PDB: 367 resultsInfo pagesStatus searchChemie searchBIRD

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5ILG	Crystal structure of photoreceptor dehydrogenase from Drosophila melanogaster Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Hofmann, L, Tsybovsky, Y, Banerjee, S. Deposit date: 2016-03-04 Release date: 2016-11-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family. Biochemistry, 55, 2016
4K6F	X-ray crystal structure of a putative Acetoacetyl-CoA reductase from Burkholderia cenocepacia bound to the co-factor NADP Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative Acetoacetyl-CoA reductase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-04-15 Release date: 2013-05-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: X-ray crystal structure of a putative Acetoacetyl-CoA reductase from Burkholderia cenocepacia bound to the co-factor NADP TO BE PUBLISHED
4J7X	Crystal structure of human sepiapterin reductase in complex with sulfasalazine Descriptor: 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Groenlund Pedersen, M, Pojer, F, Johnsson, K. Deposit date: 2013-02-14 Release date: 2014-02-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of human sepiapterin reductase in complex with sulfasalazine To be Published
5IF3	Crystal structure of a Short-chain dehydrogenase/reductase SDR from Burkholderia vietnamiensis Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-25 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of a Short-chain dehydrogenase/reductase SDR from Burkholderia vietnamiensis to be published
5IDW	Crystal structure of an oxidoreductase from Burkholderia vietnamiensis in complex with NADP Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-24 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of an oxidoreductase from Burkholderia vietnamiensis in complex with NADP to be published
5IG2	Crystal structure of a short chain dehydrogenase/reductase SDR from Burkholderia phymatum in complex with NAD Descriptor: ACETATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Short-chain dehydrogenase/reductase SDR Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-26 Release date: 2016-06-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a short chain dehydrogenase/reductase SDR from Burkholderia phymatum in complex with NAD to be published
7BTM	SDR protein/resistance protein NapW Descriptor: Short chain dehydrogenase Authors: Wen, W.H, Tang, G.L. Deposit date: 2020-04-02 Release date: 2021-10-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.08311653 Å) Cite: Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12, 2021
7BSX	SDR protein NapW-NADP Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase Authors: Wen, W.H, Tang, G.L. Deposit date: 2020-03-31 Release date: 2021-10-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12, 2021
5IDQ	Crystal structure of a Short-chain dehydrogenase/reductase (SDR)from Burkholderia vietnamiensis at 1.55 A resolution Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-24 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of a Short-chain dehydrogenase/reductase (SDR)from Burkholderia vietnamiensis at 1.55 A resolution to be published
4KZP	Crystal Structure of a Putative Short Chain Dehydrogenase from Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Oxidoreductase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-05-30 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Crystal Structure of a Putative Short Chain Dehydrogenase from Mycobacterium smegmatis To be Published
7ENY	Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli Descriptor: 7alpha-hydroxysteroid dehydrogenase Authors: Kim, K.-H, Lee, C.W, Pardhe, D.P, Hwang, J, Do, H, Lee, Y.M, Lee, J.H, Oh, T.-J. Deposit date: 2021-04-21 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.703 Å) Cite: Crystal structure of an apo 7 alpha-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding. J.Steroid Biochem.Mol.Biol., 212, 2021
4IS3	Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution Descriptor: ACETATE ION, Bile acid 3-alpha hydroxysteroid dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2013-01-16 Release date: 2013-04-24 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution To be published
2YUT	Crystal Structure of Putative Short-Chain Oxidoreductase TTHB094 from Thermus thermophilus HB8 Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative short-chain oxidoreductase Authors: Agari, Y, Shinkai, A, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-04-06 Release date: 2007-10-09 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of Putative Short-Chain Oxidoreductase TTHB094 from Thermus thermophilus HB8 To be Published
2YZ7	X-ray analyses of 3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis Descriptor: CALCIUM ION, CHLORIDE ION, D-3-hydroxybutyrate dehydrogenase Authors: Hoque, M.M, Juan, E.C.M, Shimizu, S, Hossain, M.T, Takenaka, A. Deposit date: 2007-05-04 Release date: 2008-04-22 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.19 Å) Cite: The structures of Alcaligenes faecalisD-3-hydroxybutyrate dehydrogenase before and after NAD(+) and acetate binding suggest a dynamical reaction mechanism as a member of the SDR family. Acta Crystallogr.,Sect.D, 64, 2008
8FD8	human 15-PGDH with NADH bound Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Authors: Huang, W, Taylor, D. Deposit date: 2022-12-02 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
8JAT	Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans Descriptor: 3-ketodihydrosphingosine reductase TSC10, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Zhao, P, Kuang, Z. Deposit date: 2023-05-07 Release date: 2023-06-21 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans. Biochem.Biophys.Res.Commun., 670, 2023
8J29	Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus Descriptor: GLYCEROL, L(+)-TARTARIC ACID, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2B	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, in complex with NADP+ and malonate Descriptor: MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2D	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, mutant N940V/K1106W/S1114R in complex with NADP+ Descriptor: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2A	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, in complex with NADP+ Descriptor: GLYCEROL, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2C	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, mutant N940V/K1106W/S1114R Descriptor: GLYCEROL, L(+)-TARTARIC ACID, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2E	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, mutant N940V/K1106W/S1114R in complex with NADP+ and malonate Descriptor: MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
4HFR	Human 11beta-Hydroxysteroid Dehydrogenase Type 1 in complex with an orally bioavailable acidic inhibitor AZD4017. Descriptor: Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {(3S)-1-[5-(cyclohexylcarbamoyl)-6-(propylsulfanyl)pyridin-2-yl]piperidin-3-yl}acetic acid Authors: Ogg, D.J, Gerhardt, S, Hargreaves, D. Deposit date: 2012-10-05 Release date: 2012-10-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Discovery of a Potent, Selective, and Orally Bioavailable Acidic 11 -Hydroxysteroid Dehydrogenase Type 1 (11 -HSD1) Inhibitor: Discovery of 2-[(3S)-1-[5-(Cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic Acid (AZD4017) J.Med.Chem., 55, 2012
8G84	Crystal structures of HSD17B13 complexes Descriptor: Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Liu, S. Deposit date: 2023-02-17 Release date: 2023-08-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.467 Å) Cite: Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
8G9V	Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13 Descriptor: 17-beta-hydroxysteroid dehydrogenase 13, 4-{[2,5-dimethyl-3-(4-methylbenzene-1-sulfonyl)benzene-1-sulfonyl]amino}benzoic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Liu, S. Deposit date: 2023-02-22 Release date: 2023-08-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.645 Å) Cite: Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023

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