364D
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![BU of 364d by Molmil](/molmil-images/mine/364d) | 3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*CP*CP*CP*AP*UP*GP*CP*GP*AP*GP*AP*GP*UP*AP*GP*G P*GP*AP*AP*CP*UP*GP*CP*CP*AP*GP*GP*CP*AP*U)-3'), RNA (5'-R(*CP*CP*GP*AP*UP*GP*GP*UP*AP*GP*UP*GP*UP*GP*GP*GP*G *UP*C)-3'), ... | Authors: | Correll, C.C, Freeborn, B, Moore, P.B, Steitz, T.A. | Deposit date: | 1997-12-08 | Release date: | 1998-01-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain. Cell(Cambridge,Mass.), 91, 1997
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4B7R
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![BU of 4b7r by Molmil](/molmil-images/mine/4b7r) | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | Deposit date: | 2012-08-21 | Release date: | 2012-10-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
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2Q4Q
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![BU of 2q4q by Molmil](/molmil-images/mine/2q4q) | Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.95870 | Descriptor: | UPF0366 protein C11orf67 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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1CGT
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![BU of 1cgt by Molmil](/molmil-images/mine/1cgt) | |
1NF9
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![BU of 1nf9 by Molmil](/molmil-images/mine/1nf9) | Crystal Structure of PhzD protein from Pseudomonas aeruginosa | Descriptor: | FORMIC ACID, octyl beta-D-glucopyranoside, phenazine biosynthesis protein phzD | Authors: | Parsons, F, Calabrese, K, Eisenstein, E, Ladner, J.E. | Deposit date: | 2002-12-13 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and mechanism of Pseudomonas aeruginosa PhzD, an isochorismatase from the phenazine biosynthetic pathway Biochemistry, 42, 2003
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1CH5
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![BU of 1ch5 by Molmil](/molmil-images/mine/1ch5) | RECOMBINANT SPERM WHALE MYOGLOBIN H97V MUTANT (MET) | Descriptor: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Liong, E.C, Phillips Jr, G.N. | Deposit date: | 1999-03-31 | Release date: | 1999-04-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Waterproofing the heme pocket. Role of proximal amino acid side chains in preventing hemin loss from myoglobin. J.Biol.Chem., 276, 2001
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1UXR
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![BU of 1uxr by Molmil](/molmil-images/mine/1uxr) | Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lorentzen, E, Hensel, R, Pohl, E. | Deposit date: | 2004-03-01 | Release date: | 2004-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
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1D45
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![BU of 1d45 by Molmil](/molmil-images/mine/1d45) | DNA DODECAMER C-G-C-G-A-A-T-T-C-G-C-G/HOECHST 33258 COMPLEX:-25 DEGREES C, PIPERAZINE DOWN | Descriptor: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | Authors: | Quintana, J.R, Lipanov, A.A, Dickerson, R.E. | Deposit date: | 1991-06-04 | Release date: | 1992-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Low-temperature crystallographic analyses of the binding of Hoechst 33258 to the double-helical DNA dodecamer C-G-C-G-A-A-T-T-C-G-C-G. Biochemistry, 30, 1991
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2GU2
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![BU of 2gu2 by Molmil](/molmil-images/mine/2gu2) | Crystal Structure of an Aspartoacylase from Rattus norvegicus | Descriptor: | Aspa protein, SULFATE ION, ZINC ION | Authors: | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-04-28 | Release date: | 2006-06-20 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | Structure of aspartoacylase, the brain enzyme impaired in Canavan disease. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1CSE
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![BU of 1cse by Molmil](/molmil-images/mine/1cse) | |
2PR3
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![BU of 2pr3 by Molmil](/molmil-images/mine/2pr3) | Factor XA inhibitor | Descriptor: | (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X, ... | Authors: | Zhang, E, Kohrt, J.T, Bigge, C.F, Finzel, B.C. | Deposit date: | 2007-05-03 | Release date: | 2007-08-14 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors Chem.Biol.Drug Des., 69, 2007
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4NB5
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![BU of 4nb5 by Molmil](/molmil-images/mine/4nb5) | |
4BCQ
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![BU of 4bcq by Molmil](/molmil-images/mine/4bcq) | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor | Descriptor: | 4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile, CYCLIN-A2, CYCLIN-DEPENDENT KINASE 2 | Authors: | Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M. | Deposit date: | 2012-10-02 | Release date: | 2013-01-09 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity. J.Med.Chem., 56, 2013
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1NF8
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![BU of 1nf8 by Molmil](/molmil-images/mine/1nf8) | Crystal structure of PhzD protein active site mutant with substrate | Descriptor: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, octyl beta-D-glucopyranoside, phenazine biosynthesis protein phzD | Authors: | Parsons, F, Calabrese, K, Eisenstein, E, Ladner, J.E. | Deposit date: | 2002-12-13 | Release date: | 2003-06-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and mechanism of Pseudomonas aeruginosa PhzD, an isochorismatase from the phenazine biosynthetic pathway Biochemistry, 42, 2003
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3GAN
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![BU of 3gan by Molmil](/molmil-images/mine/3gan) | Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CHLORIDE ION, Uncharacterized protein At3g22680 | Authors: | Burgie, E.S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2009-02-17 | Release date: | 2009-03-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin To be Published
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1CH9
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![BU of 1ch9 by Molmil](/molmil-images/mine/1ch9) | RECOMBINANT SPERM WHALE MYOGLOBIN H97Q MUTANT (MET) | Descriptor: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Liong, E.C, Phillips Jr, G.N. | Deposit date: | 1999-03-31 | Release date: | 1999-04-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Waterproofing the heme pocket. Role of proximal amino acid side chains in preventing hemin loss from myoglobin. J.Biol.Chem., 276, 2001
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2Q4N
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![BU of 2q4n by Molmil](/molmil-images/mine/2q4n) | Ensemble refinement of the crystal structure of protein from Arabidopsis thaliana At1g79260 | Descriptor: | Uncharacterized protein At1g79260 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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3C84
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![BU of 3c84 by Molmil](/molmil-images/mine/3c84) | Crystal structure of a complex of AChBP from aplysia californica and the neonicotinoid thiacloprid | Descriptor: | ISOPROPYL ALCOHOL, MAGNESIUM ION, Soluble acetylcholine receptor, ... | Authors: | Talley, T.T, Harel, M, Hibbs, R.E, Tomizawa, M, Casida, J.E, Taylor, P.W. | Deposit date: | 2008-02-08 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1CO8
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![BU of 1co8 by Molmil](/molmil-images/mine/1co8) | RECOMBINANT SPERM WHALE MYOGLOBIN L104A MUTANT (MET) | Descriptor: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Liong, E.C, Phillips Jr, G.N. | Deposit date: | 1999-06-07 | Release date: | 1999-06-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Waterproofing the heme pocket. Role of proximal amino acid side chains in preventing hemin loss from myoglobin. J.Biol.Chem., 276, 2001
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3C0S
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![BU of 3c0s by Molmil](/molmil-images/mine/3c0s) | UVDE 3 metals | Descriptor: | MANGANESE (II) ION, SODIUM ION, UV endonuclease | Authors: | Meulenbroek, E.M, Paspaleva, K, Thomassen, E.A.J, Abrahams, J.P, Goosen, N, Pannu, N.S. | Deposit date: | 2008-01-21 | Release date: | 2008-12-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Involvement of a carboxylated lysine in UV damage endonuclease Protein Sci., 18, 2009
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1T9M
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![BU of 1t9m by Molmil](/molmil-images/mine/1t9m) | X-ray crystal structure of phzG from pseudomonas aeruginosa | Descriptor: | ACETIC ACID, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | Authors: | Parsons, J.F, Eisenstein, E, Ladner, J.E. | Deposit date: | 2004-05-18 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the phenazine biosynthesis enzyme PhzG. Acta Crystallogr.,Sect.D, 60, 2004
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4B7T
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![BU of 4b7t by Molmil](/molmil-images/mine/4b7t) | Glycogen Synthase Kinase 3 Beta complexed with Axin Peptide and Leucettine L4 | Descriptor: | (5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-methyl-2-(propan-2-ylamino)imidazol-4-one, AXIN-1, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Oberholzer, A.E, Pearl, L.H. | Deposit date: | 2012-08-22 | Release date: | 2013-01-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.772 Å) | Cite: | Selectivity, Cocrystal Structures, and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B. J.Med.Chem., 55, 2012
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2GVI
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![BU of 2gvi by Molmil](/molmil-images/mine/2gvi) | |
4B7M
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![BU of 4b7m by Molmil](/molmil-images/mine/4b7m) | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | van der Vries, E, Vachieri, S.G, Xiong, X, Liu, J, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | Deposit date: | 2012-08-21 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
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2F6Z
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![BU of 2f6z by Molmil](/molmil-images/mine/2f6z) | Protein tyrosine phosphatase 1B with sulfamic acid inhibitors | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein phosphatase, ... | Authors: | Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R. | Deposit date: | 2005-11-29 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors Bioorg.Med.Chem.Lett., 16, 2006
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