8V5P
 
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8V5Q
 | | Varicella Zoster Virus (VZV) glycoprotein E (gE) gI binding domain in complex with human Fab 1E3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Envelope glycoprotein E, Fab 1E3 Heavy Chain, ... | | Authors: | Holzapfel, G, Seraj, N, Harshbarger, W. | | Deposit date: | 2023-11-30 | | Release date: | 2024-12-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of the Varicella Zoster Virus Glycoprotein E and Epitope Mapping of Vaccine-Elicited Antibodies.
Vaccines (Basel), 12, 2024
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8VFM
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5W3Q
 | | L28F E.coli DHFR in complex with NADPH | | Descriptor: | CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Oyen, D, Wright, P.E, Wilson, I.A. | | Deposit date: | 2017-06-08 | | Release date: | 2017-08-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J. Am. Chem. Soc., 139, 2017
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8ELM
 | | Apo human biliverdin reductase beta (293K) | | Descriptor: | Flavin reductase (NADPH), SODIUM ION | | Authors: | McLeod, M.J, Eisenmesser, E.Z, Lee, E, Thorne, R.E. | | Deposit date: | 2022-09-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle.
Front Mol Biosci, 10, 2023
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8ELL
 | | Apo human biliverdin reductase beta (cryogenic) | | Descriptor: | Flavin reductase (NADPH), SODIUM ION | | Authors: | McLeod, M.J, Eisenmesser, E.Z, Lee, E, Thorne, R.E. | | Deposit date: | 2022-09-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle.
Front Mol Biosci, 10, 2023
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6OH1
 | | IgA1 Protease G5 domain structure | | Descriptor: | Immunoglobulin A1 protease | | Authors: | Eisenmesser, E.Z, Chi, Y.C, Paukovich, N, Redzic, J.S, Rahkola, J.T, Janoff, E.N. | | Deposit date: | 2019-04-04 | | Release date: | 2020-02-26 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Streptococcus pneumoniae G5 domains bind different ligands.
Protein Sci., 28, 2019
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2XSC
 | | Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli | | Descriptor: | SHIGA-LIKE TOXIN 1 SUBUNIT B, ZINC ION | | Authors: | Stein, P.E, Boodhoo, A, Tyrrell, G.J, Brunton, J.L, Oeffner, R.D, Bunkoczi, G, Read, R.J. | | Deposit date: | 2010-09-27 | | Release date: | 2010-10-13 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.052 Å) | | Cite: | Crystal Structure of the Cell-Binding B Oligomer of Verotoxin-1 from E. Coli.
Nature, 355, 1992
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6FJM
 | | tubulin-Disorazole Z complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Disorazole Z, ... | | Authors: | Menchon, G, Prota, A.E, Lucena Agell, D, Bucher, P, Jansen, R, Irschik, H, Mueller, R, Paterson, I, Diaz, J.F, Altmann, K.-H, Steinmetz, M.O. | | Deposit date: | 2018-01-22 | | Release date: | 2018-05-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.
Nat Commun, 9, 2018
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4ZT1
 | | Crystal structure of human E-Cadherin (residues 3-213) in x-dimer conformation | | Descriptor: | CALCIUM ION, Cadherin-1 | | Authors: | Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E. | | Deposit date: | 2015-05-14 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction.
J.Med.Chem., 59, 2016
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8UIZ
 | | In situ human P-E state 80S ribosome | | Descriptor: | 18S rRNA [Homo sapiens], 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Wei, Z, Yong, X. | | Deposit date: | 2023-10-10 | | Release date: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | In situ human P-E state 80S ribosome
To Be Published
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4ZTE
 | | Crystal structure of human E-Cadherin (residues 3-213) in complex with a peptidomimetic inhibitor | | Descriptor: | CALCIUM ION, Cadherin-1, N-{[(2S,5S)-1-benzyl-5-(2-{[(2S,3S)-1-(tert-butylamino)-3-methyl-1-oxopentan-2-yl]amino}-2-oxoethyl)-3,6-dioxopiperazin-2-yl]methyl}-L-alpha-asparagine | | Authors: | Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E. | | Deposit date: | 2015-05-14 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction.
J.Med.Chem., 59, 2016
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6OFE
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8R7Z
 | | transcription factor BARHL2 homodimer with spacing four bp | | Descriptor: | BarH-like 2 homeobox protein, DNA (5'-D(P*AP*CP*CP*GP*TP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*AP*CP*GP*GP*T)-3'), ... | | Authors: | Morgunova, E, Popov, A, Yin, Y, Taipale, J. | | Deposit date: | 2023-11-27 | | Release date: | 2024-12-04 | | Last modified: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (3.26 Å) | | Cite: | DNA-guided transcription factor interactions extend human gene regulatory code.
Nature, 641, 2025
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1K3F
 | | Uridine Phosphorylase from E. coli, Refined in the Monoclinic Crystal Lattice | | Descriptor: | uridine phosphorylase | | Authors: | Morgunova, E.Yu, Mikhailov, A.M, Popov, A.N, Blagova, E.V, Smirnova, E.A, Vainshtein, B.K, Mao, C, Armstrong, S.R, Ealick, S.E, Komissarov, A.A, Linkova, E.V, Burlakova, A.A, Mironov, A.S, Debabov, V.G. | | Deposit date: | 2001-10-02 | | Release date: | 2001-10-10 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Atomic structure at 2.5 A resolution of uridine phosphorylase from E. coli as refined in the monoclinic crystal lattice.
FEBS Lett., 367, 1995
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5U7F
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5U7H
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8JJ6
 | | Structure of the NELF-BCE complex | | Descriptor: | NELF-E, Negative elongation factor B, Negative elongation factor complex member C/D | | Authors: | Wang, Z, Cao, Y, Qin, Y. | | Deposit date: | 2023-05-29 | | Release date: | 2023-08-30 | | Last modified: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Structural basis of the human negative elongation factor NELF-B/C/E ternary complex.
Biochem.Biophys.Res.Commun., 677, 2023
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8R7F
 | | Transcription factor BARHL2 homodimer with spacing two bp | | Descriptor: | BarH-like 2 homeobox protein, DNA (5'-D(*CP*TP*AP*AP*AP*CP*GP*GP*GP*CP*AP*AP*TP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*AP*TP*TP*GP*CP*CP*CP*GP*TP*TP*TP*AP*G)-3') | | Authors: | Morgunova, E, Popov, A, Yin, Y, Taipale, J. | | Deposit date: | 2023-11-24 | | Release date: | 2024-12-04 | | Last modified: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | DNA-guided transcription factor interactions extend human gene regulatory code.
Nature, 641, 2025
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1ED3
 | | CRYSTAL STRUCTURE OF RAT MINOR HISTOCOMPATIBILITY ANTIGEN COMPLEX RT1-AA/MTF-E. | | Descriptor: | BETA-2-MICROGLOBULIN, CLASS I MAJOR HISTOCOMPATIBILITY ANTIGEN RT1-AA, PEPTIDE MTF-E (13N3E) | | Authors: | Speir, J.A, Stevens, J, Joly, E, Butcher, G.W, Wilson, I.A. | | Deposit date: | 2000-01-26 | | Release date: | 2001-02-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.
Immunity, 14, 2001
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3TTO
 | | Crystal structure of Leuconostoc mesenteroides NRRL B-1299 N-terminally truncated dextransucrase DSR-E in triclinic form | | Descriptor: | CALCIUM ION, Dextransucrase, GLYCEROL | | Authors: | Brison, Y, Pijning, T, Fabre, E, Mourey, L, Morel, S, Potocki-Veronese, G, Monsan, P, Tranier, S, Remaud-Simeon, M, Dijkstra, B.W. | | Deposit date: | 2011-09-15 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Functional and structural characterization of alpha-(1-2) branching sucrase derived from DSR-E glucansucrase
J.Biol.Chem., 287, 2012
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6OPL
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1SE7
 | | Solution structure of the E. coli bacteriophage P1 encoded HOT protein: a homologue of the theta subunit of E. coli DNA polymerase III | | Descriptor: | HOMOLOGUE OF THE THETA SUBUNIT OF DNA POLYMERASE III | | Authors: | DeRose, E.F, Kirby, T.W, Mueller, G.A, Chikova, A.K, Schaaper, R.M, London, R.E. | | Deposit date: | 2004-02-16 | | Release date: | 2004-12-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Phage Like It HOT: Solution Structure of the Bacteriophage P1-Encoded HOT Protein, a Homolog of the theta Subunit of E. coli DNA Polymerase III
Structure, 12, 2004
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6NCU
 | | Interleukin-37 residues 53-206- dimer | | Descriptor: | Interleukin-37 | | Authors: | Eisenmesser, E.Z. | | Deposit date: | 2018-12-12 | | Release date: | 2019-03-13 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Interleukin-37 monomer is the active form for reducing innate immunity.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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4CSY
 | | E-selectin lectin, EGF-like and two SCR domains complexed with Sialyl Lewis X | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, E-SELECTIN, ... | | Authors: | Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T. | | Deposit date: | 2014-03-11 | | Release date: | 2014-09-24 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
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