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4J2W
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BU of 4j2w by Molmil
Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4J36
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BU of 4j36 by Molmil
Cocrystal Structure of kynurenine 3-monooxygenase in complex with UPF 648 inhibitor(KMO-394UPF)
Descriptor: (1S,2S)-2-(3,4-dichlorobenzoyl)cyclopropanecarboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4J34
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BU of 4j34 by Molmil
Crystal Structure of kynurenine 3-monooxygenase - truncated at position 394 plus HIS tag cleaved.
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4JY3
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BU of 4jy3 by Molmil
Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-pyridoxic acid bound form
Descriptor: 1,2-ETHANEDIOL, 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxy-4-(hydroxymethyl)-6-methylpyridine-3-carboxylic acid, ...
Authors:Kobayashi, J, Yoshida, H, Kamitori, S, Hayashi, H, Mizutani, K, Takahashi, N, Mikami, B, Yagi, T.
Deposit date:2013-03-29
Release date:2014-04-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
4K22
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BU of 4k22 by Molmil
Structure of the C-terminal truncated form of E.Coli C5-hydroxylase UBII involved in ubiquinone (Q8) biosynthesis
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Pecqueur, L, Lombard, M, Golinelli-pimpaneau, B, Fontecave, M.
Deposit date:2013-04-07
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:ubiI, a New Gene in Escherichia coli Coenzyme Q Biosynthesis, Is Involved in Aerobic C5-hydroxylation.
J.Biol.Chem., 288, 2013
4JY2
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BU of 4jy2 by Molmil
Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, native and unliganded form
Descriptor: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Kobayashi, J, Yoshida, H, Kamitori, S, Hayashi, H, Mizutani, K, Takahashi, N, Mikami, B, Yagi, T.
Deposit date:2013-03-28
Release date:2014-04-02
Method:X-RAY DIFFRACTION (1.935 Å)
Cite:Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
4J33
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BU of 4j33 by Molmil
Crystal Structure of kynurenine 3-monooxygenase (KMO-394)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
6C7S
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BU of 6c7s by Molmil
Structure of Rifampicin Monooxygenase with Product Bound
Descriptor: (1E,3S,4R,5S,6R,7R,8R,9S,10S,11E,13E)-15-amino-1-{[(2S)-5,7-dihydroxy-2,4-dimethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,6,9-trioxo-1,2,6,9-tetrahydronaphtho[2,1-b]furan-2-yl]oxy}-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxopentadeca-1,11,13-trien-5-yl acetate, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Liu, L.-K, Tanner, J.J.
Deposit date:2018-01-23
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Evidence for Rifampicin Monooxygenase Inactivating Rifampicin by Cleaving Its Ansa-Bridge.
Biochemistry, 57, 2018
4X4J
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BU of 4x4j by Molmil
Structural and Functional Studies of BexE: Insights into Oxidation During BE-7585A Biosynthesis
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative oxygenase, SULFATE ION
Authors:Tsai, S.-C, Jackson, D.R, Patel, A, Barajas, J.F, Rohr, J, Yu, X, Liu, H.-W, Sasaki, E, Calveras, J, Metsa-Ketela, M.
Deposit date:2014-12-02
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and Functional Studies of BexE: Insights into Oxidation During BE-7585A Biosynthesis
To Be Published
2DKH
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BU of 2dkh by Molmil
Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni, in complex with the substrate
Descriptor: 3-HYDROXYBENZOIC ACID, 3-hydroxybenzoate hydroxylase, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Hiromoto, T, Fujiwara, S, Hosokawa, K, Yamaguchi, H.
Deposit date:2006-04-11
Release date:2006-10-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site
J.Mol.Biol., 364, 2006
2DKI
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BU of 2dki by Molmil
Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni, under pressure of xenon gas (12 atm)
Descriptor: 3-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Hiromoto, T, Fujiwara, S, Hosokawa, K, Yamaguchi, H.
Deposit date:2006-04-11
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site
J.Mol.Biol., 364, 2006
5KOW
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BU of 5kow by Molmil
Structure of rifampicin monooxygenase
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase
Authors:Tanner, J.J, Liu, L.-K.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
5KOX
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BU of 5kox by Molmil
Structure of rifampicin monooxygenase complexed with rifampicin
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase, RIFAMPICIN
Authors:Tanner, J.J, Liu, L.-K.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
6U0S
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BU of 6u0s by Molmil
Crystal structure of the flavin-dependent monooxygenase PieE in complex with FAD and substrate
Descriptor: 2,4-dichlorophenol 6-monooxygenase, 2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-6-methoxy-3-methylpyridin-4-ol, CHLORIDE ION, ...
Authors:Shi, R, Manenda, M.
Deposit date:2019-08-14
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations.
J.Biol.Chem., 295, 2020
6U0P
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BU of 6u0p by Molmil
Crystal structure of PieE, the flavin-dependent monooxygenase involved in the biosynthesis of piericidin A1
Descriptor: 2,4-dichlorophenol 6-monooxygenase, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Shi, R, Manenda, M, Picard, M.-E.
Deposit date:2019-08-14
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations.
J.Biol.Chem., 295, 2020
6UI5
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BU of 6ui5 by Molmil
Tmn9 in complex with cofactor FAD
Descriptor: 2-polyprenyl-6-methoxyphenol hydroxylase-like FAD-dependent oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Paiva, F.C.R, Little, R, Leadlay, P, Dias, M.V.B.
Deposit date:2019-09-30
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tmn9 in complex with cofactor FAD
To Be Published
7OUJ
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BU of 7ouj by Molmil
Crystal structure of the flavoprotein monooxygenase RubL from rubromycin biosynthesis
Descriptor: (2S)-hexane-1,2,6-triol, 4-HYDROXYPROLINE, CHLORIDE ION, ...
Authors:Saleem-Batcha, R, Toplak, M, Teufel, R.
Deposit date:2021-06-11
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7OUC
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BU of 7ouc by Molmil
Crystal structure of the flavoprotein monooxygenase GrhO5 from griseorhodin A biosynthesis
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent monooxygenase GrhO5
Authors:Saleem-Batcha, R, Toplak, M, Teufel, R.
Deposit date:2021-06-11
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7OUD
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BU of 7oud by Molmil
Crystal structure of a ternary complex of the flavoprotein monooxygenase GrhO5 with FAD and collinone
Descriptor: Collinone, FAD-dependent monooxygenase GrhO5, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R, Toplak, M, Teufel, R.
Deposit date:2021-06-11
Release date:2021-11-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7VWP
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BU of 7vwp by Molmil
Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FlsO1, PHOSPHATE ION, ...
Authors:Zhang, Y, Yang, C, Zhang, L, Zhang, C.
Deposit date:2021-11-11
Release date:2022-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation
Nat Commun, 13, 2022
6EM0
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BU of 6em0 by Molmil
Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase M321A from Pseudomonas azelaica
Descriptor: 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Deri, B, Bregman-Cohen, A, Pazy Benhar, Y, Fishman, A.
Deposit date:2017-10-01
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Altering 2-Hydroxybiphenyl 3-Monooxygenase Regioselectivity by Protein Engineering for the Production of a New Antioxidant.
Chembiochem, 19, 2018
6J0Z
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BU of 6j0z by Molmil
Crystal structure of AlpK
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative angucycline-like polyketide oxygenase
Authors:Wang, W, Liu, Y, Liang, H.
Deposit date:2018-12-27
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.889 Å)
Cite:Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019
3EPT
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BU of 3ept by Molmil
Structure of the rebeccamycin biosynthetic enzyme RebC with reduced flavin
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, RebC, SODIUM ION
Authors:Ryan, K.S, Drennan, C.L.
Deposit date:2008-09-30
Release date:2008-12-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:The FAD cofactor of RebC shifts to an IN conformation upon flavin reduction
Biochemistry, 47, 2008
4Z2U
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BU of 4z2u by Molmil
Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase R242Q from Pseudomonas azelaica
Descriptor: 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kanteev, M, Bregman-Cohen, A, Fishman, A.
Deposit date:2015-03-30
Release date:2015-08-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism.
Biochim.Biophys.Acta, 1854, 2015
4Z2T
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BU of 4z2t by Molmil
Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase W225Y from Pseudomonas azelaica
Descriptor: 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kanteev, M, Bregman-Cohen, A, Fishman, A.
Deposit date:2015-03-30
Release date:2015-08-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism.
Biochim.Biophys.Acta, 1854, 2015

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数据于2024-06-26公开中

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