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8A3W	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE Descriptor: 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, 40S ribosomal protein S2, ... Authors: Rajan, K.S, Yonath, A, Bashan, A. Deposit date: 2022-06-09 Release date: 2023-12-20 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE To Be Published
5GJP	Crystal structure of SrLDC in complex with PLP and Cadaverine Descriptor: GLYCEROL, Lysine/ornithine decarboxylase, MAGNESIUM ION, ... Authors: Sagong, H.-Y, Kim, K.-J. Deposit date: 2016-07-01 Release date: 2016-11-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure and Pyridoxal 5-Phosphate Binding Property of Lysine Decarboxylase from Selenomonas ruminantium PLoS ONE, 11, 2016
5FGF	Yeast 20S proteasome beta5-H(-2)A-T1A-K81R triple mutant in complex with Carfilzomib Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... Authors: Huber, E.M, Groll, M. Deposit date: 2015-12-20 Release date: 2016-03-23 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome. Nat Commun, 7, 2016
5CGF	Yeast 20S proteasome beta5-G48C mutant Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... Authors: Dubiella, C, Groll, M. Deposit date: 2015-07-09 Release date: 2015-11-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine. Angew.Chem.Int.Ed.Engl., 54, 2015
5BZ2	CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION Descriptor: Na(+)/H(+) antiporter Authors: Coincon, M, Uzdavinys, P, Cameron, A, Drew, D. Deposit date: 2015-06-11 Release date: 2016-01-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters. Nat.Struct.Mol.Biol., 23, 2016
4QNK	The structure of wt A. thaliana IGPD2 in complex with Mn2+ and phosphate Descriptor: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, ... Authors: Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W. Deposit date: 2014-06-18 Release date: 2015-06-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
5DGF	Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-27 Release date: 2016-12-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
5G3Z	Crystal structure of adenylate kinase ancestor 3 with Zn, Mg and Ap5A bound Descriptor: ADENYLATE KINSE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... Authors: Nguyen, V, Kutter, S, English, J, Kern, D. Deposit date: 2016-05-03 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Evolutionary drivers of thermoadaptation in enzyme catalysis. Science, 355, 2017
5DGE	Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-27 Release date: 2017-01-25 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
4U50	Crystal structure of Verrucarin bound to the yeast 80S ribosome Descriptor: (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
5CEH	Structure of histone lysine demethylase KDM5A in complex with selective inhibitor Descriptor: 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, NICKEL (II) ION, ... Authors: Kiefer, J.R, Vinogradova, M. Deposit date: 2015-07-06 Release date: 2016-05-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.14 Å) Cite: An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat.Chem.Biol., 12, 2016
4TZA	TGP, an extremely thermostable green fluorescent protein created by structure-guided surface engineering Descriptor: Fluorescent Protein Authors: Close, D.W, Bradbury, A.R.M. Deposit date: 2014-07-09 Release date: 2014-10-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structure-guided surface engineering. Proteins, 83, 2015
4U4Y	Crystal structure of Pactamycin bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U56	Crystal structure of Blasticidin S bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4TZG	Crystal structure of eCGP123, an extremely thermostable green fluorescent protein Descriptor: Fluorescent Protein Authors: Close, D.W, Don Paul, C, Traore, D.A.K, Wilce, M.C.J, Prescott, M, Bradbury, A.R.M. Deposit date: 2014-07-10 Release date: 2014-10-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structure-guided surface engineering. Proteins, 83, 2015
4U51	Crystal structure of Narciclasine bound to the yeast 80S ribosome Descriptor: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 18S ribosomal RNA, 25S ribosomal RNA, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4O	Crystal structure of Geneticin bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U53	Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome Descriptor: (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, 18S ribosomal RNA, 25S ribosomal RNA, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
1ZIP	BACILLUS STEAROTHERMOPHILUS ADENYLATE KINASE Descriptor: ADENYLATE KINASE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MANGANESE (II) ION, ... Authors: Berry, M.B, Phillips Jr, G.N. Deposit date: 1997-05-07 Release date: 1997-08-20 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+. Proteins, 32, 1998
5DAT	Complex of yeast 80S ribosome with hypusine-containing eIF5A Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-20 Release date: 2016-08-31 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
4U4R	Crystal structure of Lactimidomycin bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.801 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4N	Crystal structure of Edeine bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4TYQ	Crystal structure of an adenylate kinase mutant--AKm2 Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CALCIUM ION, ... Authors: Moon, S, Bae, E. Deposit date: 2014-07-09 Release date: 2014-11-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures of thermally stable adenylate kinase mutants designed by local structural entropy optimization and structure-guided mutagenesis J KOREAN SOC APPL BIOL CHEM, 57, 2014
5DGV	Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog Descriptor: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-28 Release date: 2016-12-14 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
2AK3	THE THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN MITOCHONDRIAL MATRIX ADENYLATE KINASE AND ITS SUBSTRATE AMP AT 1.85 ANGSTROMS RESOLUTION Descriptor: ADENOSINE MONOPHOSPHATE, ADENYLATE KINASE ISOENZYME-3, SULFATE ION Authors: Diederichs, K, Schulz, G.E. Deposit date: 1995-03-07 Release date: 1995-05-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The refined structure of the complex between adenylate kinase from beef heart mitochondrial matrix and its substrate AMP at 1.85 A resolution. J.Mol.Biol., 217, 1991

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