9CQT
 
 | | Human OxyHb (C2 symmetry) obtained using the SPT Labtech chameleon In the presence of 5 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.37 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQP
 | | Human metHb (C2 symmetry) obtained using the SPT Labtech chameleon | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQO
 | | Human metHb (C1 symmetry) obtained using the SPT Labtech chameleon | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQW
 | | Human DeoxyHb (C2 symmetry) obtained using the SPT Labtech chameleon In the presence of 60 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQS
 | | Human OxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 5 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQQ
 | | Human metHb (C1 symmetry) obtained using the SPT Labtech chameleon under Al's Oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQM
 | | Human OxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 25 uM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQU
 | | Human OxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 20 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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6VDS
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Iron(III) Deuteroporphyrin IX and Substrate 4-bromo-ortho-cresol | | Descriptor: | 1,2-ETHANEDIOL, 4-bromo-2-methylphenol, Dehaloperoxidase B, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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6VDT
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Iron(III) Deuteroporphyrin IX and Substrate 4-nitrophenol | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dehaloperoxidase B, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.978 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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6VD4
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6VD3
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6VDW
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Manganese(III) Porphyrin and Substrate 4-nitrophenol | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dehaloperoxidase B, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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6VDU
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Iron(III) Deuteroporphyrin IX and Substrate Trichlorophenol | | Descriptor: | 1,2-ETHANEDIOL, 2,4,6-trichlorophenol, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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6VDV
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Manganese(III)- Porphyrin and Substrate 4-bromophenol | | Descriptor: | 1,2-ETHANEDIOL, 4-BROMOPHENOL, Dehaloperoxidase B, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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6VDY
 | | Crystal Structure of Dehaloperoxidase B wild type in Complex with Substrate Trichlorophenol | | Descriptor: | 1,2-ETHANEDIOL, 2,4,6-trichlorophenol, Dehaloperoxidase B, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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9BCJ
 | | Crystal structure of human hemoglobin in complex with the HbpA receptor from Corynebacterium diphtheriae | | Descriptor: | GLYCEROL, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Mahoney, B.J, Cascio, D, Clubb, R.T. | | Deposit date: | 2024-04-09 | | Release date: | 2025-01-08 | | Method: | X-RAY DIFFRACTION (1.691 Å) | | Cite: | Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6VDX
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Manganese(III)- Porphyrin and Substrate Trichlorophenol | | Descriptor: | 1,2-ETHANEDIOL, 2,4,6-trichlorophenol, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. | | Deposit date: | 2019-12-27 | | Release date: | 2020-12-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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6VD6
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6VD5
 | | Crystal Structure of Dehaloperoxidase B in Complex with cofactor Iron(III) Mesoporphyrin IX and Substrate Trichlorophenol | | Descriptor: | 1,2-ETHANEDIOL, 2,4,6-trichlorophenol, Dehaloperoxidase B, ... | | Authors: | Ghiladi, R.A, de Serrano, V.S, Malewschik, T. | | Deposit date: | 2019-12-23 | | Release date: | 2020-12-23 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme
To Be Published
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8WIZ
 | | cryo-EM structure of alligator haemoglobin in deoxy form | | Descriptor: | BICARBONATE ION, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-08-14 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM.
Nat Commun, 15, 2024
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8WIY
 | | cryo-EM structure of alligator haemoglobin in oxy form | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-08-14 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (2.31 Å) | | Cite: | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM.
Nat Commun, 15, 2024
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8WJ0
 | | cryo-EM structure of human haemoglobin in carbonmonoxy form | | Descriptor: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-08-14 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (2.24 Å) | | Cite: | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM.
Nat Commun, 15, 2024
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8WJ1
 | | cryo-EM structure of human haemoglobin in oxy form | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-08-14 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (2.27 Å) | | Cite: | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM.
Nat Commun, 15, 2024
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8WIX
 | | cryo-EM structure of alligator haemoglobin in carbonmonoxy form | | Descriptor: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Takahashi, K, Lee, Y, Fago, A, Bautista, N.M, Kawamoto, A, Kurisu, G, Storz, J, Nishizawa, T, Tame, J.R.H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-08-14 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM.
Nat Commun, 15, 2024
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