisholm, D, Tomlinson, C, Whiting, A, Pohl, E. | Deposit date: | 2017-07-12 | Release date: | 2018-10-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. Acs Chem.Biol., 14, 2019
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1PFQ
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![BU of 1pfq by Molmil](/molmil-images/mine/1pfq) | crystal structure of human apo dipeptidyl peptidase IV / CD26 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase IV soluble form | Authors: | Oefner, C, D'Arcy, A, Mac Sweeney, A, Pierau, S, Gardiner, R, Dale, G.E. | Deposit date: | 2003-05-27 | Release date: | 2003-07-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrolidine. Acta Crystallogr.,Sect.D, 59, 2003
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1H7H
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2J5R
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![BU of 2j5r by Molmil](/molmil-images/mine/2j5r) | 2.25 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after second radiation burn (radiation damage series) | Descriptor: | CHLORIDE ION, MALATE DEHYDROGENASE | Authors: | Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M. | Deposit date: | 2006-09-19 | Release date: | 2006-09-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment. J.Synchrotron Radiat., 14, 2007
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1H7F
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5WMB
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![BU of 5wmb by Molmil](/molmil-images/mine/5wmb) | Structure of the 10S (-)-cis-BP-dG modified Rev1 ternary complex (the BP residue is disordered) | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Rechkoblit, O, Kolbanovsky, A, Landes, H, Geacintov, N.E, Aggarwal, A.K. | Deposit date: | 2017-07-28 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase. Nat Commun, 8, 2017
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6AOM
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![BU of 6aom by Molmil](/molmil-images/mine/6aom) | Structure of molecular chaperone Grp94 bound to selective inhibitor methyl 2-[2-(2-benzylphenyl)ethyl]-3-chloro-4,6-dihydroxybenzoate | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, DI(HYDROXYETHYL)ETHER, Endoplasmin, ... | Authors: | Lieberman, R.L, Huard, D.J.E. | Deposit date: | 2017-08-16 | Release date: | 2017-10-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer. Chemistry, 23, 2017
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2XX3
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![BU of 2xx3 by Molmil](/molmil-images/mine/2xx3) | |
2J5Q
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![BU of 2j5q by Molmil](/molmil-images/mine/2j5q) | 2.15 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after first radiation burn (radiation damage series) | Descriptor: | CHLORIDE ION, MALATE DEHYDROGENASE | Authors: | Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M. | Deposit date: | 2006-09-19 | Release date: | 2006-09-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment. J.Synchrotron Radiat., 14, 2007
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1YQF
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1PGL
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![BU of 1pgl by Molmil](/molmil-images/mine/1pgl) | BEAN POD MOTTLE VIRUS (BPMV), MIDDLE COMPONENT | Descriptor: | 5'-R(*AP*GP*UP*CP*UP*C)-3', BEAN POD MOTTLE VIRUS LARGE (L) SUBUNIT, BEAN POD MOTTLE VIRUS SMALL (S) SUBUNIT | Authors: | Lin, T, Cavarelli, J, Johnson, J.E. | Deposit date: | 2003-05-28 | Release date: | 2003-11-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus. Virology, 314, 2003
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2IWQ
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![BU of 2iwq by Molmil](/molmil-images/mine/2iwq) | 7th PDZ domain of Multiple PDZ Domain Protein MPDZ | Descriptor: | MULTIPLE PDZ DOMAIN PROTEIN | Authors: | Elkins, J.M, Berridge, G, Savitsky, P, Smee, C.E.A, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A. | Deposit date: | 2006-07-03 | Release date: | 2006-07-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions. Protein Sci., 16, 2007
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6AVE
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![BU of 6ave by Molmil](/molmil-images/mine/6ave) | |
1PB3
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![BU of 1pb3 by Molmil](/molmil-images/mine/1pb3) | |
1PB1
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9CYO
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![BU of 9cyo by Molmil](/molmil-images/mine/9cyo) | Crystal structure of wild-type human PTP1B (PTPN1) at room temperature (298 K) | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy Biorxiv, 2024
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