PDB: 222624 resultsInfo pagesStatus searchChemie searchBIRD

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1M5K	Crystal structure of a hairpin ribozyme in the catalytically-active conformation Descriptor: CALCIUM ION, CHLORIDE ION, PROTEIN (U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A), ... Authors: Rupert, P.B, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-08-02 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
4NLD	Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with BMS-791325 also known as (1aR,12bS)-8-cyclohexyl-n-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide and 2-(4-fluorophenyl)-n-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide Descriptor: (1aR,12bS)-8-cyclohexyl-N-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide, 2-(4-fluorophenyl)-N-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide, RNA-directed RNA polymerase, ... Authors: Sheriff, S. Deposit date: 2013-11-14 Release date: 2014-03-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Discovery and Preclinical Characterization of the Cyclopropylindolobenzazepine BMS-791325, A Potent Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase. J.Med.Chem., 57, 2014
4EU6	Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA, acetate, and covalent acetylglutamyl anhydride and glutamyl-CoA thioester adducts Descriptor: ACETATE ION, CHLORIDE ION, COENZYME A, ... Authors: Mullins, E.A, Kappock, T.J. Deposit date: 2012-04-25 Release date: 2012-10-10 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.988 Å) Cite: Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases. Biochemistry, 51, 2012
1M5V	Transition State Stabilization by a Catalytic RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ... Authors: Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
1ZZN	Crystal structure of a group I intron/two exon complex that includes all catalytic metal ion ligands. Descriptor: 197-MER, 5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*GP*AP*CP*GP*GP*CP*C)-3', 5'-R(*CP*AP*(5MU))-3', ... Authors: Stahley, M.R, Strobel, S.A. Deposit date: 2005-06-14 Release date: 2005-08-30 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.37 Å) Cite: Structural evidence for a two-metal-ion mechanism of group I intron splicing. Science, 309, 2005
4G22	Structure of a Lys-HCT mutant from Coffea canephora (Crystal form 1) Descriptor: CHLORIDE ION, GLYCEROL, Hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyltransferase Authors: McCarthy, A.A, Lallemand, L.A, McCarthy, J.G. Deposit date: 2012-07-11 Release date: 2012-08-01 Last modified: 2012-11-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A structural basis for the biosynthesis of the major chlorogenic acids found in coffee. Plant Physiol., 160, 2012
1M5O	Transition State Stabilization by a Catalytic RNA Descriptor: CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ... Authors: Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
1SCS	HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS Descriptor: CALCIUM ION, COBALT (II) ION, CONCANAVALIN A Authors: Emmerich, C, Helliwell, J.R, Redshaw, M, Naismith, J.H, Harrop, S.J, Raftery, J, Kalb, A.J, Yariv, J, Dauter, Z, Wilson, K.S. Deposit date: 1993-12-06 Release date: 1994-05-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.6 Å) Cite: High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A. Acta Crystallogr.,Sect.D, 50, 1994
4KY9	Structural and Functional Analysis of a Putative Substrate Access Tunnel in the Cytosolic Domain of Human Anion Exchanger 1 Descriptor: Band 3 anion transport protein Authors: Shnitsar, V, Calmettes, C, Reithmeier, R.A.F, Moraes, T.F. Deposit date: 2013-05-28 Release date: 2013-10-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.23 Å) Cite: A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters. J.Biol.Chem., 288, 2013
4PUZ	Crystal structure of spleen tyrosine kinase (Syk) in complex with GS-9973 Descriptor: 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine, Tyrosine-protein kinase SYK Authors: Lansdon, E.B, Mitchell, S.A. Deposit date: 2014-03-14 Release date: 2014-04-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.085 Å) Cite: Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase. J.Med.Chem., 57, 2014
2AXT	Crystal Structure of Photosystem II from Thermosynechococcus elongatus Descriptor: (1S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-1-[(TRIDECANOYLOXY)METHYL]ETHYL PALMITATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... Authors: Loll, B, Kern, J, Saenger, W, Zouni, A, Biesiadka, J. Deposit date: 2005-09-06 Release date: 2005-12-27 Last modified: 2017-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Towards complete cofactor arrangement in the 3.0 A resolution structure of photosystem II NATURE, 438, 2005
1M5P	Transition State Stabilization by a Catalytic RNA Descriptor: CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ... Authors: Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
1VS2	Interactions of quinoxaline antibiotic and DNA: the molecular structure of a TRIOSTIN A-D(GCGTACGC) complex Descriptor: 2-CARBOXYQUINOXALINE, 5'-D(*GP*CP*GP*TP*AP*CP*GP*C)-3', TRIOSTIN A Authors: Wang, A.H.-J, Ughetto, G, Quigley, G.J, Rich, A. Deposit date: 1986-10-21 Release date: 2006-06-27 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Interactions of Quinoxaline Antibiotic and DNA: The Molecular Structure of a Triostin A-D(Gcgtacgc) Complex. J.Biomol.Struct.Dyn., 4, 1986
1VTE	MOLECULAR STRUCTURE OF NICKED DNA. MODEL A4 Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*T)-3'), DNA (5'-D(*TP*TP*CP*GP*CP*G)-3') Authors: Aymani, J, Coll, M, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. Deposit date: 1990-05-21 Release date: 2011-07-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Molecular structure of nicked DNA: a substrate for DNA repair enzymes. Proc. Natl. Acad. Sci. U.S.A., 87, 1990
1MAG	GRAMICIDIN A IN HYDRATED DMPC BILAYERS, SOLID STATE NMR Descriptor: GRAMICIDIN A Authors: Ketchem, R.R, Roux, B, Cross, T.A. Deposit date: 1996-06-06 Release date: 1997-01-11 Last modified: 2023-11-15 Method: SOLID-STATE NMR Cite: Macromolecular Structural Elucidation with Solid-State NMR-Derived Orientational Constraints. J.Biomol.NMR, 8, 1996
1MIC	GRAMICIDIN A: LEFT-HANDED PARALLEL DOUBLE HELICAL FORM IN METHANOL IN THE PRESENCE OF CACL2, NMR, 20 STRUCTURES Descriptor: GRAMICIDIN A Authors: Chen, Y, Tucker, A, Wallace, B.A. Deposit date: 1996-05-22 Release date: 1997-02-12 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Solution Structure of a Parallel Left-Handed Double-Helical Gramicidin-A Determined by 2D 1H NMR. J.Mol.Biol., 264, 1996
1VTG	THE MOLECULAR STRUCTURE OF A DNA-TRIOSTIN A COMPLEX Descriptor: 2-CARBOXYQUINOXALINE, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), triostin A Authors: Wang, A.H.-J, Ughetto, G, Quigley, G.J, Hakoshima, T, Van Der Marel, G.A, Van Boom, J.H, Rich, A. Deposit date: 1988-08-18 Release date: 2011-07-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.67 Å) Cite: The molecular structure of a DNA-triostin A complex. Science, 225, 1984
4LXV	Crystal Structure of the Hemagglutinin from a H1N1pdm A/WASHINGTON/5/2011 virus Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Yang, H, Chang, J.C, Guo, Z, Carney, P.J, Shore, D.A, Donis, R.O, Cox, N.J, Villanueva, J.M, Klimov, A.I, Stevens, J. Deposit date: 2013-07-30 Release date: 2014-02-26 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins. J.Virol., 88, 2014
3QIX	Crystal Structure of BoNT/A LC with Zinc bound Descriptor: 1,2-ETHANEDIOL, Botulinum neurotoxin type A, ZINC ION Authors: Thompson, A.A, Han, G.W, Stevens, R.C. Deposit date: 2011-01-28 Release date: 2011-04-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.413 Å) Cite: Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility. Biochemistry, 50, 2011
5OUZ	Metal free structure of Y40F SynFtn Descriptor: Ferritin Authors: Hemmings, A.M, Bradley, J.M. Deposit date: 2017-08-25 Release date: 2019-01-23 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.081 Å) Cite: Reaction of O2with a diiron protein generates a mixed-valent Fe2+/Fe3+center and peroxide. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4HLZ	Crystal Structure of Fab C179 in Complex with a H2N2 influenza virus hemagglutinin Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dreyfus, C, Wilson, I.A. Deposit date: 2012-10-17 Release date: 2013-04-17 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of a classical broadly neutralizing stem antibody in complex with a pandemic h2 influenza virus hemagglutinin. J.Virol., 87, 2013
4E80	Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase Descriptor: Poly(A) RNA polymerase protein cid1, URIDINE 5'-TRIPHOSPHATE Authors: Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. Deposit date: 2012-03-19 Release date: 2012-07-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.02 Å) Cite: Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
1BGA	BETA-GLUCOSIDASE A FROM BACILLUS POLYMYXA Descriptor: BETA-GLUCOSIDASE A Authors: Sanz-Aparicio, J, Hermoso, J.A, Martinez-Ripoll, M, Polaina, J. Deposit date: 1997-04-04 Release date: 1998-04-15 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of beta-glucosidase A from Bacillus polymyxa: insights into the catalytic activity in family 1 glycosyl hydrolases. J.Mol.Biol., 275, 1998
1X39	Crystal structure of barley beta-D-glucan glucohydrolase isoenzyme exo1 in complex with gluco-phenylimidazole Descriptor: (5R,6R,7S,8S)-3-(ANILINOMETHYL)-5,6,7,8-TETRAHYDRO-5-(HYDROXYMETHYL)-IMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-xylopyranose-(1-2)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: Hrmova, M, Streltsov, V.A, Smith, B.J, Vasella, A, Varghese, J.N, Fincher, G.B. Deposit date: 2005-05-02 Release date: 2005-12-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural rationale for low-nanomolar binding of transition state mimics to a family GH3 beta-D-glucan glucohydrolase from barley. Biochemistry, 44, 2005
1X38	crystal structure of barley beta-D-glucan glucohydrolase isoenzyme exo1 in complex with gluco-phenylimidazole Descriptor: (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-PHENYL-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-xylopyranose-(1-2)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: Hrmova, M, Streltsov, V.A, Smith, B.J, Vasella, A, Varghese, J.N, Fincher, G.B. Deposit date: 2005-05-02 Release date: 2005-12-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Structural rationale for low-nanomolar binding of transition state mimics to a family GH3 beta-D-glucan glucohydrolase from barley. Biochemistry, 44, 2005

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