PDB: 224004 resultsInfo pagesStatus searchChemie searchBIRD

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7NLA	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-119 Descriptor: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-22 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
4U9G	Crystal structure of an H-NOX protein from S. oneidensis in the Fe(II)CO ligation state, Q154A/Q155A/K156A mutant Descriptor: CARBON MONOXIDE, NO-binding heme-dependent sensor protein, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. Deposit date: 2014-08-06 Release date: 2014-10-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
7NLE	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-118 Descriptor: 14-3-3 protein sigma, 4-(4-methylpiperazin-1-yl)sulfonylbenzaldehyde, CHLORIDE ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-22 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7MYS	Crystal structure of a tRNA (guanine-N1)-methyltransferase from Acinetobacter baumannii AB5075-UW bound to S-adenosyl homocysteine Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-05-21 Release date: 2021-06-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of a tRNA (guanine-N1)-methyltransferase from Acinetobacter baumannii AB5075-UW bound to S-adenosyl homocysteine To Be Published
7P5O	Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate Descriptor: 1,6-di-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase Authors: Raimi, O.G, Yan, K, van Aalten, D.M.F. Deposit date: 2021-07-14 Release date: 2022-07-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus To Be Published
7NJ9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-133 Descriptor: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinolin-1-ylsulfonyl)benzaldehyde, DI(HYDROXYETHYL)ETHER, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-16 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NM9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-110 Descriptor: 14-3-3 protein sigma, 6-(2-bromanylimidazol-1-yl)pyridine-3-carbaldehyde, DI(HYDROXYETHYL)ETHER, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-23 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-132 Descriptor: 14-3-3 protein sigma, 4-piperidin-1-ylsulfonylbenzaldehyde, CHLORIDE ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-16 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
4TUV	X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-chlorophenyl)imidazole Descriptor: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 119, PROTOPORPHYRIN IX CONTAINING FE Authors: Madrona, Y. Deposit date: 2014-06-24 Release date: 2015-02-18 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.501 Å) Cite: NMR and X-ray Analysis of CYP119 Ligand Dependent Conformational Changes. To Be Published
7NK3	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-128 Descriptor: 14-3-3 protein sigma, 2-(4-methylphenyl)sulfonyl-3,4-dihydro-1~{H}-isoquinoline, CALCIUM ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-17 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NIF	14-3-3 sigma with Pin1 binding site pS72 and covalently bound TCF521-011 Descriptor: 1-(4-methylphenyl)imidazole, 14-3-3 protein sigma, CALCIUM ION, ... Authors: Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. Deposit date: 2021-02-12 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TZB	Structure of NDM-Metallo-beta-lactamase Descriptor: CADMIUM ION, COBALT (II) ION, Metallo-beta-lactamase, ... Authors: Ferguson, J.A, Makena, A, Brem, J, McDonough, M.A, Schofield, C.J. Deposit date: 2014-07-09 Release date: 2015-07-22 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.029 Å) Cite: Structure of Metallo-beta-lactamase To Be Published
7NJ8	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1007 Descriptor: 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ... Authors: Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. Deposit date: 2021-02-16 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TVO	Structure of Malate Dehydrogenase from Mycobacterium tuberculosis Descriptor: Malate dehydrogenase, SODIUM ION, SULFATE ION Authors: Ferraris, D.M, Rizzi, M. Deposit date: 2014-06-27 Release date: 2015-01-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis. Proteins, 83, 2015
7SBU	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a highly potent antibody J08 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, J08 Fab heavy chain, ... Authors: Liu, H, Wilson, I.A. Deposit date: 2021-09-25 Release date: 2022-05-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
7NJ6	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1005 Descriptor: 14-3-3 protein sigma, 4-[4-(trifluoromethyl)imidazol-1-yl]benzaldehyde, CALCIUM ION, ... Authors: Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. Deposit date: 2021-02-16 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TZ7	Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha Authors: Hu, J, Qin, Y, Wang, J, Li, L, Wu, D, Ha, Y. Deposit date: 2014-07-09 Release date: 2015-09-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled. Nat Commun, 6, 2015
7NIX	14-3-3 sigma with AS160 binding site pT642 Descriptor: 14-3-3 protein sigma, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MAGNESIUM ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-02-14 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TZJ	Structure of C. elegans HIM-3 bound to HTP-3 closure motif-4 Descriptor: C. elegans HIM-3 and HTP-3 Authors: Rosenberg, S.C, Corbett, K.D. Deposit date: 2014-07-10 Release date: 2014-11-19 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.851 Å) Cite: The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins. Dev.Cell, 31, 2014
7N63	X-ray structure of HCAN_0200, an aminotransferase from Helicobacter canadensis in complex with its external aldimine Descriptor: (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Griffiths, W.A, Heisdorf, C.J, Thoden, J.B, Holden, H.M. Deposit date: 2021-06-07 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
7NIG	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1008 Descriptor: 14-3-3 protein sigma, 2-bromanyl-4-imidazol-1-yl-benzaldehyde, CALCIUM ION, ... Authors: Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. Deposit date: 2021-02-12 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4U18	Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase (ISO-ECI2) Descriptor: CHLORIDE ION, Enoyl-CoA delta isomerase 2, mitochondrial, ... Authors: Onwukwe, G.U, Koski, M.K, Wierenga, R.K. Deposit date: 2014-07-15 Release date: 2014-12-24 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. Febs J., 282, 2015
7N7B	crystal structure of the N-formyltrasferase HCAN_0200 from Helicobacter canadensis on complex with folinic acid and dTDP-3-aminofucose Descriptor: (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... Authors: Heisdorf, C.J, Thoden, J.B, Holden, H.M. Deposit date: 2021-06-10 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
4U1C	Crystal structure of the eIF3a/eIF3c PCI-domain heterodimer Descriptor: Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C Authors: Erzberger, J.P, Schaefer, T, Ban, N. Deposit date: 2014-07-15 Release date: 2014-09-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex. Cell, 158, 2014
7NJA	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1006 Descriptor: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... Authors: Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. Deposit date: 2021-02-16 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021

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