5WG6
 
 | | Human Polycomb Repressive Complex 2 in complex with GSK126 inhibitor | | Descriptor: | 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine N-methyltransferase EZH2,Polycomb protein SUZ12 (E.C.2.1.1.43) chimera, Polycomb protein EED, ... | | Authors: | Bratkowski, M.A, Liu, X. | | Deposit date: | 2017-07-13 | | Release date: | 2018-06-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.901 Å) | | Cite: | An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors.
Sci Rep, 8, 2018
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5XTZ
 | | Crystal structure of GAS41 YEATS bound to H3K27ac peptide | | Descriptor: | ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4 | | Authors: | Li, H.T, Zhao, D. | | Deposit date: | 2017-06-21 | | Release date: | 2018-06-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.105 Å) | | Cite: | Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
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5YUG
 | | AtVAL1 PHD-Like domain in the P31 space group | | Descriptor: | B3 domain-containing transcription repressor VAL1, GLYCEROL, ZINC ION | | Authors: | Zhang, M.M, Wu, B.X. | | Deposit date: | 2017-11-22 | | Release date: | 2018-05-02 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | AtVAL1 PHD-Like domain in the P31 space group
To Be Published
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6A58
 | | Structure of histone demethylase REF6 | | Descriptor: | Lysine-specific demethylase REF6, ZINC ION | | Authors: | Tian, Z, Chen, Z. | | Deposit date: | 2018-06-22 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms.
Cell Discov, 6, 2020
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6A57
 | | Structure of histone demethylase REF6 complexed with DNA | | Descriptor: | DNA (5'-D(*CP*TP*TP*TP*CP*TP*CP*TP*GP*TP*TP*TP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*AP*AP*A)-3'), GLYCEROL, ... | | Authors: | Tian, Z, Chen, Z. | | Deposit date: | 2018-06-22 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms.
Cell Discov, 6, 2020
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