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1BNJ
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BU of 1bnj by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 9.0
Descriptor: BARNASE
Authors:Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BNR
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BU of 1bnr by Molmil
BARNASE
Descriptor: BARNASE (G SPECIFIC ENDONUCLEASE)
Authors:Bycroft, M.
Deposit date:1995-03-31
Release date:1995-07-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy.
Biochemistry, 30, 1991
1BRK
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BU of 1brk by Molmil
BARNASE MUTANT WITH ILE 96 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BNE
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BU of 1bne by Molmil
BARNASE A43C/S80C DISULFIDE MUTANT
Descriptor: BARNASE
Authors:Clarke, J, Henrick, K, Fersht, A.R.
Deposit date:1995-03-31
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography.
J.Mol.Biol., 253, 1995
1BSA
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BU of 1bsa by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1B20
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BU of 1b20 by Molmil
DELETION OF A BURIED SALT-BRIDGE IN BARNASE
Descriptor: PROTEIN (BARNASE), ZINC ION
Authors:Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R.
Deposit date:1998-12-03
Release date:1998-12-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1CH0
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BU of 1ch0 by Molmil
RNASE T1 VARIANT WITH ALTERED GUANINE BINDING SEGMENT
Descriptor: CALCIUM ION, CHLORIDE ION, GUANOSINE-2'-MONOPHOSPHATE, ...
Authors:Hoeschler, K, Hoier, H, Orth, P, Hubner, B, Saenger, W, Hahn, U.
Deposit date:1999-03-30
Release date:1999-12-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of an RNase T1 variant with an altered guanine binding segment.
J.Mol.Biol., 294, 1999
1DE3
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BU of 1de3 by Molmil
SOLUTION STRUCTURE OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN
Descriptor: RIBONUCLEASE ALPHA-SARCIN
Authors:Perez-Canadillas, J.M, Campos-Olivas, R, Santoro, J, Lacadena, J, Martinez del Pozo, A, Gavilanes, J.G, Rico, M, Bruix, M.
Deposit date:1999-11-12
Release date:2000-06-21
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The highly refined solution structure of the cytotoxic ribonuclease alpha-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity.
J.Mol.Biol., 299, 2000
1B21
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BU of 1b21 by Molmil
DELETION OF A BURIED SALT BRIDGE IN BARNASE
Descriptor: PROTEIN (BARNASE), ZINC ION
Authors:Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R.
Deposit date:1998-12-03
Release date:1998-12-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1B2M
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BU of 1b2m by Molmil
THREE-DIMENSIONAL STRUCTURE OF RIBONULCEASE T1 COMPLEXED WITH AN ISOSTERIC PHOSPHONATE ANALOGUE OF GPU: ALTERNATE SUBSTRATE BINDING MODES AND CATALYSIS.
Descriptor: 5'-R(*GP*(U34))-3', RIBONUCLEASE T1
Authors:Arni, R.K, Watanabe, L, Ward, R.J, Kreitman, R.J, Kumar, K, Walz Jr, F.G.
Deposit date:1998-11-27
Release date:1999-03-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
Biochemistry, 38, 1999
1BAN
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BU of 1ban by Molmil
THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS
Descriptor: BARNASE
Authors:Chen, Y.W, Fersht, A.R, Henrick, K.
Deposit date:1993-05-19
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants.
J.Mol.Biol., 234, 1993
1BRN
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BU of 1brn by Molmil
SUBSITE BINDING IN AN RNASE: STRUCTURE OF A BARNASE-TETRANUCLEOTIDE COMPLEX AT 1.76 ANGSTROMS RESOLUTION
Descriptor: DNA (5'-D(*CP*GP*AP*C)-3'), PROTEIN (BARNASE (E.C.3.1.27.-))
Authors:Buckle, A.M, Fersht, A.R.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-A resolution.
Biochemistry, 33, 1994
1BSC
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BU of 1bsc by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BVI
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BU of 1bvi by Molmil
RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
Authors:Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J.
Deposit date:1998-09-15
Release date:1998-09-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
1BOX
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BU of 1box by Molmil
N39S MUTANT OF RNASE SA FROM STREPTOMYCES AUREOFACIENS
Descriptor: GUANYL-SPECIFIC RIBONUCLEASE SA
Authors:Hebert, E.J, Giletto, A, Sevcik, J, Urbanikova, L, Wilson, K.S, Dauter, Z, Pace, C.N.
Deposit date:1998-08-07
Release date:1999-12-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Contribution of a conserved asparagine to the conformational stability of ribonucleases Sa, Ba, and T1.
Biochemistry, 37, 1998
1BNI
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BU of 1bni by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 6.0
Descriptor: BARNASE
Authors:Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BRJ
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BU of 1brj by Molmil
BARNASE MUTANT WITH ILE 88 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRH
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BU of 1brh by Molmil
BARNASE MUTANT WITH LEU 14 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1B2X
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BU of 1b2x by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 7.5 FROM A CRYO_COOLED CRYSTAL AT 100K
Descriptor: PROTEIN (BARNASE), ZINC ION
Authors:Harrison, P, Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-12-03
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1DET
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BU of 1det by Molmil
RIBONUCLEASE T1 CARBOXYMETHYLATED AT GLU 58 IN COMPLEX WITH 2'GMP
Descriptor: GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1, SODIUM ION
Authors:Ishikawa, K, Suzuki, E, Tanokura, M, Takahashi, K.
Deposit date:1996-02-20
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of ribonuclease T1 carboxymethylated at Glu58 in complex with 2'-GMP.
Biochemistry, 35, 1996
7MRX
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BU of 7mrx by Molmil
Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/C82A
Descriptor: Barstar, Ribonuclease
Authors:Caro, J.A, Smith, J, Wand, A.J.
Deposit date:2021-05-10
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Conformational entropy and protein affinity
To Be Published
6PQK
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BU of 6pqk by Molmil
Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/S59C/A67C/C82A
Descriptor: 1,2-ETHANEDIOL, Barstar, PHOSPHATE ION, ...
Authors:Caro, J.A, Djanto, V, Wand, A.J.
Deposit date:2019-07-09
Release date:2020-07-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Targeting conformational entropy to modulate binding affinity
To Be Published
3DA7
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BU of 3da7 by Molmil
A conformationally strained, circular permutant of barnase
Descriptor: Barnase circular permutant, Barstar
Authors:Mitrousis, G, Butler, J, Loh, S.N, Cingolani, G.
Deposit date:2008-05-28
Release date:2009-04-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and thermodynamic analysis of a conformationally strained circular permutant of barnase.
Biochemistry, 48, 2009
1X1Y
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BU of 1x1y by Molmil
Water-mediate interaction at aprotein-protein interface
Descriptor: Barstar, Ribonuclease
Authors:Ikura, T, Urakubo, Y, Ito, N.
Deposit date:2005-04-15
Release date:2005-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Water-mediated interaction at a protein-protein interface
Chem.Phys., 307, 2004
1X1U
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BU of 1x1u by Molmil
Water-mediate interaction at aprotein-protein interface
Descriptor: Barstar, Ribonuclease
Authors:Ikura, T, Urakubo, Y, Ito, N.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Water-mediated interaction at a protein-protein interface
Chem.Phys., 307, 2004

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数据于2024-08-14公开中

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